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Foxh1, a Smad DNA-binding partner, mediates TGFβ-dependent gene expression during early development. Few Foxh1 targets are known. Here, we describe a genome-wide approach that we developed that couples systematic mapping of a functional Smad/Foxh1 enhancer to Site Search, a program used to search annotated genomes for composite response elements. Ranking of SFEs that are positionally conserved across species yielded a set of genes enriched in Foxh1 targets.

在最新的研究中，加拿大多伦多大学和英国阿伯丁大学的研究人员开发出一种新的生物信息学的方法，把Smad/Foxh1功能性增强子系列制图与定点查找结合起来，进行全基因组范围的Foxh1靶蛋白搜索，并将搜索结果按照其在生物间的保守性打分分级。

Cara Dillon 《BONNY BONNY》 Bonny, bonny was my seat in the red rosy yard And bonny was my ship in the town of Ballynagard Shade and shelter was for me till I began to fail You all may guess now my distress lies near the Nightingale Grief and woe that I must go to fight for England's King I neither know his friend or foe, and war's a cruel thing The nightingale is near at hand, my time at home is brief And Carey's steams and mountain land I part with bitter grief No more I'll walk the golden hills with Nancy by my side Or dream along the sun bright rills, or view my land with pride We sail away at dawn of day, the sails are ready set When old Benmore I see no more, I'll sigh with deep regret Now all must change and I must range across the ocean wide Our ship she may in Biscay's Bay lie low beneath the tide If I should fall by cannon ball, or sink beneath the sea Good people all, a tear let fall and mourn for mine and me If God should spare me my greying hair and bring me back again I'd love far more my Antrim shore, its dark blue hills and rain Around the fires, my heart's desires, heaven grant till life shall fail And keep me far from the cruel war and from the Nightingale bonny, bonny

是我玫瑰园的长椅 bonny， bonny，是为我遮风挡雨的小舟一叶只到有一天，我慢慢的倒下夜莺初啼，你会知道我我的烦恼为了国王我将踏上征程，悲伤懊恼填满我心我不知道谁是朋友谁是敌人，我只知道战争多么残酷夜莺初啼，我知道在家时日无多作别家乡的山水和故土，我悲伤满怀再不能和心上人，去到那夕阳下的青山再不能在梦里的山梁上，遥望家乡的土地我们在黎明即将上路，远航的风帆已经拉满当家乡渐行渐远，唯有叹息遗恨交织我心面目全非的我，要穿越那遥远的海峡我们的战船会停靠在比斯开湾，落潮的地方如果我倒在炮火中，或是长眠于深海善良的人们啊，请流下你一滴眼泪，为我和我的一切过往如果上苍染黑我花白的发丝，让我回到家乡我会更加热爱那金色海滩，蓝色的山梁和黑色的雨滴炉火边，让我的愿望在天堂里实现，只到我倒下的那一刻让我远离那残酷的战火，远离那夜莺的啼哭

Germany is the art of its variety, this will fundamentally a low-long-chef for the survival of their gold content of the market, the deepest feelings of their own kitchen-or the situation, with the same technology market was the lack of comparison to other cuisine The harmonization of norms of the market dynamic, first paid no attention to "the world such as small cooked fresh," it simply the word, creating the revitalization of Brand-kitchen-come first-served awakening chef de cuisine, not only upgrade skills, and spiritual needs of kitchen Germany, it is imperative that with the market screening, to be based from the start with, this matter is as essential to their kitchen to kitchen to self-cultivation, and the real chef who not only language but also to be used carefully Their situation to complete any of the beautiful dishes described, in recent years, talking about the catering industry within and outside the culture more and more, has also set up a wide range of research will be like, as an academic study, this, I think that deep Wei, Yi Utah 30 years ago, I followed as the father of one party chefs, chef at the outskirts of Chengdu Huayang a farm, his father Chef when I start, as was the object of that time, his father often As Niuguisheshen to criticized and denounced, is one of incrimination has been a well-known Zou Zipai private kitchen, and criticized and denounced Renru to accept the end of hope can be better comment to the rebels to their cooking, At that time my father often Fuzhao head repeatedly told, will do what is the other line cooks dry, but each time his father Renru for rebels who cook up the dishes are all highlights, Silk Bugou This Daorang adult years I shall understand that this may be the chef de bar, it is Yidebaoyuan Then, I really want to shake off family skills, dry point level, but overall I also can not cook to Wang Qing, the more its people despise and Bufen, who cooks for the next Jiu Liu said the people they do not know, the next Jiuliu What is not in all cooks, and why the system's contribution to cuisine, but also the people can not afford to do SUI I have suffered, Huang deep sense of business after I had promised a wish, I should not only serve the kitchen line, but also for the kitchen to the development and feel proud and elated, such as cooking guide me on it and make contribution to the cause of their fathers Hard work, in addition to the cause of prosperity Yan Wei, also comfort for the kitchen to numerous grievances life predecessors, that engage in this kind of a warning to clear the kitchen to cook things are by no means purely Shaocai Cook, but the real sentiment of the blending of life Wuwei is required for each entry-chef of a scholarship.

其艺其德可谓五花八门了，这样也就从根本上隆低了川厨们赖以生存的市场含金量了，感受最深的还是川厨们自身的处境，与之相同场竟技的其它菜系比较缺少了统一规范的市场活力，先不讲&天下事如烹小鲜&，那只是纯粹的一句话，打造川厨品牌形象振兴厨艺先得觉醒厨德，既提升技艺，更需要修行厨德，这是当务之急，有了市场的筛选，更需从基础说起了，这就是做为事厨者们必不可少的厨行修行了，而真正的厨者不是只用语言而是更要用心用情去完成自己任何一次美丽的菜品描述的，近年来，行业内外谈论饮食文化的越来越多了，还成立了各式各样的研究会之类，当作一门学问研究了，对此，我深以为慰，犹忆三十年前，我尾随作为一方名厨的父亲，就厨於成都华阳郊外的一家农场工作，父亲主厨我当下手，作为被那个年代改造的对象，父亲经常被当作牛鬼蛇神来批斗，其罪之一就是曾为某知名走资派做过私人厨事，而批斗完了还要忍辱接受可以被改造希望较好的评论，去给造反派们做饭，那时父亲经常抚著我的头顶一再叮嘱，干什麼都行，就是别乾厨师这一行，然而，每次父亲忍辱为其造反派们烹调出来的菜肴却都是可圈可点，丝丝不苟，这倒让我成年后多年都不得明白，这或许就是厨德吧，是以德报怨吧？再后来，我也的确想摆脱家传技艺，干点别的，可是，我总也忘情不了厨行，更为其被人鄙视而不忿，那些称厨师为下九流的人他们其实并不知道，下九流中什麼都有就是没有厨师，而为什麼制出美食贡献的人，却总也被人睢不起呢？我有身受，深感惶感，从业后我曾许了个心愿，我不仅要服务於厨行，更要为厨行的发展而扬眉吐气，如引导我走上为之烹饪事业贡献力量的父辈们努力工作，除了为事业的兴旺发达欣尉之外，还要告慰无数为厨行委屈终生的前辈们，搞明白了这样的一个忠告，才能清楚厨行的事厨者决非只是单纯的烧菜煮饭，而是真正感悟人生五味的调合才是每个川厨入门必修的一门学问。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。