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The iliac bone defect moulds were prepared and the compound scaffolds were implanted. The compound scaffolds were taken out after four and eight weeks separately, bone healing status and appearance of scaffolds were observed by eyes, the osteoplast growth status in compound scaffolds were viewed by HE and chinalizarin dyeing separately, the degradation of the compound scaffolds in vivo were observed by SEM.
制作髂骨骨缺损模型,在骨缺损处植入骨支架复合体,植入后4周、8周取材大体观察材料与周围骨愈合情况,HE染色及茜素红染色观察支架复合体内成骨细胞生长及扫描电镜观察支架体内降解情况。
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Methods Seventy-five SD rats were randomized into five groups: normal, model, iodine glycerin (20 g/L), high-dose SP (200 g/L) and low-dose SP (100 g/L). The experimental periodontitis rat models were established by ligating molars with steel wire combined with intramuscularly injection of prednisolone (1.25mg, 8 times). Except that the model and normal groups were treated by applying saline, the other groups were treated by applying the corresponding drugs 0.5 mL to the peridentium, tid for 10 days. After treatment, debris index, probe depth and bleeding rate during probing were investigated and the pathological changes of periodontal tissues were also observed.
方法]SD大鼠随机分为正常组,模型组,碘甘油组(20g/L),舒口散高、低剂量组(200、100 g/L);采用钢丝结扎牙齿加肌注波尼松龙(l.25 mg/次,共8次)的方法复制大鼠实验性牙周炎模型;药物采用口腔局部涂搽,每次0.5mL,每日3次,10 d为1疗程,模型组与正常组给予等容积生理盐水;检测各组软垢指数、探诊深度、探诊出血阳性例数,并取牙周组织进行病理学检查。
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Methods: Eighty mice were randomly divided into high, middle, and low dosage groups which were orally given 1.5 g/kg, 0.75 g/kg, 0. 375 g/kg of ant powder respectively, twice a day for 10 days. A blank control group was set up which was given water instead. Body weight, thymus weight and spleen weight were measured. Thymus indexes and spleen index were calculated. Neutrophil phagocytose rate, Ea and Et rosette formation rate of T lymphocytes, and hemolysin titre were detected. QHS values were achieved with spleen cell mediated sheep red cell spectrophotometer quantitative assay.
根据黑蚂蚁的用药量将小鼠分成高、中、低剂量及空白对照组,黑蚂蚁粉给药量按小鼠体重1.5g/kg、0.75g/kg、0.375g/kg计算,连续10d灌胃给药后,测定各组小鼠的体重、胸腺和脾脏重量,计算胸脾指数;检测中性粒细胞的吞噬率、T淋巴细胞E花环形成率及小鼠的溶血素效价和脾细胞介导的羊红细胞分光光度计定量测定法。
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Results In 9 cases of endometrial biopsy of materials by uterine curettage, the cells of endometrial stromal sarcomas of 6 cases were well differentiated and like stromal cells of endometrial hyperplasia; the cells of endometrial stromal sarcomas of 3 cases were poor differentiated, the cells of 2 were like that of malignant lymphoma, and another like that of pleomorphous sarcoma. In 9 cases were found the distribution of vessels cluster like endometrial corkscrew small artery. The tumor cells were grew along lymphatic or protruded in lymphatic, and there were small islands or small pieces of tumor cells in the interspace of muscles in 2 cases. The contrastive observation of the specimens of resected uterines of 9 cases confirmed the valve of above features to the confessed diagnosis of endometrial stromal sarcomas in the materials of endometrial biopsy or uterine curettage.
有3例分化差者,其中2例酷似恶性淋巴瘤,1例酷似多形性肉瘤。9例均见簇状分布的子宫内膜螺旋小动脉样的小血管分布,2例见瘤组织沿淋巴管和突入淋巴管内生长及小片平滑肌组织的肌间隙内有小灶状或小片状瘤组织分布。9例子宫切除标本的对比观察,进一步证实了上述特征对宫内膜活检或刮出物确诊子宫内膜间质肉瘤的价值。
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Methods: Wistar rats were divided into normal group, model group, TCM group Ⅰ, TCM group Ⅱ and western medicine group. In addition to the normal group, the other four groups were reproduced animal model of pulmonic fibrosis. The model group were given normal saline gavage, The TCM group Ⅰ given Feifltkang Mistura (1g/ml) gavage, The TCM group Ⅱ were given Fe4fukang Mistura (0.5g/ml) gavage, WM group were given prednisone gavage. Half of each group were taken blood to test in 28th, 56th day.
选择Wistar大白鼠随机分为正常组、模型组、中药Ⅰ组、中药Ⅱ组、西药组,除正常组外,其余四组均复制肺纤维化动物模型;模型组用生理盐水灌胃,中药Ⅰ、Ⅱ组分别用高、低剂量肺复康合剂灌胃,西药组用强的松灌胃;各组分别检测血清相关指标。
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There were no statistically differences between the 8th~ 14thday, the 15th - 21th day post-BC and the control group. During the rt~24tkday post-BC , pycnosis degeneration or necrosis neurons of the locus cerebral cortex, dorsal hippocampus, dentate fornix were significantly increased, then decreased gradually, but recovered to normal by the 24thday after BC, and especially in parietal cortex and piriform cortex the necrosis neurons were significantly increased than temporal cortex , and there were no statistically difference berween the left and the right side. Pycnosis degeneration or necrosis neurons in the brainstem reticular formation were markedly increased in the 4thday after BC, and there were no statistically difference among the other groups and the control group.
与对照组相比,BC后在大脑皮质、背侧海马和齿状回部位,固缩变性和不完全坏死细胞数先显著增加(P<0.05),然后逐渐减少,至24d基本恢复正常;顶叶、梨状皮质比颞叶皮质变性坏死细胞多,差异有高度显著性(P<0.01);大脑左侧比右侧变性坏死细胞稍少但差异无显著性;在BC后4d,脑桥核、斜方体核平面的脑干网状结构中固缩变性和不完全坏死细胞数明显增多(P<0.05),其它组间无显著性差异。
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Secondly,UV spectrophotometry was adopted to research the combination action on SM_2 and SIZ with MAA and 4-Vp.The combination action of functional monomer with template molecules were produced in the results. Then,the prediction imprinting principle of SM_2 and SIZ were given. The diagrams of infrared spectrum were analysed in MAA and 4-Vp and IMPs of SM_2. It was discoved that the absorbability peak of C=C function group in the IMPs were turn to be very low ,but the function group of carboxylic acid and pyridyl in the IMPs were no evidence change, and the condition was created in the molecular recognition of MIPs. Thermal Analysis was adopted to research IMPs ,in which ,a better thermal stability and its decompose temperature were showed in the results.
其次,本文利用紫外分光光度法研究磺胺二甲嘧啶和磺胺异噁唑与甲基丙烯酸或4-乙烯基吡啶的结合作用,结果表明,溶液中的功能单体与模板分子之间产生了结合作用,并预测磺胺二甲嘧啶和磺胺异噁唑印迹机理;分别分析了功能单体甲基丙烯酸、4-乙烯基吡啶、磺胺二甲嘧啶和磺胺异噁唑分子印迹聚合物的红外谱图,经过对比发现制得的印迹聚合物中C=C双键峰很小,并且功能键羧酸键和吡啶氮没有明显变化,这为聚合物特异识别特性创造了条件;利用综合热分析仪,对分子印迹聚合物进行综合热分析,结果表明分子印迹聚合物具有较好的热稳定性,分解温度也较高。
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These 375 patients had a median age of 50.57±10.46(range,19-72) with 87.4%HBsAg positive and 4.3%anti-HCV antibody positive;The apparent peak incidence age was 40~60 years old,and the ratio of male to female was 10.7:1;The 3 and 5 year postoperational survival rate were 52%and 38%;The tumour numbers(p=0.000),tumor size(p=0.025),histological pattern (p=0.000),nuclear features(p=0.000),differentiation(p=0.001) and vascular invasion(p=0.000) were significantly correlated with prognosis.The postoperational survival time of thin trabeculae pattern,compact pattern and pseudoglandular pattern were significantly longer than that of thick trabeculae, scirrhous pattern,and solid patternp<0.009the postoperational survival time of 1 and 2 grade based on nuclear features were significantly longer than that of 3 and 4 grades(p=0.000The small cell variant,osteoclast-like giant cell variant, and spindle cell variant were mainly composed of thick trabeculae pattern and solid pattern,which were significantly different from that of clear cell variant.
结果1。本组资料显示肝细胞癌发病年龄19~72岁,平均50.57±10.46岁,发病高峰年龄40~60岁,男女比例为10.7:1;HBsAg87.4%,anti-HCV抗体4.3%;术后3年生存率为52%,5年生存率为38%;肿瘤数目(p=0.000)、肿瘤大小(p=0.025)、组织学结构类型(p=0.000)、核分级(p=0.000)、分化程度(p=0.001)及血管浸润均(p=0.000)与预后明显相关;其中组织学结构类型中细梁状型生存时间与致密梁状型和腺样型无明显区别(p>0.05)而明显高于粗梁状型、实性型和硬化型(p≤0.009),硬化型生存时间与实性型之间无明显区(p>0.05)而明显低于其余各型p≤0.006核分级1级与2级生存时间无明显区别(p>0.05,核分级3级与4级生存时间无明显区别(p>0.05),而核分级3级生存时间明显低于2p=0.000小细胞型、巨细胞型和梭形细胞型主要由实性型和粗梁状型组织学结构类型构成,明显不同于透明细胞型(主要由细梁状型和粗梁状型构成(p≤1.006)。2。
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The above facts indicated that silicon accumulation in the rice leaf sheath inside, the leaf surface and the sclerenchymatous cell, played the physical barrier role, delayed the hypha of sheath blight expansion.5、Analysing the physiological and biochemical mechanism of the resistance to rice sheath blight improved by silicon application in several respects.(1) After being inoculated with R.solani, O2 and POD activities disordered, CAT activities obviously declined. O2 producingvelocity in 91SP\'s leaves and leaf sheaths of Si+ rice plants were lower than those of Siriceplants, MDA content in leaves and leaf sheaths of Si+ rice plants were lower thanthose of Si- rice plants significantly in three days after inoculating, SOD、POD、CATactivities in leaf sheaths of Si+ rice plants were higher than those of Si- rice plantssignificantly in one day after inoculating, SOD、POD、CAT activities in leaves ofSi-treatment were higher than those of Si- rice plants significantly in three days afterinoculating. O2 producing velocity and MDA content in Lemont\'s leaves and leafsheaths of Si+ rice plants were lower than those of Si- rice plants significantly afterinoculating, and SOD、POD、CAT activities of Si+ rice plants were higher than those ofSi- rice plants significantly.
说明硅在水稻叶鞘内侧、叶表和厚壁细胞积累,起到了物理屏障的作用,延缓了纹枯病菌的扩展。5、阐明了施硅增强水稻抗纹枯病的生理生化机制(1)接种纹枯病菌后,两个水稻品种91SP和Lemont的叶鞘和叶片超氧阴离子自由基O2性紊乱,CAT活性明显下降;抗病品种91SP叶鞘和叶片施硅处理的O2产生速率小于缺硅处理,叶鞘和叶片MDA含量在接种第3 d后显著低于缺硅处理,叶鞘SOD、POD、CAT活性在接种1 d后一直显著高于缺硅处理,叶片SOD、POD、CAT活性在接种3 d后显著高于缺硅处理;感病品种Lemont叶鞘和叶片施硅处理的O2产生速率、MDA含量始终显著小于缺硅处理,SOD、POD、CAT活性始终显著大于缺硅处理。
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Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.
成果包括:(1)在生物组织弹性成像方面,研究了多种图像校正方法和应变估计方法,进行了弹性重构和仿体、离体及在体超声弹性成像实验研究;(2)在生物微系统和微血管血流灌注成像方面,制备了三种不同包膜超声造影微泡,研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制,并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究;(3)在阵列式高强聚焦超声治疗与监控成像技术方面,设计制作了新的HIFU换能器,解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题,并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展,具有重要应用前景;(4)在语音听觉系统特别是嗓音康复方面,研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理,建立基于神经、肌肉和空气动力系统的综合补偿调节模型,提出了相应的评价系统。
- 相关中文对照歌词
- Hela Världen För Mig
- Din Första Kyss
- Sov Gott
- Fernando
- En Livstid I Krig
- Poltava
- Gott Mit Uns
- Ett Slag Färgat Rött
- Karolinens Bön
- Baksmälla
- 推荐网络例句
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Objective To investigate the relationship between ovum fertilization rate and sperm morphology, acrosome reaction in IVF and to explore the influence of parameters of sperm on fertilization rate.
目的 研究体外受精(in vitro fertilization,IVF)中精子形态、顶体反应与卵子受精率之间的关系,分析精子各参数在IVF受精率方面的参考意义。
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A: I hear Mr. White wants to run for the Presidency!
我听说怀特先生要参加总统竞选!
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It was a blowy day soon after Hilda had gone, that Mrs Bolton said: 'Now why do not you go for a walk through the wood, and look at the daffs behind the keeper's cottage?
希尔达走了不久以后的一个刮风天,波太太对她说:你为什么不到树林里去散散步,到守猎人的村舍后边去看看野水仙?