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The elimination half-life t(subscript β1/2 was 161.10h, 333.21 h and 611.26h, respectively, and the total body clearance was 27.4mL/, 16.8g/ and 18.0g/, respectively. The metabolite ciprofloxacin concentration-time profiles of the plasma, muscle and liver presented similar trend. The multi- peak phenomenon were observed in the plasma, muscle and liver, but the first peak time was 24h, 24h and 12h, respectively. The peak residue of metabolite ciprofloxacin was in liver, muscle and plasma, ordinally. The eliminating rate of ciprofloxacin from muscle and liver was very low.

代谢物环丙沙星在鳗鲡血浆、肌肉和肝脏中药物水平的变化趋势与恩诺沙星基本相似，呈现出多峰现象，但3种组织中环丙沙星出现第一个药峰时间分别为给药后第24小时、24小时和12小时，3种组织中环丙沙星峰值水平肝脏中最高、肌肉中次之、血浆中最低，环丙沙星在肌肉和肝脏中的消除速率比较缓慢。

RESULTS:① The demonstrating rate of intrahepatic bile duct calculus was 87.5% and that of other parts was 100%.② The rate of orientative diagnosis of choledocholithiasis was 94.7%, that of intrahepatic bile buct calculus was 75.0％ and that of other parts was

结果：①定位诊断：对肝内胆管结石梗阻部位显示率为87.5%，对其他梗阻部位显示率为100%；②定性诊断：术前诊断胆总管结石正确率为94.7%，肝内胆管结石正确率为75.0%，其他胆道梗阻正确率为90.9%～100%。

While the molar ratio of WD-20 and tetraethyl orthosilicate was 0.2, the sol-fraction of the prepared nanocomposites was 6%,glass transition temperature was above 250 ℃ and the transmittance was more than 80% at the wavelength between 450 nm and 800 nm and the size of dispersed SiO2 phase was less than 100 nm.

当WD-20与四乙基原硅酸盐之比为0.2时，所制备的纳米复合材料的溶胶分数为6%、玻璃化转变温度为250 ℃以上、可见光透过率在80％以上、SiO2分散相尺寸小于100 nm。

MAIN OUTCOME MEASURES: The morphology of BMSCs was observed by the inverted phase contrast microscope. Expression of BMSC surface antigens was detected by flow cytometer. Osteogenous potential was assessed by alkaline phosphatase staining. Adipogenic potential was evaluated by Oil red O staining. Chondrogenic potential was assessed by toluidine blue staining.

主要观察指标：倒置相差显微镜下观察骨髓间充质干细胞的生长状态，流式细胞仪检测细胞表面标志物的表达，采用碱性磷酸酶染色鉴定成骨能力，以油红O染色鉴定成脂能力，以甲苯胺蓝染色鉴定成软骨能力。

Results indicate that the number of bacteria grown in media LB, CSEA and WSA was 14.84×10^7, 10.27×10^7 and 6.91×10^7 CFU per gram dry soil, respectively, after 192 h of incubation. The diversity index of soil bacteria was the highest in WSA, while the lowest in LB. Certain similarity was discovered in bacteria community between the three media, i. e. the Jaccard index was 57.69% between LB and CSEA, 53.13% between LB and WSA and 66.67% between CSEA and WSA. Phylogenetic analysis suggests that the dominant bacterial groups in the soil belong to β-Proteobacteria,γ-Proteobacteria and Actinobacteria. The sequence of 16S rDNA of some OTUs was found to have high homology with Burkholderiaceae bacterium, Rhodococcus and Mycobacterium, so it is presumed that the cells of these bacteria can secrete Resuscitation-Promoting Factors, which may effectively improve culturability of soil microorganisms.

结果表明，LB、CSEA、WSA培养基192h后每g干土获得的细菌数量分别为14.84×10^7、10.27×10^7和6.91×10^7CFU，但微生物多样性指数以WSA为最高，LB多样性指数最低；三种培养基培养的细菌菌群有一定的相似性，LB和CSEA培养基间的Jaccard指数为57.69%，LB和WSA培养基之间为53.13%，而CSEA和WSA培养基的相似性指数达66.67%；16SrDNA测序结果表明，所获得的土壤细菌优势种群在分类方面主要属于γ-和β-变形杆菌以及放线菌亚门，其中某些OTUs中的16SrDNA序列与Burkholderiaceae bacterium、Rhodococcus和Mycobacterium属具有较高的同源性，推测其细胞能够分泌复苏促进因子，有效地提高土壤细菌的可培养性。

Results showed that, pyrolin had obvious action on two species of fungi, and the antifungal effect was positively correlative with concentration. The EC50 was 0.4076 mg/mL and 0.4626 mg/mL respectively after cultured 3 days. The main antifungal period was the fast growth period of fungi, and lead to it lag behind. Observation under SEM revealed that pyrolin caused a series of marked morphological and structural alterations of hyphal. These changes included mutual adhesion of mycelium, the hyphal was irregular in diameter, local denting, some of mycelium was broken, disruption of cell wall, outbreaking of inner cytoplast, and the empty cavity appeared. As a result, pyrolin restrained the growth of these fungi.

结果表明，鹿蹄草素对上述两种真菌均具有明显的抑制作用，抑菌效果与浓度呈正相关，培养3d时的EC50分别为0.4076、0.4626 mg/mL；抑菌时期主要是在真菌的快速生长期，使其快速生长期滞后；扫描电镜显示，鹿蹄草素作用下菌体形态发生异常变化，表现为菌丝体之间相互粘连，菌丝粗细不均匀，细胞壁破裂，局部凹陷，部分菌丝断裂，大量内容物外溢，出现空腔等现象，从而发挥其抑菌作用。

Methods Rhizoma Gastrodiae, Pellis Ovis, and Calculus Bovis Sativus in Tianhuang Houzao powder were identified by TLC. The content of Gastrodin in the powder was determined by HPLC. The HPLC condition was as follows: column was Phenomenex C18 (4.60 mm×250 mm, 4 m), the mobile phase consisted of methanol-0.05% phosphoric acid (3:97), the UV detection wavelength was at 220 nm, the flow rate was 1.0 ml/min with column temperature at 25℃.

用薄层色语法鉴别天黄猴枣散中天麻、猴枣、体外培育牛黄；用高效液相色谱法对制剂中天麻素进行定量分析，Phenomenex C18 (4.60 mm×250 mm， 4 m)色谱柱，流动相为甲醇－0.05%磷酸溶液(3：97)；检测波长220 nm，流速1.0 ml/min，柱温25 ℃。

Results:There were no abdominal pain and fever,jaundice faded away gradually postoperation.Biliary drainage was 300ml-1000ml/d more or less.Colour of bile changed into normal by degrees.Intra peritoneal drainage was open and the colour was light bloody.Amount of drainage dropped off day after day.Whole blood cell test, serum glutamic pyruvic transaminase,serum glutamic oxalacetic transarninase,total serum protein,serum albumin and serum globulin returned to normal in first week postoperation.Serum bilirubin,serum glutamyltranspetidase and serum alkaline phosphatase declined gradually in first week postoperation.T-tube was clipped at twelfth day postoperation.T-tube Cholangiography was clear at 24~ day postoperation.

结果：术后无上腹部绞痛、高热，黄疸逐渐减退，每日引流胆汁300ml-1000ml不等，由淡黄色混浊、内有胆泥过渡到金黄色清亮的正常胆汁，腹腔引流通畅，引流液为淡红色，量从最初的200ml迅速过渡到10ml，血常规、血清谷丙转氨酶、谷草转氨酶、总蛋白、白蛋白、球蛋白等1周内均恢复正常，血清总胆红素、直接胆红素、间接胆红素、谷氨酰转肽酶、碱性磷酸酶逐渐下降，术后12d夹闭T管，术后24d T管造影提示左、右肝管及胆总管下端通畅，无狭窄。

Four phenylalanine derivatives were synthesized with this approach. The condition of the condensation reaction was optimized. The side reaction of the Curtius reaction was studied and a urine by-product was isolated and characterized.b. Through the detailed study of the behavior of various N-acetyl phenylalanine methyl esters under the condition of the Bischler-Napieralski reaction, it was found for the first time that the formation of benzyl oxazole derivatives was a competitive approach with the normal B-N reaction.

一、基于Bischler-Napieralski反应设计了以苯丙氨酸衍生物为原料的路线，在这条路线的研究中，主要取得了以下结果：、建立了一条以芳香醛和丙二酸单甲酯为原料，通过缩合、氢化、Curtius等反应制备苯丙氨酸甲酯的通用合成路线，对其中的缩合反应条件及Curtius反应中的副反应进行了深入的研究，利用这条路线合成了四个芳环取代的苯丙氨酸单甲酯衍生物。

Among the economic crops, pachyrhizus leaf had the most remarkable treating effect, the COD treating capacity per day per unit area was 4.01g, that is, a 50% treating rate; the BOD treating capacity was 1.15 g, that is, a 35% treating rate; the TP treating capacity was 0.23 g, that is, a 16% treating rate; the TN treating capacity was 1.87 g, that is, a 74% treating rate; however, the treating effect decreased as the total amount of pollution entering this system increased by raising the water volume, which was mainly owing to the relatively short hydraulic retention time.

由水质试验结果显示，本系统所选用的作物处理生活污水成效极佳，优於一般湿地选用的植物，以及河滩地原生草种型态，其中以地瓜叶的处理成效最为显著，每日单位面积COD去除速率为4.01 g 、处理效率达50﹪；BOD去除速率为1.15 g 、处理效率达35﹪；TP去除速率为0.23 g 、处理效率达16﹪；TN去除速率为1.87 g 、处理效率74﹪，而以加大水量的方式，增加进入本系统之污染总量，其处理成效减低，主要原因受到水力停留时间较短影响，未来可以增加处理面积、水力停留时间加长、提高原水浓度为后续之研究方向，以达到增加本系统处理成效之目的。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了