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Viral vector mainly contain adenovirus, retrovirus,adeno-associated virus and so on, but it has potential danger of safety; it isrepeled by immune system when it is injected to organism for a greatimmunogenicity. An injection with adenovirus vector with highconcentration, it leads to serious inflammatory reaction of liver. Viralvector such as liposome and polycation are commonly used lately. But,liposome and polycation have low specificness and targetness of genetransfer tissue, have lower transfection efficiency and short period ofgene expression, for they can be phagocytized by endothelial system.

许多的载体,病毒载体和非病毒载体以前已广泛应用,病毒载体主要包括腺病毒,逆转录病毒,腺相关病毒等;但病毒载体在安全性方面存在潜在的危险;免疫原性比较强,注射到机体后很快会被机体的免疫系统排斥,当静脉注射高浓度的腺病毒载体会使肝脏发生严重的炎症反应;非病毒载体目前常用的有脂质体及多聚阳离子聚合物;但脂质体和阳离子聚合物介导基因转移缺乏组织的特异性和靶向性,转染效率较低且易被网状内皮系统吞噬,基因表达时间短;因此研制新型的非病毒载体已成为研究的热点,纳米颗粒具有小尺寸效应,表面效应,随着颗粒直径变小,比表面积将会显著增大,故具有很高的化学活性,因而纳米成为了最有应用前景的非病毒载体。

Results The positive cases of TTV-DNA were twenty-one in one hundred and thirty five aged viral hepatitis patients and the positive ratio was 15.6%; The TTV genic model was chief Ⅰ model (76.2%), The TTV singleness infection cases were two (9.5%) yet the superposable infection ratio was 90.5%, the difference had prominence.

结果 135例老年病毒性肝炎患者中TTV-DNA阳性者21例,阳性率为15.6%;TTV基因型主要为Ⅰ型(76.2%),TTV单独感染仅2例(9.5%),重叠感染率达90.5%,两者差异具显著性(P〈0.01)。

Objective To explore the diagnostic value of detecting respiratory syncytial virus-IgM for viral pneumonia in children.

目的探讨呼吸道合胞病毒-IgM抗体对婴幼儿病毒性肺炎的诊断价值。

Results Abnormal signal lesions were found in 47 patients with viral encephalitis, including multiple or single, symmetrical or asymmetrical large patch shape lesions, the located mainly in cortices, subcortical and basal ganglia and thalami. The lesions carried long T 1 and long T 2 on MRI. Enhanced MRI was performed in 22 cases, and demonstrated abnormal enhancement in 11 cases, including large patch or gyrus shape enhancement in 7 cases.

结果 病毒性脑炎脑内有多发或单发的对称或不对称大片状病灶,主要位于皮层、皮层下及基底节丘脑区,MRI呈长T1 长T2 信号,增强扫描22例,显示病灶强化者11例,其中呈大片状或脑回状强化者7例。

Incidence of human papillomavirus positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma?

瑞典斯德哥尔摩人乳头瘤病毒阳性的扁桃腺癌发病率研究:一种由病毒引起的流行性癌?

Infection of ESCs by the murine leukaemia viruses results in the normal establishment of integrated proviral DNA, but this DNA is then transcriptionally silenced, preventing further viral spread.

通过鼠类白血病病毒感染ESCs导致整合前病毒DNA的正常建立,但这种DNA而后变为转录沉默,阻止了病毒的进一步蔓延。

Recent studies have shown that a viral RNA polymerase known as PB2 is critical for efficient influenza transmissibility.

最近的研究表明,病毒的RNA聚合酶PB2在流感病毒有效传播中起关键作用。

By analyzing the outbreak in Mexico, early data on international spread, and viral genetic diversity, we make an early assessment of transmissibility and severity.

通过分析流感在墨西哥的爆发、国际蔓延的早期数据,及病毒的遗传多样性,我们做了传染性和严重性的早期评价。

This trichrome stain demonstrates the collapse of the liver parenchyma with viral hepatitis.

三色染色可见病毒性肝炎肝细胞的坏死。

In addition, there is a polyphenol substances "Anthocyanin Trimerization original" experiment confirmed that the strongest anti-viral effect, can effectively inhibit HIV-1 and human immune cell receptor combination, which can prevent the immune system against HIV.

此外,还有一种多酚物质&三聚原花青苷&,实验证实其抗病毒作用最强,能有效抑制 HIV-1 与人体免疫细胞受体的结合,从而可预防 HIV 侵害免疫系统。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。