查询词典 viral

Viral proteomics is helpful for understanding of the pathogenicity of the viruses, increasing the development of the new diagnosis methods and medicine, reinforcing the biodefense against the viral biological warfare agent.

病毒蛋白质组的研究有助于对病毒致病性的了解，加速新的诊断方法及治疗药物的研制，增强对病毒的生物防御。

Gosling new type viral enteritis is a new disease, whose epizootiology, the clinical symptoms and lesions are quite similar with those of gosling plague, and causes a serious economy lose for geese industry. Therefore, it is important and necessary to study the etiology, to develope a rapidly diagnosis technique, and to search the prevention and control measure of the disease.

雏鹅新型病毒性肠炎(gosling new type viral enteritis，GNTVE)是新近出现的一种在流行病学、临床症状和病理变化方面与小鹅瘟(gosling plague，GP)极其相似的传染病，它的出现给养鹅业造成了严重的经济损失。

Viral infection of the host cell may be switched on by the specific and stable combination of one or several viral envelope protein with one or several glycoprotein receptors available on the cell membrane, which is followed by viral pinocytosis or viral fusion with cell membrance, viral deenvelope, viral particle movement from cytoplasm towards nucleus and the viral gene passage.

病毒感染细胞可能是通过一个或几个病毒包膜蛋白与一个或多个细胞膜上的糖蛋白受体特异稳定地结合而启动，通过病毒胞饮作用或者病毒与胞膜融合、病毒脱包膜、病毒粒子从胞浆到胞核的运动和病毒基因通过核膜的传代将会发生；但参与这些动力过程相关的病毒、细胞结构和生化因子仍不清楚。

Duck viral enteritis, or duck plague, was caused by duck enteritis virus.DVE was an acute, heat and septicaemic contagious viral disease that naturally affecting birds of the order Anseriformes.

鸭病毒性肠炎(Duck viral enteritis，DVE)，又名鸭瘟(Duck plague，DP)，是由鸭肠炎病毒(Duck enteritis virus，DEV )引起的鸭、鹅及多种雁形目禽类的一种急性、热性、败血性传染病。

Uncovering the role of viral miRNAs in the pathopoiesis offers an immense opportunity not only to develope effective antiviral therapies,but also to identifying novel molecular targets for developing antiviral reagents.

揭示病毒miRNA（viral miRNA，vmiRNA）在致病过程中的作用不仅有助于开发有效的抗病毒疗法，而且能为开发抗病毒药物提供新的分子靶标。

Results On the basis of the percentage of GPI-anchored PLAP conversion,the sera GPI-PLD activities of total 172 patients,included 26 severe acute viral hepatitis as group A,29 liver cirrhosis as group B,32 chronic viral hepatitis as group C,55 mild acute viral hepatitis as group D,30 primary hepatocellular carcinoma as group E,were measured.As compared with 182 healthy presons as control group,the sera GPI-PLD activities of group A and B were significantly reduced;By contraries,the activities of group D and E were significantly raised.The sera GPI-PLD activities of group C compared with healthy control group were not significantly altered.However,when paired Q-test,the changes of serum GPI-PLD activity between all paired groups among this five groups were remarkable.

结果检测172例肝脏疾病患者(包括A组：26例急性重症病毒性肝炎；B组：29例肝硬化；C组：32例慢性病毒性肝炎；D组：55例急性非重症病毒性肝炎；E组：30例原发性肝癌)血清中GPI-PLD的活性，发现A、B两组患者的该酶活性较正常人(182名)显著性降低，而D、E两组则较正常人显著性增高，C组患者的酶活性与正常人无显著性差异，但A、B、C、D、E两组之间的酶活性水平改变却均有显著性。

Result: The thyrotoxic hepatic damnification on patients with hyperthyroidism is significant different compared with simple viral hepatitis and simple hyperthyroidism（P＜0.05）,the treatment of hyperthyroidism with viral hepatitis recovered liver function significantly, the T3、T4 in hyperthyroidism with viral hepatitis were higher than that in simple viral hepatitis or simple hyperthyroidism.

结果：甲亢合并病毒性肝炎肝功能损害比单纯甲亢及单纯病毒性肝炎都明显，且有显著性差异（P＜0.05），抗甲亢治疗能改善甲亢合并病毒性肝炎患者肝功能的恢复，甲亢合并病毒性肝炎比单纯甲亢血中T3、T4升高明显，导致甲亢加重。

With this in mind, the researchers then reanalysed data from knowingly HIV-positive heterosexual subjects in Uganda and Zambia who had HIV-negative sexual partners. Those with a viral load of one million particles per millilitre were more than ten times more likely to accidentally infect their partners each year than those with a load of one thousand.But when the researchers calculated the transmission potential over the entire predicted asymptomatic period, those with viral loads between ten thousand and a hundred thousand copies per millilitre of blood were the most likely to infect their partners. HIV-positive subjects with viral counts of 50,000 infected roughly twice as many people as those with counts of one million.

伦敦帝国学院流行病学家Christophe Fraser和他的同事对收集于1982年到1993年之间的100多例HIV阳性的男性同性恋者的数据进行分析，并结合分析来自乌干达和赞比亚的已知有HIV阴性性伴侣的HIV阳性异性恋受调查者的资料，他们发现中度病毒负荷而无症状的HIV携带者更易播散HIV，这是因为中度病毒负荷的HIV携带者的无症状期较长，而那些高病毒负荷而无症状的HIV携带者虽然传染性稍强，但其传染的持续时间却很短，并且在未经治疗的HIV携带者个体中中度病毒负荷是最常见的人群。

Abstract］ Objective For the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.The mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低pH常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低pH/巴氏消毒法；人纤维蛋白原、人凝血因子Ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。

Abstract］ objective for the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.methods aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with ph 4, human immunoglobulin and human hepatitis b immunoglobulin for intravenous injection with ph 4/pasteurization,treatment on human fibrinogen and human coagulation factor ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.the mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.results human albumin pasteurization inactivated vsv and sindbis virus,hrig low ph inactivated vsv and sindbis virus,hrig low ph inactivated hiv virus,ivig low ph/pasteurization inactivated hiv virus,ivig low ph inactivated hiv virus,hbig low ph/pasteurization inactivated vsv,sindbis and polio virus.conclusion suggestion about improvement on unreasonable parameter and standard of virus inactivation is made,cultivate target virus directly from final product by appropriate cell or method to monitoring viral safety of blood plasma product is advanced.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参数。方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低ph常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低ph/巴氏消毒法；人纤维蛋白原、人凝血因子ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。结果人血白蛋白巴氏灭活vsv与sindbis病毒，hrig低ph灭活vsv和sindbis病毒，hrig低ph灭活hiv病毒，ivig低ph/巴氏灭活hiv病毒，ivig低ph灭活hiv病毒，hbig低ph/巴氏灭活vsv、sindbis与polio病毒。结论建议改进病毒灭活验证标准与不合理的灭活参数；采用终产品样品通过合适细胞或方法直接培养目标病毒来有效监测血液制品的病毒安全性。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。