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In young human umbilical vein endothelial cells, human aortic endothelial cells, and human coronary artery endothelial cells, miR-217 induces a premature senescence-like phenotype and leads to an impairment in angiogenesis via inhibition of SirT1 and modulation of FoxO1 (forkhead box O1) and endothelial nitric oxide synthase acetylation.

在婴儿脐静脉内皮细胞、人类主动脉内皮细胞以及冠状动脉内皮细胞中，miR-217可以诱导这些细胞出现一种早衰样表型，进而通过抑制SirT1的表达、调控Fox01以及内皮细胞一氧化氮合酶的乙酰化来损伤新生血管的形成。

In this thesis, we define the notions of μ-semirings, A-semirings,*-μ-semirings and *-λ-semirings which extend the notions of inductive *-semirings. we also study the basic properties of these semirings and discuss the interrelation between them. Also, we discuss whether these semirings are closed for the construction of formal power series via a fixed point-theoretical viewpoint.

本文给出了归纳术*-半环及弱归纳*-半环概念的推广，即μ-半环、λ-半环、*-μ-半环以及*-λ-半环的定义；研究了这些半环的一些基本性质以及它们之间的相互关系；同时结合形式幂级数及不动点理论，讨论了这些半环关于形式幂级数构造的封闭性问题。

The model of the task system is set, and the model is described via formalization method.

建立了数控系统现场总线的任务模型及任务的形式化描述，设计了基于任务层次关系和截止时间特性的优先级策略，采用添加关系的方法将分时问题转换为一般问题，设计了现场总线调度算法。

In the presence of NaH and in DMF, the acyclic crown ethers 1a and 1b were synthesized by the reaction of di-or triethyleneglycol ditosylate and o-methoxymethoxybenzyl alcohol, which was obtained from salicylaldehyde via the protection of the hydroxyl group with chloromethyl methyl ether followed by the reduction of the formyl group with NaBH4. The hydrolysis of 1a and 1b with dilute hydrochloric acid provided the diphenolic type acyclic crown ethers 2a and 2b respectively in good yield.

将水杨醛与碱和氯甲基甲基醚反应，再经过NaBH4还原，即制得邻苯甲醇，然后将其在DMF中与NaH和二甘醇二对甲苯磺酸酯反应，得开链冠醚1a和1b.1a和1b经稀酸水解，即脱保护而分别生成新的酚型开链冠醚2a和2b。

Please do not forward the CD via express delivery to the clients directly, or at least, advise the clients well in advance.

请以后不要这样直接快递给客户或者你在快递给客户前请跟他们联系好！！

A new method of parameter estimation via Fourier series for time-delay bilinear systems is presented.

摘要本文提出了一种用Fourler级数来估计延时双线性系统模型参数的新方法。

We give some equivalent characterizations of Bloch type functions in term of fractional derivative, via studying the relative of growth of the different order fractional derivatives of holomorphic function, including the form of supremum and limit, the form of integral and Carleson measure, which are the generalizations of some known results in the unit disc and in the unit ball.

我们从研究全纯函数分数次导数的增长性入手，利用分数次导数给出了它的一类刻画，包括上确界和极限形式的特征，积分形式的特征以及Carleson测度形式的特征，推广了单位圆盘和单位球上一些已有的结论。

I'd like to book a ticket to Amsterdam via Frankfurt.

我想预订一张经由法兰克福到阿姆斯特丹的车票。

Free on Board point of shipment, freight prepaid via carrier of our choice and added to your invoice.

如果物质在运输过程中遗失或损坏，ATCC将免费更换。

All Materials are shipped Free on Board point of shipment, freight prepaid via carrier of our choice and added to your invoice.

如果物质在运输过程中遗失或损坏，ATCC将免费更换。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。