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Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶为起始原料，经醚化、硝基还原得到3-氯－4-（吡啶－2-甲氧基）苯胺，3-氯－4-（吡啶－2-甲氧基）苯胺与3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反应得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保护基后，与-4-二甲氨基－2-丁烯酰氯经酰化反应得到ner-atinib。

Objective :Provide image anatomy basis of the ultimate ethmoid sinus for the surgical approach via saddle area.

目的：为临床开展鞍区手术提供一组最后筛房的影像解剖资料。

This dissertation aims to: improvement in regularity of ladderlike polysiloxane through strong H-bonding template and"half-water-hydrolysis"methods; synthesis of several functional polysilsequioxane with ethoxyl, hydro and aminopropyl groups respectively; and the preparation of nanoporous film with good mechanic properties from ladderlike functional polysilsesquioxane with intermolecular porogen via micro-phase separation process.

本论文旨在利用强氢键模板作用和"半水水解-脱氯化氢缩聚"的改进方法，提高反应性的梯形聚硅氧烷的规整度；合成乙氧基封端、含氢基和氨丙基的几种功能性梯形聚硅氧烷；以及探索利用含分子内成孔剂的梯形聚倍半硅氧烷通过微相分离制备低介电常数二氧化硅纳米微孔膜。

This paper presents the synthesis of three kinds of amine such as 2-(methyl- sulonyl)ethylamine,3-propylamine and 2--ethylamine via three different methods.

本文采用三种不同的方法合成了2-乙胺，3-丙胺，2-乙胺等3个含砜基伯胺；还合成了3--x-吲哚甲酸甲酯(x=5，6，7)， E-4-喹啉甲醛肟，E-6-氟-2-吡啶甲醛肟等三类芳环甲醛肟，其中吲哚类和吡啶类化合物未见文献报道。

Nanocrystalline InOOH photocatalyst was synthesized from In(NO3)3 and ethylenediamine via a solvothermal method.

以硝酸铟作为前驱体，在蒸馏水和乙二胺的混合溶剂中制备出了InOOH纳米晶，详细地考察了反应溶剂及温度对终产物的影响。

A novel route for preparing poly(3-hexylthiophene)-based core shell like copolymer via click chemistry approach has been developed. First, regioregular ethynyl group ended poly(3-hexylthiophene)s (P3HT) were synthsized using a ethynyl-terminated Grignard reagent.

本篇文中，我们将多臂链星高分子与导电性高分子的末端基进改质，并用click chemistry 将者结合成为核壳型共聚合导电性高分子。

And some say that it was via Taenarum that Orpheus pursued his wife Eurydice when, bitten by a snake, she shared the common fate in journeying to the afterlife below. But others maintain that Orpheus\\\'s entrance was Aornum in Thesprotia.

而另外的一些人说，最著名的是奥费斯追随他被毒蛇攻击死去的妻子而进入冥界的入口TAENARUM，但是另外的人坚持说奥费斯的入口在基斯普罗西亚的AORNUM。

Gomez's arrival on the scene, via millions of mobile handsets worldwide, comes less than a year and a half after she met producer and songwriting collaborator Dave Stewart, best known for his tenure in the Eurythmics.

戈麦斯的到来，现场通过对全球数百万移动手机，在不到一年半之后，她会见了生产者和歌曲创作的合作者戴夫史都华，最佳艺术体操对他在任期内已知的。

Any fluids in the ear usually run out through the nose, via the Eustachian tube.

任何液体在耳，通常来说，通过鼻子，经咽鼓管。

Applications of castor oil as evacuant for afternoon IVP in bowel preparations can meet the image quality demand,thus provide an alternative for afternoon bowel preparations via IVP.

以蓖麻油为泻剂用于下午IVP的肠道准备，能达到影像质量所需要求，是下午进行IVP检查肠道准备的可选方法之一。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！