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Telmisartan is similar with benazepril in treatment of CHF, which is able to remodel the hypertrophied ventricle, and ameliorates the heart function.

替米沙坦和贝那普利具有相似的抗心室重构效应，替米沙坦的耐受性更好。替米沙坦；贝那普利；慢性充血性心力衰竭

Cozaar treatment not only decreased the hypertension but also remodel the hypertrophied ventricle.

科素亚能有效地控制血压的升高，对EH的LVH有逆转作用。

At the one-cell stage, each embryo was injected with gradient doses of 2-8ng MO. The control morpholino, was purchased from Gene-Tools.To test the knockdown effectiveness of the morpholino, the tbx2-EGFP (enhanced green fluorescent protein) construct was generated. And coinjection of morpholino with mRNA tests its specificity of the morpholino. Overexpression of tbx2 via mRNA microinjection helps us understand gaining function of tbx2. Results The tbx2-EGFP construct tests the knockdown effectiveness of the morpholino. Zebrafish embryos lacking tbx2 function have defects in cardiac contractility, rhythm and morphology in a dose-dependent manner. The embryos with c-MO are normal in development. Coinjection of morpholino with mRNA rescue the phenotype of tbx2 knocking down. The phenotypes include pericardial edema, hypogenetic ventricle, dilation of atria, arrhythmia, bradycardia, asystole, abnormal atrioventricular canal, aberrant valve and blood regurgitation.

结果荧光蛋白融合标记实验验证了tbx2-MO可以很好得阻抑斑马鱼胚胎tbx2的表达，tbx2-MO组胚胎在心脏收缩性、节律和形态学发生上出现了异常，心脏畸形随着注射剂量的增加而出现比较一致的表型，而c-MO组胚胎没有出现明显的畸形；tbx2-mRNA和tbx2-MO的共注射减少了tbx2-MO胚胎心脏畸形的发生率及减轻了心脏畸形的程度，验证了所设计合成的tbx2-MO对tbx2基因的抑制作用具有特异性；tbx2-MO组胚胎心脏缺陷包括心室发育不良、心房扩张、房室管和瓣膜异常以及心率缓慢、心律不齐、心脏停搏、血液返流等，并根据心脏发育异常的程度分为轻、中、重度畸形组tbx2-mRNA基因过表达胚胎没有见到心腔的形成。

Results: Thrombus within right ventricle and main pulmonary artery was detected in 6 patients, right atrium and RV enlargement was found in 19 patients, right ventricular hypokinesis was found in 21 patients, hypokinesis of interventricular septum was detected in 13 patients, MPA and right pulmonary arterial dilation was found in 22 patients, marked tricuspid regurgitation was detected in 23 patients, pulmonary hypertension was found in 23 patients.

右心异常改变者26例（包括超声直接检出血栓的6例），其中右房室增大19例；右室收缩功能减退21例；室间隔左移、左室短轴切面室间隔向左室膨突呈&D&型改变1例；室间隔运动幅度减低13例；主肺动脉及右肺动脉增宽22例；三尖瓣中量以上返流23例；肺动脉收缩压增高23例，范围在33~81mmHg (62.87±23.46 mmHg)，治疗后肺动脉压明显下降，范围在21~52 mmHg (34.26±13.52 mmHg)。

The findings of EMF on MRI were as follows:（1）RVEMF(6 cases): Thickening of endocardium with moderately high signal intensity, right ventricle was smaller and deformed, including obliteration of apex, shortening of inflow tract and dilatation of outflow tract, with hypokinetic contraction of the RV wall.

结果 EMF分为右室型、左室型和双室型三个亚型，MRI所见为：(1)右室型（6例）：右室心内膜显著增厚呈较高信号，右室腔缩小变形，流入道短缩，心尖闭塞而流出道扩张，室壁运动减弱，电影MRI（3例）显示有中至大量三尖瓣返流。

Early pulmonary stenosis is a possible cause because when the stenosis develops early, the right ventricle does not develop, and the right heart becomes hypoplastic.

早期肺动脉瓣狭窄是一种可能的原因，因为假如狭窄出现的很早，右心室就不能发育，从而出现发育不全。

The entire ventricle may become thicker (symmetric ventricular hypotrophy) or it may happen only at the bottom of the heart.

在这种情况下，有可能整个心室增厚（又称为&对称性心室发育障碍&），也可能进心脏底部增厚（又称为&心尖肥厚型心肌病&）。

Of 11 cases of edema had diffusive uneven SCC lesions. 1 case of edema had single midline oval lesion of splenium. The brain lesions of edema were incontinuous. In follow-up MRI of 5 cases of brain edema, the lesions were disappeared. In 3 cases of cerebral infarct, the lesions of SCC and brain were lateral distribution. 2 cases of hemorrhagic disease had diffusive uneven lesions in SCC and ventricle.

水肿性病变(n=11)中10例MRI表现为SCC弥漫不均匀病灶、1例为居中类圆形病灶，颅内病灶呈跳跃不对称分布，5例MRI复查病灶消失。3例脑梗塞SCC及脑内病灶呈偏侧分布，脑内散在病灶以患侧较多。2例SCC出血，SCC病灶弥漫不均匀，并见脑室内出血。

MATERIALS AND METHODS: hMSCs labeled with enhanced green fluorescent protein were transplanted into the lateral ventricle of neonatal mouse brain. At 0, 9 and 14 days post-transplantation, MICE were sacrificed and their brains were fixed with 4% paraformaldehyde. The engraftment of transplanted cells in coronal section of the recipient mouse brain was examined wider a fluorescent microscope. Indirected immunofluorescent staining was used to detect the expression of neural proteins of these grafted cells.

材料与方法：将标记绿色荧光蛋白的人骨髓间充质于细胞植入到新生3d的小鼠侧脑室中，分别于移植后0d，9d和14d处死受休鼠，取其脑组织，4%多聚甲醛固定后行冠状面冰冻切片，荧光显微镜下观察hMSCs的植入，激光共聚焦显微镜检测植入细胞神经特异性蛋白的表达，定位双重标记的植入细胞。

METHODS: Thirty six SD female rats were randomly separated into 3 groups (n=12 in each one) according to the infarction duration (1, 3, 28 d), which were randomly and evenly again separated into 2 subgroups: operated group and sham operated group. The levels of mRNA expression of ACE2 in the noninfarct and infract area of left ventricle 1, 3, 28 d after AMI were detected by RT PCR and analyzed semi quantitatively by image analysis system.

将36只SD雌性大鼠按时间段随机分为3组（每组12只），每组再随机分为假手术组、手术组2个亚组（每组6只），应用RT PCR方法检测大鼠AMI后1，3，28 d左心室梗死区及非梗死区心肌ACE2 mRNA的表达，并以图像分析系统对其进行半定量分析。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。