查询词典 variational formulation

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此，本文以难溶性的格列齐特为模型药物，在传统型推拉式渗透泵的基础上，设计并制备了双面打孔型推拉式渗透泵；通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面，对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察，同时，应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究；在此基础上，通·药学论文过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定，结合流体力学中的Poiseuille层流定律方程，对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此，本文以难溶性的格列齐特为模型药物，在传统型推拉式渗透泵的基础上，设计并制备了双面打孔型推拉式渗透泵；通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面，对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察，同时，应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究；在此基础上，通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定，结合流体力学中的Poiseuille层流定律方程，对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

Objective To establish HPLC-UV method for determination of glycyrrhizin acid in compound nasal spray of glycyrrhizin and flower flos magnoliae,the chief active ingredient of formulation,glycyrrhizin acid,and to observethe therapeutic effect of this formulation on guinea pig's hypersensitive rhinitis.Methods A compound nasal spray formulation was prepared using extracts of glycyrrhizin and measured by HPLC-UV method.Mobile phase conˉsisted of methanol,0.2mol/L ammonium acetate and glacial acetic acid（67:33:1,v/v）,analytical column was Zorbax ODS C 18 and wavelength250nm.

目的 建立测定复方甘草和辛夷喷雾剂含量的方法并观察该制剂对豚鼠超敏性鼻炎的疗效方法以甘草提取的甘草甜素和辛夷花蒸馏提取液主药制备成鼻用喷雾剂，用反相高效液相色谱法测定制剂中甘草酸含量，检测波长为250nm，Zorbax ODS C 18 分析柱，流动相为甲醇：0.2mol/L醋酸铵：冰醋酸（67：33：1）。

The following are main contents studied: A finite element method for Navier-Stokes equation with ALE formulation is considered and by combined with theNewmark method of numerical intergration a pressure correction scheme is obtained for the solution of the FE formulation of N-S equation. Because the incompressibility condition can be satisfied approximately in this scheme, the interpolation functions of elements can be equalorder for the velocity field and pressure field. In the ALE formulation the fluid-solid interaction analysis became a three-field coupling problem of the fluid field, the solid field and the fluid dynamic mesh. The properties and charactiristices of this three-field coupling problem are deeply discussed.

研究的主要内容有：主容器中流体大晃动是一种强非线性问题，文中研究了求解ALE描述的粘性流体N-S方程的有限元方法，以有利于大晃动自由液面的跟踪和流体大晃动中非线性现象的描述；并结合Newmark数值积分法推出了求解ALE型N-S方程的压力修正解法，由于这种解法可以近似满足不可压条件，因此可以采用速度场和压力场等阶插值的有限元离散格式，从而较好地解决了普遍采用的不等阶插值解法中，速度场和压力场数值精度不一致、程序编制不便等的不足。

To one kind of variational inequalities, some researchers give an alternating direction method, which solve a linear variational inequality and a system of nonlinear equations in each iteration.

针对一类变分不等式，有研究者给出了一种交替方向法，在每一步迭代中分别要求解一个线性变分不等式和一个非线性方程。

Lastly we made a comparison between variational method and finite element method on the lateral loaded behaviour of barrette pile group, and also proved variational method is a feasible and efficiency method.

论文在最后一章采用有限单元法和变分法对壁板桩水平承载特性进行了对比验证，证实了应用变分法分析壁板桩承载特性是一种可行和有效的研究方法。

According to that Caristi fixed point theorem is equivalent to Ekeland variational principle, we weaken the condition that the functional is bounded from below in Ekeland variational principle, then we enlarge the area of the applicable functionals.

鉴于Caristi不动点定理和Ekeland变分原理的等价性，我们对Ekeland变分原理中泛函的下方有界的要求作了相应的削弱，从而扩大了适用泛函的范围。

From the perspective of the variational discussion of Lagrange\'s contributions to the principles and analyzation of mechanics,the interaction between the calculus of variations and mechanics,especially the variational principles is made clear.

结合拉格朗日微积分代数化方案和18世纪可积性条件的研究，探讨了拉格朗日关于变分法基础研究的数学背景及相关工作；通过对《分析力学》中静力学约束平衡问题的细致考察，系统探讨了变分法中乘子法则的力学渊源、提出过程及意义。

In order to find the impact of cloud drift winds on variational data assimilation system and to provide reference for operational forecast of tropical cyclone, firstly errors of water vapor winds and infrared cloud drift winds in different levels have been analyzed in this paper; then, cloud drift winds of geostationary meteorological satellites-GMS 5 have been added in the GRAPES three-dimensional variational data assimilation system with radiosonde data.

首先分析了不同通道和层次的静止气象卫星云迹风产品的误差特征；然后，把云迹风资料放到GRAPES三维变分同化系统中进行同化，通过将不同观测类型资料的同化结果进行对比，探讨了红外通道和水汽通道云迹风资料对数值预报分析场的影响；最后，把同化后的分析场作为初始场，用WRF模式对2002年"森拉克"台风做24小时预报实验。

At present, although finite element methods is a kind of effective measures in analyzing metal plastically forming problems with friction, dynamic friction in the process of metal forming is substituted with static friction and constant frictional force as one of independent constraint conditions is transposed to equivalent node-load or FEM unit is divided into contact unit and inner unit in numerous studys and applications, so that it result in relative bad accuracy and awkward operation. These defects mostly attribute to the fact that FEM bases on the variational equality principles, however frictional constraint will actually result in variational inequality energy functional.

目前，应用于分析金属塑性成形的有限元法是一种有效的处理摩擦效应的定量计算方法，但是许多应用和研究是用常摩擦来代替金属塑性成形过程中的动态摩擦；把常摩擦力作为单独的约束条件移置到等效结点载荷上或把有限元单元划分成接触单元和内单元，这些将导致解的精度相对不高及实际操作不方便等一系列问题，产生这些不足的重要原因之一在于它的理论基础是变分等式原理。

Green function defined inphase space differs from one in coordinate space by its struc-ture which exhibits nonlocatity in coordinates and oscillatorybehavior with respect to momenta.

在相空间中定义的Green函数不同于通常坐标空间的Green函数，在结构上显示出对坐标的高度非局域性，而对动量则显示出振荡行为。

The upper front part of a saddle;a saddlebow.

前鞍桥马鞍前面的上部分；前鞍桥