查询词典 vanillic

It involved the converstion of vanillin into hydrazine (4) and the metalic reduction of hydrazine 4 into the intermediate vanillic amine.

以价廉易得的香草醛为起始原料，经过3步反应，高产率合成了酚羟基由对甲苯磺酰基保护的香草胺类化合物5。

Goal compound synthesis namely: Take the vanillic acid as outset raw material, obtains 4- hydroxyl - 3- anisole methyl formate with the methyl alcohol reflux conditions, then after the etherification, the nitration, the return to original state, the ring closure response obtains 6- methoxy - 7- animal pen oxygen radical kui zuo lin - 4- alkone, then passes through the chlorination, the substitution aniline, to escape responses again and so on animal pen oxygen radical, etherification to obtain the goal compound; The goal compound and the diethylamine had the amine substitution reaction to obtain TM1, namely 4- benzene amino - 6- methoxy - 7- [2- hydroxyl - 3-(N, N- two ethyl aminos) third oxygen radical] kui zuo lin; Through zuo has the etherification with the Austria niter to respond obtains TM2, namely 4- benzene amino - 6- methoxy - 7- [2- hydroxyl - 3-(2- methyl - 5- nitryl imidazole) third oxygen radical] kui zuo lin.

目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

The TLC of them were concordance.They presented the same color fluorescence in the corresponding position at the ultraviolet light(365nm). After the vanillic aldehyde sulphuric acid ethanol solution developed, violet color spots presented at the same place. Reference substance of Polysaccharide presented violet color ,but in the corresponding position the crude and the prepared didn't show the spots . It proves that the chemical constituents of Polygala Root may not have changed after stir-baked with honey.

生远志正丁醇部位色谱和蜜远志正丁醇部位色谱基本一致：紫外灯（365 nm）下二者在相应位置呈相同颜色荧光，香草醛硫酸乙醇溶液显色后二者在相应位置的几个斑点均呈紫罗兰色，且远志皂苷元对照品斑点呈紫罗兰色，而在与其相应位置生远志供试品和蜜远志供试品均未检视到相应斑点。

Results Eleven compounds were isolated and identified as:quercetin(1),kaempferol(2),quercitrin(3),protocatechuic acid(4),gallic acid(5),protocatechuic acid ethyl ester(6),ethyl gallate(7),vanillic acid(8),1,5,7-trihydroxyl-3methylan...

结果得到11个化合物，分别鉴定为：槲皮素(1)、山柰酚(2)、槲皮苷(3)、原儿茶酸(4)、没食子酸(5)、原儿茶酸乙酯(6)、没食子酸乙酯(7)、香草酸(8)、1，5，7-三羟基-3-甲基蒽醌(9)、琥珀酸(10)、5-羟甲基糠醛(11)。结论化合物6、7、9、11为首次从该属植物中分离得到。

Synthesis of target compounds namely: to vanillic acid as the starting material with methanol under reflux conditions for 4 - hydroxy -3 - p-methyl, then ether, and nitration, reduction, cyclization reaction 6 - methoxy -7 - benzyloxy-quinazoline -4 - one, and then by the chloride in place of aniline, benzyloxy-off, such as etherification reaction of the target compounds; target compounds with the second and third occurrence of substitution reactions of amines by the TM1, that is, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(N, N-diethyl amino) oxy c] quinazoline; with ether occurred Ornidazole reaction of TM2, namely, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(2 - methyl -5 - nitroimidazole) C oxy] quinazoline.

本论文以嘌呤类似物喹唑啉为母核，分别在其4位和7位引入结构多样的取代苯氨基和柔性侧链，设计了一系列4-取代苯胺基-6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉类化合物。目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Results Eleven compounds were purified and their structures were identified, they were identified as β-sitosterol, stigmasterol, nonacosanyl caffeate, daucosterol, betulinic acid, vanillic acid, inositol methyl ether, sucrose, soyasaponin Ⅰ, kaikasaponin Ⅲ, and dehy-drosoyasaponin Ⅰ.

结果 分得11个已知化合物，经鉴定为β-谷甾醇、豆甾醇、咖啡酸二十九醇酯、胡萝卜苷、白桦酸、香草酸、肌醇甲醚、蔗糖、soyasaponin Ⅰ、kaikasaponin Ⅲ和dehy-drosoyasaponin Ⅰ。

Sixteen compounds were separated from 80% ethanol extract of Plant A, they were:-lariciresinol,-isolariciresinol,-isolariciresinol 9-O-β-D-glucopyranoside, tanegoside B, apiginin, apigenin 7-O-β-D-glucoside, apigenin 7-O-β-neospheroside, quercetin 3-O-β-D-glucopyranoside, 1, 7-dihydroxy-3, 4-dimethoxyxanthone, 3-O- [α-L-rhamnopyranosyl (1-4 ] -β-D-glucopyranoside-(25S)-5β-spirostan-3β-ol , 3β-O-D-glucopyranoside quinovic acid, mangiferin , 3'-p-hydroxybenzoyl-mangiferin, physcion, benzenyl methanol β-D-glucopyranoside and Vanillic acid.

结果： 1。从植物A的80％乙醇提取物中共分离得到16个化合物，分别为：-落叶松脂醇、-异落叶松脂醇、异落叶松脂醇9-O-β-D-吡喃葡萄糖苷、tanegoside B、芹菜素、芹菜素7-O-β-葡萄糖苷、芹菜素7-O-β-新橙皮糖苷、槲皮素3-O-β-D-吡喃葡萄糖苷、1，7-二羟基-3，4-二甲氧基-口山酮、菝葜皂苷元-3-O-[α-L-吡喃鼠李糖基（1-4）]-β-D-吡喃葡萄糖苷、喹诺酸3β-O-D-葡萄糖苷、知母宁、3′-对羟基苯甲酸-知母宁、大黄素甲醚、苯甲醇-β-D-吡喃葡萄糖苷、香草酸。

The mycelial growth of Rhizoctonia solani was promoted by vanillic acid and syringic acid at levels of 0.1~1 mM/L, and it was inhibited remarkably by p-counaric acid of over 1mM/L and modestly by ferulic acid. The radial extent of mycelia of Fusarium solani was increased significantly by ferulic acid of 0.1~1 mM/L and limitedly by p-coumaric acid. vanillic acid had paradoxcial effects on the growth, positively at low levels and negtively at high levels, on which Syringic acid had a slight effect.

试验结果显示：浓度为0.1~1mM/L的丁香酸对西洋参立枯丝核菌菌丝生长具有促进作用，香草酸也有一定的促进作用，但不呈浓度效应，浓度在1mM/L以上的香豆酸对其有显著的抑制作用，阿魏酸也有一定抑制作用；对于西洋参根腐菌，阿魏酸对其生长有明显促进作用，香豆酸也有一定促进作用，香草酸表现为低浓度促进，高浓度抑制作用，0.1~1mM/L丁香酸对其生长基本无影响。

The results showed that in the growth period of R. glutinosa, soil ferulic acid, vanillic acid, and vanillin contents had a persistent increase, while β-hydroxybenzoic acid content increased first but decreased then. The addition of ferulic acid (8 μg·ml-1), vanillic acid (08 μg·ml-1), vanillin (12 μg·ml-1), and β-hydroxybenzoic acid (30 μg·ml-1) in water culture had stronger inhibitory effects on R. glutinosa root length, root mass, fresh plant mass, and plant height. Treating with test phenolic acids except β-hydroxybenzoic acid increased leaf chlorophyll content significantly, compared with the control. After treated with test phenolic acids, plant SOD and POD activities decreased after an initial increase, and plant malondialdehyde content increased. In the treatment of ferulic acid, root SOD and POD activities were the lowest, and roots were rotted and dead.

结果表明：阿魏酸、香草酸和香草醛含量在地黄生长期表现为持续增加，而对羟基苯甲酸含量先升高后降低；外加阿魏酸（8 μg·ml-1）、香草酸（0.8 μg·ml-1）、香草醛（1.2 μg·ml-1）和对羟基苯甲酸（3.0 μg·ml-1）对水培地黄根长、根质量、全株鲜质量和株高有较强的抑制作用；酚酸处理使地黄叶片叶绿素含量降低，除对羟基苯甲酸外差异性极显著；经过酚酸处理的地黄幼苗SOD和POD活性为先升高后下降，丙二醛含量升高，其中阿魏酸的处理使根中酶活性降至最低，根部腐烂死亡。

The detected phenolic, gallic acid was gradually increased with continuous cropping years increasing, vanillic was steady in soil of different continupus cropping years, ferulic acids had more content in soil of five-year continuous cotton cropping, but remarkably reduced with ten-year continuous cropping.7 It was found that the p-hydrobenzoic, vanillic, gallic acid and ferulic acids in different comentration inhibited/stimulated the spore germination and mycelium growth of cotton verticillium wilt.

没食子酸含量随着连作年限增加在土壤中逐渐增加，香草醛在不同连作年限土壤中含量较稳定，而阿魏酸连作5年土壤中含量最高，连作10年时显著下降。7不同浓度的对-羟基苯甲酸、阿魏酸、香草醛和没食子酸对棉花黄萎病病菌孢子萌发和菌丝生长产生促进或抑制的化感作用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。