查询词典 vaccines

It was the first of a series of vaccines and he's quite fine.

这是一个系列的第一个疫苗，他相当好。

In trimera model, irradiated LB373 cells and other recombinant vaccines could elicit cellular and humoral response, which suggests that this model could be applied for evaluating effects of all vaccines targeting to human in addition to various transgenic animals.

在Trimera模型中，用照射过的LB373细胞和各种基因疫苗免疫后能激发出mage-3抗原特异的细胞免疫应答和体液免疫应答，提示这种模型可以通用于基于人的各种疫苗免疫效果的评价，这将是各种转基因动物之外的另一个备选方案。

Then Vero cells were inoculated with a final cell density of 1×105/mL . After 7 days of culture, cell density can reach 6~7×106/mL, then rabies virus VaG strain was inoculated with a MOI of 0.01. After 24h inoculation, the cultured viruses were harvested continuously for 12 days. The titer of collected virus in the culture medium was about 6.0 to 8.5 logLD50/mL. From these collected viruses, vaccines were prepared through the steps of concentration, inactivation and purification, The quality of these vaccines meets "The Chinese Requirements for Biologics Year 2000".

在5L体积的生物反应器中，加入含10g/L微载体的199培养基，接种Vero细胞至细胞浓度达到1×105/mL，培养7d后细胞可生长至6~7×106/mL，然后以感染复数为0.01接种狂犬病毒VaG株，接毒后24h开始收获，连续收获12d左右，收获的病毒滴度范围在6.0~8.5logLD50/mL，收获的病毒原液经浓缩、灭活和纯化等步骤制备成疫苗，各项质量指标均达到《中国生物制品规程》2000年版要求。

The causative agent of the disease is an Corona virus, infectious bronchitis virus IBV）, classified as Corona .Present vaccines for IB are all modified live viruses derived either by sequential passage embrocated chicken eggs. As Immunogenicity of IBV is usually correlated with its virulence, almost all modified live IB vaccines remained insufficient attenuation and have shown a variety of side effects including spread of vaccine virus to no vaccinates, occurrence of long term "carrier" birds, and increasing virulence during in vivo passage.

目前国内外预防本病所用的疫苗大多数是弱毒疫苗，但现用弱毒疫苗都存在以下缺点：（1）与IBV强毒一样，其弱毒疫苗株也能引起潜伏感染，潜伏感染的鸡将终生带毒；（2）疫苗病毒可以由接种鸡传染给非接种鸡，在鸡群之间传播过程中毒力会返强，从而成为新的感染源；（3）传染性支气管炎病毒极易发生变异，且易成为病毒重组的供体和受体，给使用IB传统疫苗预防和根除IB带来极大的困难。

The results suggest that these six vaccines may be used in some emergency condition with proper order and immune period, but there may remain some risks in the multiple vaccines administration especially these with plague and anthrax vaccine.

结论出血热、霍乱、痢疾、钩体疫苗等疫苗在采用恰当的接种顺序和接种间隔的情况下可以联合使用，但是可能存在一定的风险，尤其在此基础上加入炭疽和鼠疫疫苗。

This review covered the following aspects in the development and application of CSF DNA vaccines: construction and evaluation, application of adjuvants, combination with other vaccines and the existing problems and solutions.

以下从猪瘟DNA疫苗的构建和评价、佐剂在猪瘟DNA疫苗中的应用、猪瘟DNA疫苗与其他疫苗的联合应用以及目前猪瘟DNA疫苗存在的问题和解决途径等方面做了比较全面的阐述。

The fusion DNA fragments of ag85b-mpb64 and ag85b-mpb64-esat-6 were obtained by PCR andSOE technique. Various DNA vaccines were constructed with the pcDNA3.1: fusion of two genes, and of three genes, bivalent combinations and trivalent combinations(pCA+pCM+pCE6). BALB/c mice were vaccinated with this DNA vaccines.The mice injected withBCG were positive control and the mice injected with pCDNA3.1 and PBS were negative control.The mice were immunized 3 times with 2-wk intervals. The animals in group BCG were only inoculatedsubcutaneously with 1×10~6 CFU BCG at initial vaccination. The serum IgG titers and IgG isotype weredetermined using iELISA coated with M. bovis PPD and rMAE protein expressed and depurated inprokaryotic expression system every week.

同样，利用PCR和SOE技术，获得牛分枝杆菌mpb64-ag85b和mpb64-ag85b-esat-6融合基因，以pCDNA3.1为载体构建了牛分枝杆菌多价组合和多基因融合DNA疫苗：二基因融合(pCDNA3.1-MPB64-Ag85B，简称pCMA)和三基因融合(pCDNA3.1-MPB64-Ag85B-ESAT-6，简称pCMAE)DNA疫苗；二价组合和三价组合(pCA+pCM+pCE6)DNA疫苗，免疫BALB／c小鼠，以牛分枝杆菌BCG免疫组为阳性对照，以pCDNA3.1及PBS免疫组为阴性对照，共免疫3次，每次间隔2周，BCG组仅初免时皮下免疫1次。1免后每周，以原核表达纯化的重组MPB64-Ag85B-ESAT-6蛋白和牛分枝杆菌PPD为包被抗原，以间接ELISA方法检测血清IgG水平及lgG亚类。

This paper introduced the kinds,the constitution of hyophilized heat-resisting protector of vaccines,and the application in vaccines for animals.

耐热冻干保护剂的组成和配方对冻干活疫苗的质量起着重要作用。

Many studies have shown thimerosal is safe , but some vocal groups have continued to lobby against its use and it has been removed from all childhood vaccines in the United States except for some influenza vaccines .

很多研究已经证实硫柳汞是安全的，但是一些组织继续去游说反对它的使用，而且在美国它已经不用于除了一些流感疫苗外的所有儿童疫苗。

In particular, the technology of the use of transgenic plants to produce human or animal therapeutic vaccines receives increasing atten-tion. Expressing vaccine candidates in vegetables and fruits open up a new avenue for producing oral/edible vaccines. Transgenic plant vaccine disquisitions exhibit a tempting latent exploiting foreground.

尤其是利用转基因植物技术生产植物疫苗的研究受到了广泛的关注，在转基因植物的可食用部位表达抗原生产人或动物治疗用重组蛋白和疫苗的技术为可食性疫苗的研制开辟了新途径，展现了诱人的开发前景。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。