查询词典 vaccine-therapy

The characterization of the fermental Toxigenic Pasteurella multocida (Pm 13-1) is studied according to the vaccine standard.

为检验该培养方法培养出的T+Pm是否符合对T+Pm制苗用菌液的生物学特性鉴定标准，分别取样作培养特性检验、菌体形态检验、糖发酵实验、T+Pm毒素产生的检测及荚膜型鉴定。

This study was aimed to construct and characterize Salmonella vaccine strain C500 expressing the recombinant Pasteurella multocida toxin antigen by the Asd+ balanced-lethal host-vector system.

本研究利用Asd+平衡致死系统构建表达巴氏杆菌毒素(Pasteurella multocida toxin， PMT)的重组猪霍乱沙门氏菌株，并对重组菌株的生物学特性进行比较研究。

Objective To study the efficacy of the TR/Patoc 1 slide agglutination assay for vaccination new pentavalent whole cell vaccine for leptospirosis.

目的 采用TR/Patoc 1玻片凝集试验评价钩端螺旋体疫苗免疫效果及应有价值。

Objective To study the efficacy of the TR/Patoc 1 slide agglutination say for vaccination new pentavalent whole cell vaccine for leptospirosis.

目的 采用TR/Patoc 1玻片凝集试验评价钩端螺旋体疫苗免疫效果及应有价值。

At the same time, Merck developed a pentavalent vaccine derived from five human-bovine reassortant strains that together would target the major strains of rotavirus.

此时，美国默克药厂研发了一种五价疫苗，由人及牛的五株病毒品系组成，可对付一些主要的轮状病毒品系。

FDA issued a Public Health Notification to inform health care providers and consumers about 28 post-marketing reports of intussusception following administration of Rotavirus, Live, Oral, Pentavalent vaccine.

药物不良反应工作小组药物安全警讯通告 96.02.FDA於2007年2月13日发出警讯，有28例使用口服轮状病毒疫苗(商品名为RotaTeq)后发生肠套叠的事件。肠套叠若发生肠子阻塞或扭转可能非常严重，甚至威胁生命。

objective to study the efficacy of the tr/patoc 1 slide agglutination assay for vaccination new pentavalent whole cell vaccine for leptospirosis.methods using tr/patoc 1 slide agglutination assay to detect the searial of serum specimens of 100 healthy people after vaccination for leptospirosis and comparing with the microsopic agglutination test.results both basic immunizaton and 20 days after the enhanced immunization,their positive seroconversion rates were higher than 90% in tr/patoc 1 slide agglutination assay,they were not signficantly different between slide agglutination assay and mat,the antibody titer was greatly lower in 90 days after basic immunization.conclusion the tr/patoc 1 slide agglutionation assay was one of useful assays in evaluation the lately immune efficency of leptospira vaccination.

目的 采用tr/patoc 1玻片凝集试验评价钩端螺旋体疫苗免疫效果及应有价值。方法采用tr/patoc 1玻片凝集试验检测100名健康人钩端螺旋体疫苗免疫后的血清抗体变化，并与显微镜凝集试验比较。结果无论是基础免疫还是加强免疫20？d后，玻凝试验抗体阳性率高达90%以上，与标准的显微镜凝集试验比较差异无统计学意义，玻片凝集试验检测的抗体持续时间较短，90？d后阳性率已大幅度降低，表明sat检测的抗体是早期抗体。结论 tr/patoc 1玻片凝集试验操作简易，可以作为基层卫生机构监测钩端螺旋体疫苗近期免疫效果的方法之一。

Comparison from the Germany isolate, phocine distemper virus type Ⅱ(PDV-2) and vaccine strain, the major difference is the long signal peptide domain while the mature protein exhibit high identity, and all of the 13 serine residues, four potential asparagine glycosylation sites and two hydrophobic regions supposed to affect the fusion function are completely identical. These data supports the view that F protein is more conservative than H protein in CDV.

三、犬瘟热病毒中国分离株囊膜糖蛋白基因免疫小鼠诱发的抗体应答经一系列步骤将CDV-YZ0101株的两囊膜糖蛋白基因定向导入真核表达载体pcDNA3.1中，DNA测序和酶切分析筛选阳性重组质粒克隆pcDNA-H和pcDNA-F，以重组质粒DNA和脂质体共转染COS-7细胞，用间接免疫荧光试验证实转染的COS-7细胞的胞浆中分别表达了CDV的H和F蛋白。

The results showed that the lower agglutination titers were observed at day 7 and up to higher levels over 〓 or 〓 at day 21 induced by the vaccine of recombinant pilin and the recombinant fused protein respectively. Above results suggested that the good immunogenicity of the two recombinant vaccines could match with both the D.

结果纤毛蛋白基因工程疫苗在免疫7天后，被免兔血清中出现抗E型节瘤拟杆菌凝集抗体，21天后被免兔的血清凝集效价达到〓，与节瘤拟杆菌菌体灭活疫苗，尤其与纤毛蛋白基因工程疫苗对照免疫试验相一致。

Nodosus pilin and the killed D. nodosus vaccines. It also means that the IL-2 in the fused Pilin-IL2 construct may also have a potential role in stimulating vaccine antigen .Key words: D. nodosus Recombinant Pilin gene Recombinant Ovine IL-2 gene Fused Pilin-IL2 gene

用Pilin-IL-2融合基因工程疫苗免疫健康家兔的初步免疫试验结果表明，2l天后产生较高的凝集效价，达到〓，甚至稍高于加佐剂的前三种疫苗，证明绵羊IL-2基因与Pilin基因融合后，可起到一定的免疫佐剂作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。