查询词典 vaccine-therapy

The efficacy of tumor vaccine is mainly affected by both heterogenicity of tumor cells and complexity of tumor antigens.

另 外肿瘤疫苗的效价也会受到肿瘤抗原成分的异质性及多样性所影响。

Taken together, the heterogonous boost combination provided superior protection by stronger CD(superscript 4+)(Th1) and CD(superscript 8+) T cell mediated immune response, which suggested that it will be a promising regimen for MTB vaccine development.

结果表明，DNA初发免疫、BCG加强免疫法能显著提高小鼠CD(上标 4+)，CD(上标 8+)T细胞介导的免疫应答，增强小鼠抗结核杆菌感染能力，是提高结核病疫苗免疫效果的新途径。

Results indicate that Lactobacillus casei possesses probiotic properties and can be used as oral vaccine carrier to deliver heterologous antigen.

结果表明：干酪乳杆菌符合益生菌的标准，可作为递呈疫苗抗原活菌载体。

To evaluate the efficacy of the recombinant fowlpox virus vaccine against the heterotype IBV, the chickens were challenged with the homotype IBV LX4 strain and the heterotype IBV LTJ95I strain after three weeks post vaccination. Antibodies against IBV were detected in vaccinated chickens one week post inoculation. The CD4+ T-lymphocytes in the peripheral blood increased rapidly in all groups challenged with IBV, except for the vaccinated group challenged by heterotype strain and the low level of CD4+ T-lymphocytes remained until end of the experiment. In all the groups, a high level of CD8+ T-lymphocytes only was observed in the vaccinated group after challenging with IBVhomotype strain. The morbidity and the mortality of this group were 21.43 % and 0 %, respectively, which showed significant difference with other groups. In addition, the lesions of chickens and virus shedding were less in the vaccinated group challenged by IBV homotype strain comparing with other groups, but there was no difference for the average body weight of chickens in all groups.

结果显示，重组疫苗接种1周后，免疫鸡产生抗IBV的抗体；而且外周血中CD4+和CD8+ T淋巴细胞的含量略高于非免疫对照组；攻毒后，异源强毒株攻毒的免疫组CD4+ T淋巴细胞呈下降趋势，并且该组低水平CD4+的状态一直持续到试验结束，而其他组CD4+ T淋巴细胞均迅速上升，峰值达到14.5 %；同源强毒株攻毒的免疫组CD8+ T淋巴细胞呈高水平的表达，而其他组攻毒后均无明显变化；保护率结果显示，同源强毒株攻毒免疫组的发病率和死亡率为21.43 %和0 %，与其他各组相比均有显著差异；另外同源强毒株攻毒的免疫组病理损伤与异源强毒株攻毒的试验组相比明显减轻，其排毒时间和排毒量也均有所减少；强毒攻毒后所有试验组体重无显著差异。

As an advocate for vaccines, she has received both travel expenses and honoraria from Merck, the developer of the chicken pox vaccine

在她的儿子死于水痘后，她支持疫苗，她并因此接受MERCK公司为她支付她的旅行费用和奖金。

Objective To construct humulus scandens pollen major allergen DNA vaccine pcDNA-LC2 and evaluate its immunogenicity.

目的 构建葎草花粉主要变应原核酸疫苗pcDNA-LC2并鉴定其免疫原性。

Humulus scandens grass pollen major allergen DNA vaccine pcDNA3.1-LC2 has been successfully constructed. It can be expressed in mice, produces humulus scandens grass pollen allergen specific antibody and has a good immunogenicity.

成功的构建了葎草花粉主要变应原核酸疫苗pcDNA3.1-LC2，pcDNA3.1-LC2可在小鼠体内表达，并能产生葎草花粉变应原特异性抗体，具有良好的免疫原性。

An Jiaotong University, Xi?an 710004, ChinaABSTRACT: Objective To construct humulus scandens pollen major allergen DNA vaccine pcDNA-LC2 and evaluate its immunogenicity.

目的 构建葎草花粉主要变应原核酸疫苗pcDNA-LC2并鉴定其免疫原性。

Objective: To investigate the situation of TCR Vβ gene repertoire and clonal expansion in peripheral blood T cells from patients with acute lymphoblastic leukemia and T cell strains, and analysis the expressive characters of TCR V β gene idiotype. To develop the anti-lymphoblastic leukemia TCR idiotypic DNA vaccine.

目的：了解淋巴细胞白血病及T细胞株的TCRVβ基因谱系及其克隆性增殖情况，分析TCR Vβ基因独特型表达的特点，并构建具有抗淋巴细胞白血病作用的TCR独特型DNA疫苗。

Pioneering work by Cohen and coworkers about T cell vaccination in the experimental autoimmune disease, has showed that the establishment of immune response against T cell vaccine, such as anti-idiotype T cells or anti -idiotype antibody, by the way of the upregulation of immune networks, and subsequently functional depression of autoimmune to self-antigen were made by vaccining mice or rate with the attenuated autoreactive T cells .

从研究TCV在防治自身免疫性疾病中的作用机制表明，人为的TCV免疫，建立了拮抗T细胞的免疫应答，使免疫网络产生上调作用，抑制了原有的或即将出现的相关T细胞的功能，由此推测，是否能够把同种反应性T细胞作为TCV，来建立抗同种免疫反应的内环境，诱导抗原特异性的同种免疫耐受或免疫低反应性。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。