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Abstract] Objective To discuss the safety and immunogenicity of trivalent split influenza virus vaccine.

目的 探讨流行性感冒病毒裂解疫苗的临床安全性与免疫效果。

Objective To screen the protective antigen of G.intestinalis and set the foundation for immune reseach of vaccine. Methods The trophozoite antigens were obtained with in vitro culture system of Giardia lamblia Stile. After further separation, purification and activity verification, the antigens were used to immunize the BALB/C mice divided into different groups,then indexes associated with immunity were determined. Through challenge infection, the most protective antigenic component of G.intestinalis were selected based on its anti-infection ability.

目的 筛选蓝氏贾第鞭毛虫的保护性抗原,免疫疫苗的研制奠定基础方法利用已建立的蓝氏贾第鞭毛虫滋养体体外培养系统,获取滋养体抗原,并进步分离、纯化、活性鉴定;然后分组免疫小鼠,检测相关免疫指标;再行攻击感染试验,视其抗感染能力,筛选出保护性强的抗原组分。

The antigenic reservoir produced a protective rate as high as 80%, which provides a way for developing new vaccine of Trypanosome evansi.

该抗原库的最佳免疫保护率达到 80%以上,它的建立为伊氏锥虫疫苗的研制开辟了一条新的途径。

Examples of this type of vaccine s are those that fight influenza, typhoid fever, and cholera.

这类疫苗有抗流感、伤寒和霍乱的疫苗。

Objective To explore the effect of CpG-ODN on cellular immune response induced by typhoid Ty21a vaccine.

目的 探讨CpG-ODN对伤寒Ty2la疫苗诱导的细胞免疫应答的作用。

The diagnosed JE cases accounted for 71.88%-74.90% in Guizhou province. It should further strengthen JE surveillance system, enhance laboratory diagnosis technique so as to diagnize effectivly JE cases, and put the emphasis on the immunization of JE vaccine to the population of under 15 years old.

应进一步加强乙脑专项监测和提高实验室诊断技术,使非乙脑报告病例得到明确诊断;继续对15岁以下儿童实施乙脑疫苗预防接种为主的综合防治措施。

RESULTS: Serum titer of antibody against MG7-Ag was significantly higher in mice immunized with the vaccine than that in control groups (0.841 vs 0.347, P.01; 0.841 vs 0.298, P.01), while in vitro unprimed proliferation assay of the spleenocytes showed no statistical difference between those three groups.

结果免疫组小鼠的IgG抗体水平明显提高,滴度为1:100;NK细胞杀伤活性和T细胞增殖活性也明显增强,其中NK细胞杀伤活性为85%±7%,T细胞增殖指数为2.83,与对照组相比差异有统计学意义(P.05)。

The discovery of a vaccine was the turning point in the fight against smallpox.

牛痘苗的发现是根治天花的关键。

If cells were truly understood, that process might speed up to the point where the vaccine was ready in time to do something useful.

如果我们对细胞有彻底的了解,疫苗的研制过程也许会加速,在我们需要的时候能及时的发挥作用。

A flow of vaccine from an investment point of view, Sea King bio also need to GMP certification, companies benefit from the existence of the degree of uncertainty.

从甲流疫苗投资的角度来看,海王生物还需要GMP认证,公司受益程度存在着不确定性。

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