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The team developed a siRNA product that specifically blocks the transcription of the gene that codes for IL-8, thereby blocking production of this protein, and encases it in a liposome delivery system. In mouse studies, this product showed activity against 2 ovarian cancer cell lines, both when used alone and when used in combination with docetaxel. In addition, the mouse studies revealed that the product was decreasing tumor growth through anti-angiogenic mechanisms — the treated tumors showed a lower microvessel density, the researchers report. This product was "highly effective in our preclinical studies and may merit clinical development," they write. However, they also caution that the cell lines used to create the mouse models might not accurately reflect the heterogeneity seen in human tumors.

该团队发展一种siRNA产品,特别阻断IL-8的基因转译密码,因此阻断此一蛋白质之产生,且将它包入一个微脂粒传递系统;在老鼠研究中,不论单独使用或者和docetaxel并用,此产品显示对两种卵巢癌细胞线有活性;此外,老鼠研究发现此产品可透过抗血管新生机转减少肿瘤生长—报告指出,治疗的肿瘤显示较少的微血管密度,此产品在我们的临床前研究中相当有效,值得临床发展;不过,他们也表示,所用的老鼠研究中的细胞线可能无法精准反应人类肿瘤的异质性。

The team developed a siRNA product that specifically blocks the transcription of the gene that codes for IL-8, thereby blocking production of this protein, and encases it in a liposome delivery system. In mouse studies, this product showed activity against 2 ovarian cancer cell lines, both when used alone and when used in combination with docetaxel. In addition, the mouse studies revealed that the product was decreasing tumor growth through anti-angiogenic mechanisms — the treated tumors showed a lower microvessel density, the researchers report. This product was \"highly effective in our preclinical studies and may merit clinical development,\" they write. However, they also caution that the cell lines used to create the mouse models might not accurately reflect the heterogeneity seen in human tumors.

该团队发展一种siRNA產品,特别阻断IL-8的基因转译密码,因此阻断此一蛋白质之產生,且将它包入一个微脂粒传递系统;在老鼠研究中,不论单独使用或者和docetaxel併用,此產品显示对两种卵巢癌细胞线有活性;此外,老鼠研究发现此產品可透过抗血管新生机转减少肿瘤生长—报告指出,治疗的肿瘤显示较少的微血管密度,此產品在我们的临床前研究中相当有效,值得临床发展;不过,他们也表示,所用的老鼠研究中的细胞线可能无法精準反应人类肿瘤的异质性。

For example, if the two methods used are the Playfair cipher and simple columnar transposition, if transposition is used first, the Playfair cipher can still be attacked, because it takes each input letter to a limited number of substitutes; if the Playfair cipher is used first, multiple anagramming, although now much more difficult, is still possible because a text enciphered by Playfair still has digraph frequencies marked well enough to allow a correct match to be detected.

例如,如果这两种方法用的是playfair密码和简单的柱状移位,如果移位是用第一, playfair密码仍然可以被攻击,因为它需要每个输入信有限数量的代用品;如果playfair密码是用来首先,多重anagramming ,虽然现在困难得多,仍然有可能因为一个文本加密由playfair仍然有向图的频率明显做得不够好,让一个正确的匹配,以进行检测。

The technique of multivariate statistical analysis is used to study the driving adaptability for drivers in mechanism of faming. The principal component analysis is used to found the evaluated index system for the driving adaptability. The cluster analysis is used to group drivers

依据主成分分析方法建立了农机驾驶员职业适应性的评价指标体系;运用动态聚类分析方法对驾驶员职业适应性的优劣进行了分组;使用判别分析方法来确定驾驶员的分类归属。

A new method was given for determining the eye movement in a video-oculography system, where the centroid method was used to get the initial position of eye center, a edge filter was used to obtain all the boundary of the pupil, then a ellipse fatting was used to determine the accurate position of the eye center.

本文提出了一种全自动确定眼动平动的新方法。首先用形心法确定瞳孔的初始位置,再用亚像素边界算子提取瞳孔边界,并用带自动优化功能的椭圆拟合最终确定瞳孔的精确位置。

Different object functions are used to accomplish the optimum assay of the North mainline. The TGNET software has been used to modeling and calibration assay of several mainlines. It has also been used to accomplish the hydraulic attestation of the optimum calculation results.

针对北干线等管线,以不同目标函数进行优化分析;利用TGNET软件对几条干线进行模拟及能力标定分析,并对优化计算结果进行水力验证。

We had been used to arbitrary on the net absurd to be, be used to everywhere fill water, be used to annoying fling abuses, this one practice of skyline is the hands or feet that manacled us undoubtedly.

我们已经习惯了在网上恣意妄为,习惯于四处灌水,习惯于骚扰谩骂,天边的这一做法无疑是束缚住了我们的手脚。

If the absorbance of the three process colors were correctly matched to the spectral response of the eye,printing cyan,magenta,and yellow on top of each other would absorb all of the additive primariesto produce black.In practice,overprinting these three colors creates a dark brown,so to enable a wider range of densities to be printed a black ink must also be used.The black also enhances the edges of an image and reduces the amount of expensive colored inks that need to be used.The four colors cyan,magenta,yellow,and black are often abbreviated as CMYK,with the last letter of the word black used instead of the first to avoid confusion with blue.Many people in the praphic arts industry refer to cyan and magenta as"process blue"and"process red"(or,confusingly,as just blue and red).As well as any pigment that may be present,substrates have other properties that affect color appearance.

如果吸收的三色过程中,正确匹配的光谱响应的眼睛,印刷青色,洋红,黄色加上对方将吸收所有的添加剂初选出示black.in实践,overprinting这三种颜色创造了暗褐色,为了使更广泛的密度须印黑色油墨,还必须 used.the黑色也提升了可贵的图像,并减少了昂贵的彩色墨水的需要状四色青色,品红,黄色和黑色往往简称为cmyk,最后信件的文字用黑色代替对第一,为了避免引起混乱与blue.many人民在praphic艺术产业是指青色,洋红&进程蓝&和&过程红&(或笼统,只是蓝色和红色)。

The surprisingly fast animal was directed by picadors to attack Anakin Skywalker. Skywalker used his Jedi agility to leap upon the beast, and used the reek's sheer muscle-power to break the chains that bound him. Skywalker was able to momentarily calm the reek, and used the massive horned creature as a mount while chaos reigned within the arena.

这只行动惊人地快速的动物在吉诺西斯骑士的指挥下前去攻击安纳金天行者,天行者以敏捷的绝地身手跳到它身上,并利用里克兽的力量来破坏绑著他的锁链,然后天行者短暂地使它平静下来,并在行刑场中一片混乱时利用这只有角巨兽当座骑。

Were used as parents to produce a F2 population consisting of 120 individual plants, which were used to construct a molecular linkage map. On the basis of observing the qualitative and quantative traits of the map population, Two types of DNA molecular marker methods, simple sequence repeals and amplified fragment length polymorphism, were used to construct a linkage map of molecular markers and to map genes of agronomic characters.

多标记基因系T582和T586为亲本,构建了一个由120个单株组成的用于分子标记图谱构建的F_2作图群体,在考察和分析亲本、F_1和F_2群体质量性状和数量性状的基础上,利用SSR和AFLP分析技术,首先对各群体进行DNA分子标记的多态性分析,然后对显示多念性的标记进行连锁分析、图谱构建和农艺性状基因的定位。

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推荐网络例句

No complex distressful things on your mind but only our love and care for each other.

无复杂痛苦的事情,对你的心,但只有我们的爱和照顾对方。

At first light, on his own initiative, Vick located the enemy emplacements andfired on them, using 15 rounds.

破晓时分,维克主动地去查找敌军的炮位并向它们开火,打了15发弹药。

He pioneered the use of the vibraphone as a jazz instrument single-handedly popularized its use.

他的作品受到了从总统到爵士乐评论家的赞赏和公众的支持。