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Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

This system programmed can he used in designing cushion, fiberboard box and tray of products, and it can also he used in combining and optimizing design schemes.

设计的集成化运输包装系统可以完成产品的缓冲设计、纸箱设计和托盘设计，并对方案进行组合、优化和优选。

Numerical method was used to calculate the flow field in three-phase fluidized bed, and to find the better arrangement of rectifying plate. The Discrete Phase Model was used to track the particles track and analyse the influence of structure parameters and operating parameters on dust-collection efficiency. The experimental results coincided with the calculation result.

利用数值计算的方法模拟计算三相流化床塔内流场分布，探求三相流化床的设计参数和运行参数对流场分布的影响，并找出优化整流板布置的方法；利用离散相模型模拟计算粉尘粒子运动轨迹，分析设计参数和运行参数对除尘效率的影响，并与实际工程测试结果比较，结果是两者基本吻合。

As-grown ZnO:N material was used as active channel layer and Si3N4 was used as gate insulator to fabricate thin-film transistor. The fabricated devices on glasses demonstrate typical field effect transistor characteristics.

接着我们把掺氮ZnO薄膜作为沟道层材料，用Si3N4做栅绝缘层在非晶玻璃上制备了ZnO基薄膜晶体管，ZnO-TFT器件表现出了典型的场效应晶体管的输出特性。

Michelle is a little shy.I used to be that way when I was her age.I used to be that way when I was her age.We had a summer house on Fire Island.

如果因您不良评论或重复评论导致评论被删，您将会被扣掉一定数额的金币。

Production of fire clay declined by 19.5% to 383,000 t valued at $5.97 million, with 88,200 t used in heavy clay products and lightweight aggregates (-12.7% compared to 2000) and 277,000 t used in firebrick, block, shapes and other refractories (-20.4%).

耐火粘土产量也下降至38.3万吨，比2000年下降了19.5%，产值约597万美元。其中有88200吨用于重粘土产品和轻质骨料生产（下降了12.7%），27.7万吨用于耐火砖，砌块，异形砖和其他耐火材料，下降20.4%。

If it is fishing, half-water fishing on the float hanging use, fishing at the end of the sink to the bottom using (luring the fish have a tether device the holes); also be used for hanging nets, wire mesh, pull net, seine net, maze, water fish cages in the cage such as fishing nets can be used, generally can be placed at the end of the central network, or hang around on the Internet, or on the network.

如果是钓鱼，半水钓就浮球吊着用，钓底就沉底使用；也可以用于挂网、丝网、拉网、罾网、迷魂阵、水地笼等鱼网鱼笼都可以使用，一般可以放在网底中央或者挂在网上或者放在网附近。

He TP flag is used to allow the user to find only those stations that regularly broadcast traffic bulletins whereas the TA flag is used to stop the tape or raise the volume during a traffic bulletin.

P 旗子被使用允许用户发现唯一通常播放交通公报的那些驻地但是TA 旗子被使用停止磁带或培养容量在交通公报期间。

In this thesis, combinations of the IRT, BLOOM education classification system theory and the concept of fitness in accordance with the concept of the theory are used to develop a teaching intelligent test system. Flash animation will be used to enhance student's learning. We also use the automatic mechanisms to create questions, and generate the subject questions so that the development time will be saved.

而本论文结合了试题反应理论、BLOOM教育分类系统、适性理论的概念与依循理论的概念，开发出智慧型教学测验系统，并结合了Flash动画增进学生学习效果；在题库的设计上，则是采用自动造题机制，来产生测验的题目，如此一来，可以节省题目的开发时间。

Vacuum valve types: solenoid valve, butterfly valve, valve, flashboard valve, damper valve, fine-tuning valve, ball valve vacuum, vacuum regulating valve and so on, were used to drive manual, electric, pneumatic, electro-magnetic action, etc., caliber from 0.8-1200, leakage rate from 6.7 10-2-1.3 10-7PaL / S, the application of temperature -30 ~+400 , apply pressure range 1 105-1 10-7Pa (low, high, ultra-high vacuum system), is widely used in aerospace, electronics, energy, environmental protection, food, machinery, refrigeration, medicine, scientific research and other fields, the vacuum in the domestic industries enjoy a high reputation.

真空阀门类：电磁阀、蝶阀、隔膜阀、插板阀、挡板阀、微调阀、真空球阀、真空调节阀等，驱动装置分别采用手动、电动、气动、电磁动等方式，口径从0.8-1200、漏率从6.7×10-2—1.3×10-7PaL/S，适用温度-30℃～+400℃，适用压力范围1×105—1×10-7Pa，广泛应用于航天、电子、能源、环保、食品、机械、制冷、医药、科研等各领域，在国内真空行业享有较高的声誉。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。