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To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray.
为了阐明中枢神经系统损伤后神经可塑性的分子机制,本实验探索了多种方法,包括传统差异筛库、传统cDNA array和cDNA microarray,对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。
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To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray. Of 2300 cDNA clones from low-abundance rat brain cDNA bank, 6 were identified as differentially expressed genes/ESTs in the hippocampus 35 days after lesion, in which none was confirmed by Northern blot. Of 8000 cDNA elements, custom cDNA array identified 47 as differentially expressed genes/ESTs with above 3-fold changes in the hippocampus 35 days after lesion, in which 25 were up-regulated and 22 down-regulated.
中文题名去传入海马的差异表达基因筛选和Cystatin C表达副题名外文题名 Screening of the differentially expressed genes and cystatin C expression in the deafferented hippocampus 论文作者应国新导师周长福研究员学科专业神经生物学研究领域\研究方向学位级别博士学位授予单位中国科学院上海生命科学研究院学位授予日期2002 论文页码总数121页关键词海马星型胶质细胞 Cystatin C 基因表达去神经海马馆藏号BSLW /2003 /Q42 /27 为了阐明中枢神经系统损伤后神经可塑性的分子机制,本实验探索了多种方法,包括传统差异筛库、传统cDNA array和cDNA microarray,对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。
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After some generations the population diversity would be greatly reduced and the algorithm might lead to a premature convergence to a local optimum. To circumvent these shortcomings, the chaotic dynamic system is introduced in the studies of chemometric algorithms. The chaotic mapping itself is very sensitive to the initial state in a manner similar to the statistical randomness but with its underlying patterns appearing to be phantasmagoric in a deterministic style.
神经网络是一个优异的非线性建模工具,但其突出的缺点就是潜在的预收敛到局部最优点或过拟合导致的错误预报模式;遗传算法用于优化过程其目的是为了避免陷入局部最优点,但事实上由于在传统遗传算法的进化过程中只有少数最好的成员被保留下来用于产生子代成员,经过一定代数的进化后群体成员的多样性就会显著下降,也很可能过早收敛到局部最优点。
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Al becomes a major factor limiting crop growth and yield when solubilized in acid soils to phytotoxic species Al3+, but the mechanism underlying the Al toxicity remains largely unknown.
铝毒是酸性土壤中植物生长发育的主要限制因子,但目前关于铝毒的生理学机制并不很清楚;另外,关于园林花卉的铝毒害研究尚未见报道。
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Neuralgia, costochondritis, underlying pleuritic lesions, or arthritis of the thoracic spine
膜炎损伤或胸椎关节炎引起的胸壁痛可类似于乳腺良性疾病。
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Pleurisy, also known as pleuritis, is a serious condition that occurs when the two thin membranes lining the lungs are infected, usually as a result of a severe chest infection, pneumonia, or some other underlying lung disease.
性胸膜炎,也称为性胸膜炎,是一个严重的状况时,所发生的两薄膜衬砌肺部感染,通常是由于严重的胸部感染,肺炎,或其他一些潜在的肺部疾病。
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An alternative theory postulated by Schneider et al (1) and expanded on by Dernevik and colleagues (2) suggests that the event underlying round atelectasis is a local pleuritis that is caused by irritants such as asbestos.
另外一个理论是由Schneider等提出,并由Dernevik和他同事完善,认为球形肺不张基础是如石棉等刺激引起的局部胸膜炎。
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Part I: Angiotension I Converting Enzyme Gene Polymorphism in Chinese Patients With Obstructive Sleep Apnea SyndromeObjective Obstructive sleep apnea syndrome is a complex, multifactorial, and polygenetic disease that is thought to result from an interaction between an underlying genetic background and several environmental factors.
第一部分:血管紧张素转化酶基因多态性与阻塞性睡眠呼吸暂停综合征阻塞性睡眠呼吸暂停综合征是一种复杂的多因素和多基因疾患,是由于潜在的遗传背景和外在因素作用的结果。
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Results Among the 48 patients infected with PM, 38 were respiratory infection. ICU was the main endemic area, accounting for 29.2%, followed by departments of respirology and neurosurgery. Of the 48 patients, 41 suffered various underlying diseases, and 38 with polymicrobial infection.
结果 48例嗜麦芽假单胞菌感染者中呼吸道感染最多,占38例;病区分布以重症监护室最多,占29.2%,其次为呼吸内科、神经外科。48例嗜麦芽假单胞菌感染病人多具有多种基础疾病及多菌种感染,其中有两种以上疾病者41例,多菌种感染者38例。
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Even in the Fifth Symphony, with its polytonal clashes, there is never any doubt about the underlying tonality.
试译: 甚至在《第五交响曲》中,尽管存在多调性碰撞,但其中处于支撑地位的调性并不含糊。
- 相关中文对照歌词
- Underlying Depression
- 推荐网络例句
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This one mode pays close attention to network credence foundation of the businessman very much.
这一模式非常关注商人的网络信用基础。
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Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.
扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。
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There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.
双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。