查询词典 tyrosine

Objective To investigate the effects of Shp-2 tyrosine phosphatase activity on unlimited proliferation of leukemia cells.

目的 研究Shp-2酪氨酸蛋白磷酸酶对白血病细胞恶性增殖的影响。

In the present study, we examined the role of c-Cbl tyrosine phosphorylation in vascular injury.

在此研究中，我们观察了c-Cbl酪氨酸磷酸化在血管损伤中的作用。

Thus, in the following studies, we pay much attention on the role of phosphorylation of tyrosine.

因此，在深入模拟计算过程中，我们重点考虑了酪氨酸磷酸化修饰的作用。

Most protein tyrosine phosphorylation in suspended tumor cells was decreased.

大多数蛋白酪氨酸磷酸化的水平在悬浮培养的乳腺癌细胞中是下降的。

Nuclear translocation of tyrosine-phosphorylated STAT3 was also not detected in the uteri on day 4 of pseudopregnancy and under delayed implantation.

在假孕第4天的子宫和延迟着床的子宫中未发现酪氨酸磷酸化STAT3的核转位现象。

The characteristics of quinazoline epidermal growth factor receptor inhibitors were briefly described in this paper, and the mechanism of receptor-tyrosine kinase inhibitor was also introduced. The synthesis of this kind of new compound was studied, and the synthetic route was redesigned and the method was modified.

本论文简述了受体酪氨酸激酶小分子抑制剂的发展概况，详细介绍了新型喹唑啉类表皮生长因子受体抑制剂，着重研究了该类化合物的合成，设计并打通了合成路线，同时又合成了25个新化合物。

Objective: through various chemical synthesis target compounds 4 -- 6 - the - 7 -(2 - hydroxyl replace c oxygen radicals) quinazoline compounds were synthesized and the structure of the modified, so as to get high epidermal growth factor receptor tyrosine kinase inhibitor.

目的：通过各种化学合成方法完成目标化合物4--6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉的合成并对目标化合物进行结构修饰，以期获得高活性的表皮生长因子受体酪氨酸激酶抑制剂。

Special attention was directed toward finding inhibitors selective against KDR tyrosine kinase in order to ensure that the in vivo profile of a specific Src inhibitor could be determined. The 4-aminobenzodioxole quinazoline series gave compounds with excellent potency and selectivity.

一直以来，人们为了确保能够在体内测定Src酶专属性抑制剂的特性，把研究焦点放在对KDR酪氨酸激酶选择性的抑制剂的寻找上。4-氨基苯并间二氧五环喹唑啉系列化合物具有极好的效力和选择性。

Protein tyrosine phosphatase 1B (PTP1B) is the key phosphatases dephosphorylating the Y1162 site of insulin receptor.

在胰岛素通路中进行信号负调节的PTP1B是一个具有使胰岛素受体去磷酸化作用的磷酸酯酶，是目前确证的治疗II型糖尿病的重要分子靶点。

Hereinto, Tyr-Fal was prepared from L-tyrosine and formaldehyde under alkaline conditions.Firstly, a new multi-functional film with well-defined layered structure was fabricated from Tyr-Fal and PEI via LbL method. Experiment revealed that this Tyr-Fal/PEI multilayer film emit yellow fluorescence under UV radiation. The ability of the Tyr-Fal/PEI multilayer film for adsorbing rosaniline improved after UV-exposed, which can be used in preparing micropattern.

然后以Tyr-Fal为结构单元，通过静电力自组装构筑了两种功能性的酪氨酸基多层膜：(1)利用Tyr-Fal与聚乙烯亚胺间的静电力构筑了结构稳定、有序、能在紫外光照射下发出耀眼黄色荧光的聚乙烯亚胺/酪氨酸缩甲醛超薄膜。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。