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The typical apoptotic morphological features appeared in MUTZ-1 cells treated with 4mmol/L VPA for 72hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dose-dependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dose-dependent manner, the cells were arrested at G0/G1 phase.

结果显示：VPA对MUTZ-1细胞的生长抑制作用呈现时间和剂量依赖性；经4mmol/LVPA处理MUTZ-1细胞72小时后，细胞呈现典型的凋亡形态特征，光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体；透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加，胞装内大小不规则的染色质团块；流式细胞术结果表明，细胞凋亡率随着VPA浓度的增加而逐步增高，G0/G1期细胞比例随着VPA浓度的增加而逐渐增多，S期细胞比例逐渐减低，细胞被阻滞在G0/G1期。

Information is stored in mass storage systems in large units called files. A typical file may consist of a complete text document, a photograph, a program, or a collection of data about the employees in a company. The physical properties of mass storage devices dictate that these files be stored and retrieved in multiple byte units. For example, each sector on a magnetic disk must be manipulated as one continuous string of bits. A block of data conforming to the physical characteristics of a storage device is called a physical record. Thus , a file stored in mass storage will typically consist of many physical records.

在大容量存储系统中，信息是以称为文件的大的单位储存的，一个典型的文件可以是一个全文本的资料，一张照片或一组关于公司员工的数据，大容量存储系统的物理特性表明，这些文件是按照许多字节为单位存储的检索的，例如，磁盘上每个扇区必须作为一个连续的二进制位串进行操作，符合存储系统物理特性的数据块称为物理记录，因此存放在大容量存储系统中的文件通常包含许多物理记录。

China has implemented new courses in a few years, the study of middle school teachers teaching and students studying math on the investigation at this stage Instructional Design Research expounded on the need from classroom teaching and learning theories analysis, to find guidance in the design of classroom teaching under the new curriculum theory and classroom teaching on the design analysis of the whole process; From the typical class (class mathematical concepts and mathematical theory classes and study complicated math classes, the study of mathematics learning courses, open learning mathematics classes, cooperative learning math lessons) teaching the practice of design study, initial design, this is my classroom teaching design in recent years the practice of summary, the results of this study reflect.

新课程在我国已实施好几年了，本研究通过对初中教师与学生数学教学情况的调查，阐述研究现阶段课堂教学设计的必要性；从课堂教学理论、学习理论的分析中，寻找指导新课程下课堂教学设计的理论，并就课堂教学设计的全过程进行剖析；从几种典型课(数学概念课、数学原理课、数学复习课、数学研究性学习课、数学开放探究课、数学合作学习课)的课堂教学设计的实践研究中，提出初步的设计思路，这既是本人近年来课堂教学设计的实践总结，也是本研究的成果体现。

The poetics under the influences of Zhuang Zi's ideas formed one kind of transcendental system, and had made contributions in the problems of language and meanings; the Confucian school was on the contrary, they concerned the real time people lived in, so people's activities and the active history were the subject of poetics, and"poetry expresses the mind"was the most typical reflection of this kind of system of poetics; Plato thought that time derived from the eternal idea, he constructed his system of poetics about the "mnemonics"of the idea on the base of this concept of time; Aristotle said that poetry was the imitation of human activities, his famous theory of"mimesis"was built on the"real"activities of human beings.

庄子观念影响下的诗学，形成了一套超验的隐喻体系，在言和意问题上作出了独到的贡献；以孔子为代表的儒家学派则与此相反，关注的是人生存的现实时间，人的行动及行动的历史成为诗学的主体，"诗言志"是这一诗学体系的最典型体现；柏拉图认为时间来源于永恒的理念，他以此为基础建立了对理念的"回忆"的诗学体系；亚理斯多德认为诗应该是对人的行动的模仿，他的著名的"模仿"理论便建立在人在"实在"中的行动上。

Based on the analyses of braking moment distribution between axles of some typical modern passenger cars, this paper analysed first the forces on car and wheels during braking, then summarized the design of pipeline pressure of brake system, the requirements of ECE13 regulation an braking torque of front and rear wheel brake, and the analyses of braking force distribution between axles.the analysing result of a certain car showed that this method of design is practicable and reasonable.this paper will be he...

在对典型现代轿车制动力矩分配进行考察和分析的基础上，本文从整车和车轮在制动过程中受力分析出发，对制动器管道压力的设计、ECE13法则对前后轮制动器制动力矩的要求、轴间制动力分配的验证和分析等方面进行了较为系统的归纳和总结。通过实例分析表明，本文所述的方法较为实用合理，它为汽车产品设计以及有关部门采用有效的制动力矩分配设计方法、保证良好的汽车制动性能提供了一定的依据和参考。

First, in this essay, the author states the reasonableness and necessity of permitting transfer of mortgaged property, affirms that mortgager will not lose the right of dispose and is entitle to transfer the property freely when the property is under mortgage. And at the same time, the author agrees the theoretical basis of droit de suite and the mortgagee's interests can be protected through the enforcement of the recovery right. Second, the author introduces the legislation of droit de suite in several countries with typical civil law legal system and analyses the particular characteristics of these different registrations. Third, the author points out the defects and malpractice of the legislations in our country after analyzing the legislation which state ambiguously the recovery right of mortgage and restricts the transfer of mortgaged property based on the tracing the development of system in respect of transfer of mortgaged property in Chinese legislation on guarantee. Finally, according to the real situation of our country, the author presents some concrete proposals on perfecting the system of transfer of mortgaged property and droit de suite of mortgage to reach the balance between static safety of property rights and dynamical safety of transactions with the reference to successful expericnees of other countries.

本文首先从理论依据出发，论述允许抵押物转让的合理性与必要性，肯定抵押人在抵押期间不丧失对抵押物的处分权，可以自由转让抵押物，同时认为抵押权追及力的存在具有理论基础，通过赋予抵押权以追及效力即可保障抵押物转让关系中抵押权人的利益；其次，简要介绍几个具有典型意义的大陆法系国家关于抵押权追及力的立法状况，分析各国立法的侧重点；再次，结合我国担保立法关于抵押物转让制度的发展轨迹，对我国立法未明确承认抵押权所固有的追及效力，且限制抵押物转让的规定进行剖析，认为存在一定的疏漏和弊端，具有明显的不合理性；最后，根据我国国情，并借鉴国外立法的成功经验，提出完善我国抵押物转让及抵押权追及制度的具体立法建议，以寻求物权的静态安全与交易活动的动态安全的平衡。

Ihde's philosophy of technology is very typical in contemporary American circles of philosophy of technology. His philosophy is not only closely related to former philosophers of technology such as Heidergger and Mumford, but also integrates analytical philosophy and pragmatism with phenomenology. By using materials of history of technology and anthropology, lhde reinterprets former basic problems in the philosophy of technology and forms his own system of philosophy of technology. Ihde's philosophy represents the new directions of American philosophy of technology, which pay attention to the research of the history of technology, the philosophical foundation of philosophy of technology and technological practices.

伊德的技术哲学思想在当代美国技术哲学中很有代表性，他的思想既与以前的技术哲学家像海德格尔、芒福德等人的思想密切相关，又在现象学的基础上融合了实用主义和分析哲学的成分，并借助于人类学和技术史等学科的材料，重新阐释了以前技术哲学中的一些主要问题，形成了自己的现象学技术哲学的思想体系，代表了当代美国技术哲学的最新趋势，即在研究技术史、技术哲学的哲学基础和技术实践的基础上，从不同的角度重新看待技术本身。

Because of the nondirectional property of ionic bond and the fully delocalized property of pi electrons on carbon layers, translation will not change the electronic structure of carbon layers, resulting in that A-GIC and AE-GIC hare quite good lubrication as well. The electrons come from metals mainly transfer to the delocalized pi orbitals of carbon layers, and the increase of delocalized electrons will make metal graphite intercalation compound more electro-conductive than graphite itself. Because ionic bond between metals and carbon layers is weaker and its lattice energy is much less than that of typical NaCl crystal, so metals could be left from interlayers. The Mulliken populations of C-C in intercalation compounds are smaller than that of graphite, and the HOMO energy level of GIC is higher than that of graphite too. These Lead to that GIC will easier be oxidized.

由于离子键没有方向性，又由于碳层中的π电子是充分离域的，所以碳层不会由于平移而改变其电子结构，金属石墨层间化合物仍具有很好的润滑性；金属失去的电子主要转移到碳层的离域π轨道中，碳层离域电子增多使金属石墨层间化合物的导电性比石墨增强；金属与碳层间的离子键强度比较弱，其晶格能远小于典型的离子晶体，因而金属易从石墨层中脱出；金属石墨层间化合物中的C-C间Mulliken布居值小于石墨中C-C间的值，且金属石墨层间化合物的HOMO能级也高于石墨的HOMO能级，所以石墨层间化合物中的碳原子较石墨更易被氧化。

In order to ensure the reasonable modeling method for thermodynamics model, by adopting these four kinds of models and the reference model, the typical thermodynamics characteristic in drum-the dynamic process of"false level"were dynamically simulated, the results of simulation indicate: The modeling method of considering the changing rates of pressure and volume simultaneously is more reasonable, it's simulation result can be consistent with the result of the reference model, and the numeric error is within±5%, so, this method can be used to build thermodynamics model of drum level.

为确定合适的热力学模型建模方法，采用这四种模型和参考模型，对汽包中典型的热力学性质-"虚假水位"现象的动态过程进行了动态仿真，结果表明：同时考虑汽包体积变化率和压力变化率的建模方法，其动态仿真结果完全可以正确地跟踪参考模型的仿真结果，并且数值误差在5%以内，故该建模方法可以用来建立汽包水位热力学模型。

This paper determines the design idea of combining VISC with structural optimization design. Problems which existed in structural optimization design are analyzed and contents of optimization process are determined. Calling and dominating calculation program written in FORTRAN in the development environment of Delphi are realized by the techniques of FORTRAN/Delphi mixed-language programming and multi-threaded application. Parallel coordinates visualization technology is deeply researched and applied in software exploitation of optimization process. Essential programs of VISC software are compiled. Approaches which can improve efficiency of optimization are discussed. In the end, functional modules are integrated and a typical computational example is verified.

本文通过对结构优化设计和科学可视化的研究，确立了天线结构优化设计与科学计算可视化技术紧密结合的思路；根据天线结构优化设计的特点，针对优化设计中存在的问题，对系统结构优化的总体框架进行了分析和论述，确定了优化过程可视化的具体内容；通过FORTRAN与Delphi的混合语言编程实现了在Delphi环境下对FORTRAN计算程序的调控，充分利用了原有FORTRAN程序资源；对平行坐标技术进行深入研究，并将其应用于优化过程可视化模块的软件开发中，实现多维数据空间的可视化；编写优化计算过程可视化软件的核心程序；探讨了提高优化效率的途径；对基于可视化的天线结构优化设计软件系统进行集成，针对某天线进行了算例验证。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐