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Conclusions/interpretation These findings indicate the presence of a subclinical enteropathy associated with type 1 diabetes that is already detectable before clinical onset of the disease, and suggest that the small intestine is an organ participating in the pathogenetic process of type 1 diabetes.

结论/解释:这些结果表明1型糖尿病在临床发病前即可检测出亚临床肠道病变的存在,同时提示小肠参与1型糖尿病的发病过程。

Objective To observe and analyze the expression of fasciculation and elongation protein zeta-1 (FEZ1) gene in purified type-1 astrocytes (T1A) and type-2 astrocytes (T2A).

目的 探讨轴突成束和延伸蛋白ζ-1(FEZ1)基因在1型和2型星形胶质细胞(T1A、T2A)中的表达差异,及其在新生SD大鼠中枢神经系统中的表达。

In three separate studies, the investigators evaluated 105 adults with type 1 diabetes (mean age, 37 years; mean duration of diabetes, 20 years), 36 adults with type 2 diabetes (mean age, 50 years; mean duration of diabetes, 10 years), and 91 adults with type 1 diabetes (mean age, 39 years; mean duration of diabetes, 20 years). During a four-week period, participants used a hand-held computer to complete 70 trials of cognitive-motor tasks and to enter their current blood glucose reading after each test. Hyperglycemia was defined as blood glucose level higher than 15 mmol/L.

在3个不同的试验中,研究人员评估105位第1型糖尿病患者(平均年龄为37岁;患糖尿病平均时间为20年),36位第2型糖尿病患者(平均年龄为50岁;患糖尿病平均时间为10年),以及91位第1型糖尿病患者(平均年龄为39岁;患糖尿病平均时间为20岁);在4周期间,受试者使用一种掌上型电脑来完成70种认知运动任务的试验,以及在每次测试后,输入他们目前的血糖读数,血糖高於15 mmolL被定义为高血糖。

Through binding GLP-1 receptor , it can arouse insulin secretion, increase sensitivity of insulin, restrain glucagon secretion and slower the velocity of stomachic emptying. More recent studies showed that GLP-1 is effective for both type 1 and type 2 diabetes mellitus. Treatment of type 2 diabetes patients with GLP-1 does not lead to hypoglycemia.

此外,GLP-1通过激发其受体产生生理功能,能明显刺激胰岛素分泌、增加胰岛素敏感性、抑制胰升血糖素水平和减慢胃的排空,对2型糖尿病和1型糖尿病均有效,而且将其用于治疗不会产生低血糖。

Results (1)Relevance rate of behavioral problems in type 1 diabetes group was 20.2%,two fold significantly higher than that in the control group(8.2%)(P=0.000).(2)Logistic analysis showed that risk factors concerned behavioral problems in diabetic children and adolescents included patients lived in rural areas,poor parents' marital relationship,poor parent- child relation,improper cultural ways,poor communication and understandings between family members,uniparental family and poor control of blood glucose.(3)It was found that diabetes was the most significant risk factor affected the occurrence of behavioral problems among all related factors based on the analytic results in both the type 1 diabetes group and the health group.Conclusions (1)Children and adolescents with type 1 diabetes are the high- risk population who are apt to the occurrence of behavioral problems.

结果①行为问题的检出率:糖尿病患儿检出率为20.0%,与健康对照组(8.2%)比较,糖尿病患儿行为问题检出率高于健康对照组P=0.000;②Logistic回归分析显示,与糖尿病患儿行为问题有关的危险因素分别为在农村生活、双亲关系紧张、亲子关系差、缺乏直接感情交流、教育方式不当、对子女了解较少、仅由父母中的一方承担管理子女的责任及血糖控制不良;③将健康对照组与1型糖尿病组综合分析后发现:影响行为问题发生的所有危险因素中,患糖尿病的相对危险度最大。

Results Of 4 cases breast MALT-ML, 2 were CCL type, 1 CCL type with blastoid transformation, monotoid Bcell type. By immunohistochemistry, all cases were monoclonity of B-cell with follicular colonization and lymphoepithelia lesions.

结果:4例乳腺MALT-ML中2例为CCL细胞型,1例为CCL细胞型向母细胞样转化,另1例为单核样B细胞型。4例均显示B细胞单克隆性及滤泡克隆化和淋巴上皮病变。

The researchers used the Lesch typology to classify patients into four types of alcohol dependence: type 1, those who suffer from heay alcohol withdrawal and use alcohol to weaken the withdrawal symptoms; type 2, indicating those who use alcohol for its anxiolytic effects; type 3 ("depression"), coering patients who hae an underlying affectie disorder that accounts for the alcohol abuse; and type 4 ("adaptation"), applied to those who hae premorbid cerebral defects, behaioral disorders, and a high social burden.

研究者使用lesch类型学把病人分为四种酒精依赖型:1型,那些遭受沉重酒精戒断症状并使用酒精减轻戒断症状的人;2型,表示那些依赖酒精的镇静效果的人;3型,涵盖有可导致酗酒行为的潜在情感障碍的病人;而第4型,适用于那些有病前脑缺陷、行为失常或有很高社会负担的人。

First, the use of notes 1-1 products for the short form of wedge-type engine connecting circular cone chuck ; 1-2 cards similar form of Shuchi Type ; 1-3 chuck installation : 1-3-1 will be the most fuel piston onto the end 1-3-2 unloaded chuck Fangchenge will chuck fixed transition to the main site, and then push and pull with the adjustment nut to wedge tube wrenches hearts sets top face below the front face plate intimate 1mm; 1-3-3 loaded Fangchenge; 1-4 regular monthly use of the process should be clear brush to avoid internal malfunction.

请各位大虾帮小弟翻译一下使用说明书不胜感激!一、使用说明 1-1 本产品为短圆锥连接形式的楔式动力卡盘;1-2卡爪形式为梳齿式;1-3 卡盘的安装: 1-3-1 将油缸活塞推到最前端 1-3-2 卸下卡盘防尘盖,将卡盘固定到主轴过渡盘上,然后用筒子扳手调整推拉螺母使楔心套顶面低于盘体内腔前端面1mm; 1-3-3 装上防尘盖; 1-4 使用过程中应每月定期清刷,以免内部发生故障。

The experimental results showed that the self-thinning power of abil-1 (-1.49) was smaller than that of wild type (-1.35), and the self-thinning power of eral-2 (-1.21) was greater than that of wild type.

结果显示,abil-1的自疏指数小於野生型且eral-2的自疏指数大於野生型。

Ten alleles sequenced had the same modular structure, starting with a repeat block of Type 3 followed by a block of Type 1 before the central block of Type 3 (313) at 5'end, and starting with a repeat block of Type 4 followed by the central repeat block of Type 3 (43) at 3'end.

另一种为新发现的变异核心序列,暂命名为7型(type 7)。10个等位基因具有相同的模块结构,在5'端表现为:3型一1型--3型(313)排列,在3'端则表现为:4型一3型(43)排列。

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