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He gradually formed the Gelug Sect of Tibetan Buddhism.He wears a yellow ogival hat, with two lotus flowers growing out of his two hands on his two shoulders. Inside the right lots flower there are Buddhist Scriptures and inside the left lotus flower there is a sword. It is said that Tsong Kha-pa was the incarnation of Manjusri.

藏传佛教格鲁派创始人，他头戴黄色的尖顶帽，双手作结法轮印，从双手生有两茎莲花，花开在左右肩膀上，右边莲花中有一包经卷，左边莲花中有一把宝剑，这是宗喀巴像在明显标志，和文殊菩萨的表示一样，据说宗喀巴十文殊菩萨转生来的。

Objective To establish rat model with polycystic ovary with two different methods:testosterone plus human chorionic gonadotropin and progestogen plus HCG,compare the rat models induced by testosterone plus HCG with the patients with polycystic ovary syndrome in the aspects of ovarial morphous and gonadal hormone,and investigate whether testosterone with HCG is the effective method to establish rat model with polycystic ovary syndrome,than compare two methods(T+HCG and P+HCG)finally to draw a conclusion if there are any difference or similary between the two methods and which one is more ideal and convenient.Methods 60 SD female rats of 23 days were divided into three groups in random.

目的 本实验用睾酮联合绒毛膜促性腺激素及炔诺孕酮联合HCG两种方法分别建立多囊卵巢大鼠模型，将模型鼠的卵巢形态及血清激素方面改变与人类多囊卵巢综合征的病理改变加以比较，探讨睾酮联合HCG是否是建立多囊卵巢大鼠模型的有效方法，并比较两种造模法是否存在异同点，判断哪一种造模方法更为理想及简便有效。

Bama Mini-pig cloned embryos of 0.5-1.5 days old were surgically transferred to the oviductal ampulla of two female Bama Mini-pigs and two female Guangxi Luchuan pigs, of which the two female mini-pigs and one Luchuan pig returned to estrus, and one female Luchuan pig gave birth of one male cloned Bama mini-piglet.

利用刺入式手术胚胎移植法，将0.5~1.5日龄巴马小型猪克隆胚移植到2头巴马小型猪和2头陆川猪的输卵管壶腹部。其中2头巴马小型猪和1头陆川猪返情，另外一头陆川猪于2007年10月13日产下1头克隆雄性巴马小型猪。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

In this thesis, PESA was synthesized using two different methods: the conventional one-step method and the two-step method we have developed. The corresponding products obtained by the one-step method and the two-step method are named PESA I and PESA II, respectively.

本文采用传统的一步法和非传统的两步法合成了PESA Ⅰ和PESA Ⅱ两种不同的产物，并通过单因素和正交试验确立了最佳合成路线。

The famciclovir was synthesized from purine by a series of steps by Acylation, Decarboxylation, Reduction ,and so on; Derivatives of these intermediates is described from the 6-chloro- 9H- purin-2-amine as raw materials in different conditions when the iodine and bromide were synthesized with the addition of two intermediate 6-bromo-9H-purin-2-amine and 6-iodo-9H-purin-2-amine; There is elaborated from the main part of a acetophenone, urineaminohydrochloride, phenylhydrazine, ethyl acetoacetate as raw material through a series of reactions to synthetic 3-phenyl-4-formylphenyl pyrazole and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-aldehyde two pyrazole aldehyde, and then with 2-amino-6-chlorine-9-(2-methicillin-oxo-co-methyl-4-yl) purine reaction of the two new pyrazole purine Schiff bases.

本论文主是采用以鸟嘌呤为原料，经过一系列的酰基化，脱羧，还原等反应作用下最终得到了产物2-氨基-9-(4-乙酰氧基-3-乙酰氧基甲基丁基)嘌呤；其中的中间体衍生物主要是阐述从以2-氨基-6-氯鸟嘌呤为原料通过在不同的条件下进行溴代与碘代分别合成了另外两种中间体2-氨基-6-溴鸟嘌呤及2-氨基-6-碘鸟嘌呤；还有一部分主要是阐述从以苯乙酮，盐酸氨基脲，苯肼，乙酰乙酸乙酯为原料通过一系列的反应先合成3-苯基-4-醛基吡唑及5-氯-3-甲基-1-苯基-1H-吡唑-4-甲醛这两个吡唑醛，然后再与2-氨基-6-氯-9-(2-甲氧羰基丁酸甲酯-4-基)嘌呤反应得到了两个新型的吡唑嘌呤席夫碱

Using ca pillary rube model of porous media,scaling coefficients of capillary pressure ar e deduced in this paper. The results show that the scaling coefficients, in the same porous medium, if any pair of two-phase (usually air-water two phase syst em is selected as the reference) capillary-saturation relationship is known, then the other two-phase (air-NAPL and NAPL-water) capillary-saturation relations hips can be obtained too.

从而得出对于同一介质中的任意两相流动，只要某两相的毛细压力饱和度关系已知，其它任意两相的关系都可以通过所得出的毛细压力折算系数而得到。

Water margin,that a work dedicated to masculine has always been highly appreciated.yet,it is beyond any doubt that the book presents a biased and even unjust feature of the feminine .there are few women personages in water margin which can be divided into two kinds briefly: namely "lady of easy virtue" and "heroine".novel go on two extremes overly that women'figure was denied impersonal role maid image mould either "bad" or reach "manlike " so that they cant cross to two description of woman these because the writer was intended or involuntary to describe them these.consequently the women' figure maked untrue exceedingly as to the lady of easy virtue write it to the limit excessively ruthlessly poisonously ; as for heroine write its walk chivalrous and loyal to the limit that the woman wasn't defeated by men.the female extreme image was pointed out that the intention of author come from the influence of the super male consciousness to a certain extent and it is inevitability because of masculine being in charge of linguistical power ,in fact, the appearance of women was just only minor role in order that the hero world need to regard man as the centre too.in a word womens destiny in water margin is a miserable foregone!

水浒传》是1部以描写男性英雄为主的名著，历来受到较高评价。然而，作品在女性形象塑造时存在的偏颇甚至不公正却是毋庸置疑的。《水浒传》中的女性人物屈指可数，主要可分为两大类：1是所谓的荡妇恶婆；2是所谓女英雄。作家在对这两类型女性的描写时，都因作者有意或无意的女性意识而走向极端化，实际上是走上了两个无法交汇的极端，使女性形象的塑造过于偏激，不是&淫恶&到极端，就是&男性化&到极点，写淫妇恶婆，写尽其淫，狠，毒；写女英雄，则写尽其行侠仗义，巾帼不让须眉。这种极端化的女性角色定位，既是作者男权意识的自然反映，又是男权社会男性话语权的必然呈现，说白了，出现在《水浒传》的女性不过是点缀和突出男性的生活，是为表现父权制男性英雄世界服务的。

The two-dimensional structural units (such as silicon-oxygen tetrahedral sheet, octahedral sheet), interlayer space are assembled according to the sphere close packing manner, and the close packing layers parallel to {0001}. There are several mechanisms to release the difference in size while the silicon-oxygen tetrahedral sheet and octahedral sheet assemble the TO and TOT-type structural layers. The two types of structural layers with different interlayer space fitted together in six kinds of assembling modes and formed six kinds of crystal layers. The combinatorics analysis of the two-dimensional structural units revealed that there may be 28 kinds of TOT type interstradified minerals in six kinds of polysomatic assembling modes of interatradified structure. The structural layer is symmetrical for octahedron sheet in the structure of interstratified minerals and shows polarity characteristics.

结果表明，不同二维结构单元体（包括硅氧四面体片、八面体片、层间域的构筑基本符合球体紧密堆积原理，紧密堆积层平行{0001}；四面体片与八面体片构筑TO和TOT结构层时采取多种机制消除二者在二维尺寸上的差异；两种模式的结构层与不同类型的层间物组装形成六种组装模式的晶层；并通过二维结构单元体的组合规律的分析，计算出可能存在的28种TOT型间层结构，它们分属于6种间层结构多体性组装模式；间层结构中，结构层对于八面体片是不对称的，并在属性上表现出极性特征；间层矿物的晶层类型可用6种多体性组装模式加以表达。

Through Hilbert transform, a signal's plane trace can be get. There are two frequencies in the tested signal, so the signal's plane trace may be looked as the track of the out pole's end when two poles rotate around parallel axles. Using the knowledge of motion synthesis in theory mechanics, a formula to describing the change of plane trace's step length and angle for two-frequency be get. So we may prolongate the tested signal's plane trace from the echo's initial arriving moment, and get a certain length of the signal's prolongation.

通过Hilbert变换可得到测试信号的平面迹线，测试信号中只含有两个频率成分，视为双频信号，双频信号的平面迹线相当于两连杆绕平行轴转动时外杆杆端迹线，利用理论力学中运动合成和瞬心知识，推导出双频信号平面迹线步长平方满足余弦线性复合函数，而迹线转角可视为线性变化，据此可对回波到来之前的测试信号平面迹线作延长，得到一定长度的信号延展段，信号延展段与实测段作差可得到一次、二次回波的第一个波峰值。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新