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Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果：倒置显微镜和透射电镜观察显示，经SAHA处理的细胞增殖速度显著减慢，细胞体积增大，细胞核较小，形状较为规则，核仁数量减少、体积变小，核内常染色质增多而异染色质减少，核质比例减小，细胞质内线粒体数量增多、线粒体嵴发达，高尔基体较为典型，粗糙型内质网增多，呈现出与正常上皮细胞相似的形态变化；MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用，并有明显的剂量依赖和时间依赖关系；免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达；流式细胞仪检测结果显示，SMMC-7721细胞经SAHA处理后，G0/G1期细胞明显增加，S期细胞则明显减少，细胞被阻滞于G0/G1期；RT-PCR检测结果表明，SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加，24h后更为明显。

Method］twenty six wistar rats were divided into two groups, with 13 in each group, peroneal nerve was transacted on the right side of all the animals, in one group, the proximal end of peroneal nerve was turned back and ligated, the distal end was sutured to the side of tibial nerve with perineurial window, in another group,both ends of the transacted peroneal nerve were turned back and ligated as contrast, no operation was done on the left side.

方法］wistar大白鼠26只，随机分实验组和对照组，每组13只，实验组右侧腓总神经切断后，近端反转结扎，远端与胫神经外膜开窗处行端侧吻合，对照组右侧腓总神经切断后，两端均反转结扎，两组动物左侧作正常对照，不作处理。术后3个月，行双侧腓总神经、胫前肌组织学检查，胫前肌湿重测定，运动终板检查。

The game appeared to have early momentum in the Yankees' direction, as Johnny Damon slugged a disputed home run to open the game and saw a reversed call work in his favor, but any luck quickly turned as Wang, the Yankees' Game 1 starter in two consecutive playoff series, turned in one of his worst outings of the season.

其实今天洋基一开始就打出气势。大门一开始首打席就击出阳春炮为洋基取得领先优势。但运势在王建民手上马上被逆转。洋基的先发投手王建民连续两年在季后赛首战先发，但他今天是他今年表现最差的一场比赛之ㄧ。

If it could, for all that is built into the concept, have turned out that "water" referred to any waterish stuff, or that it could have turned out that "water" had indeterminate reference, then this is enough to show that we should not regard it as a piece of conceptual analysis that water is the actual waterish stuff around here.

如果是这样，对所有进入到概念中的东西，证明&水&指称任何水性材料，或可以证明&水&有不确定指称，那么，这足以指出，在这里我们不应该取为对&水是这里的现实的这些水性材料&的概念分析。

By means of simulink of Matlab, it is known that the method that electric field is strengthened and two damp holes are turned on can lead to transfer ratio of force to be fallen during the phase of low frequency; on the other hand, the method that electric field is weakened and two damp holes are turned off can lead to transfer ratio of force to be fallen during the phase of high frequency.

通过Matlab仿真计算可知，振动物体在低频阶段，加大电场和开启两阻尼孔能使力传递率较低；而在高频时，关闭电场和阻尼孔，其力传递率较小。

objective to evaluate efficacy of extracorporeal shock wave lithotripsyfor treating ureteral stones in situ,investigate the cause of higher re-treatment rate.methods total of 687 patients with ureteral stone were received eswl between january 2000 and december 2004,included 455 male(66.2%) and 232 female(33.8%) patients,6 cases have bilateral ureteral calculi,12 cases have unilateral multiple calculi.hence,together 709 ureteral calculi were treated.patients upper ureteral calculi were treated in the supine position,for lower ureteral calculi patients were turned prone.to reduce eswl-induced renal trauma and pain,using lower energy source,adjusted power setting from 9.8 to 13.2kv,limited 1500 shock wavs per one session.no auxiliary procedure were used before eswl.the stone size was measured as the surface area of stone length by stone width on x-ray film.the interval between two treatment sessions was two weeks.results of 709 ureteral calculi,the overall stone free rate was 97.3%(690 calculi),re-treatment rate was 34.1%(292 calculi).according to the performed treatment sessions,one session 467 calculi,the mean stone size 37.27mm2,stone free rate 65.4%(464 calculi).two sessions 138 calculi,the mean stone size 62.48mm2,stone free rate 18.4%(131calculi).three sessions 52 calculi,the mean stone size 79.60mm2,stone free rate 7.1%(50calculi).four sessions 19 calculi,the mean stone size 101.63mm2,stone free rate 2.4%(17calculi).fivesessions 33 calculi,the mean stone size 119.33mm2,stone free rate 3.9%(28 calculi).overall 19 cases(2.7%)turned to other treatment modalities.of 335 upper ureteral calculi,303 achieved stone free (95.8%),re-treatment rate was 38.5%(129 calculi).of 374 lower ureteral calculi,369 achieved stone free(98.7%),re-treatment rate was 30.2%(113 calculi).the re-treatment rate of upper ureteral calculi was higher than lower ureteral calculi(p＜0.05,χ2=5.40).the difference of stone-free rate between upper and lower ureteral calculi was no significant(p＞0.05,χ2=0.15).conclusion eswl should be considered first line therapy for ureteral stone still.stone burden are the main variable of higher re-treatment rate,upper ureteral stone may moving with respiring during eswl.so efficinet shock wave was decreared,re-treatment rate become higher.

目的 评估体外震波碎石治疗输尿管结石的疗效，探讨再治疗率高的原因及输尿管结石的治疗选择。方法回顾2000年1月～2004年12月间eswl治疗输尿管结石的临床资料687例，男455例（66.2%），女232例（33.8%），平均年龄46.6岁（15～83岁）。有双侧输尿管结石6例，单侧多发性输尿管结石12例（4颗1例，3颗2例，2颗9例），共计输尿管结石709颗（含透光结石13颗）。应用上海爱申公司生产的desunit6030型碎石机，c臂x线球管做结石定位。上段输尿管结石（肾盂输尿管交界处至骶髂关节上缘）取仰卧位，下段输尿管结石（骶髂关节上缘下至输尿管口）取俯卧位。为减少eswl引起的肾损伤和疼痛，应用较低的能量，震波发生器电压从9.8～13.2kv，震波频率1.5s。每次治疗设定为1500次震波。治疗后3天摄腹部平片或b超，以后每隔7日重复检查。假如结石未碎或有残留结石最长径＞3mm以上，再次eswl，两次治疗的间隔时间为两周。结石的大小用x线片上的表面积（mm2表示。结果 709颗输尿管结石总的治愈率为97.3%（690颗），再治疗率34.1%（242颗）。其中一次治疗467颗，平均结石大小37.27mm2，治愈464颗（65.4%），3颗改治疗；两次治疗138颗，平均结石大小62.48mm2，治愈131颗（18.5%），7颗改治疗；第1和第2次治疗治愈率（1个月治愈率）为83.8%。3次治疗52颗，平均结石大小79.60mm2，治愈50颗（7.1%），2颗改治疗；4次治疗19颗，平均结石大小101.63mm2，治愈17颗（2.4%），2颗改治疗；5次及5次以上治疗33颗，平均结石大小119.33mm2，治愈28颗（3.9%），5颗改治疗。总计19颗（2.7%）结石改变治疗方式。上段输尿管结石335颗，治愈321颗（95.8%），再治疗129颗（38.5%）。下段输尿管结石374颗，治愈369颗（98.7%），再治疗113颗（30.2%）。经χ2检验，上、下段输尿管结石的再治疗率差异有显著性（χ2=5.40，p＜0.05），治愈率差异无显著性（χ2=0.15，p＞0.05）。不良反应：血压升高13例（1.9%），震波区域疼痛26例（3.8%），震波进入处皮肤点状淤血33例（4.8%），肉眼血尿128例（18.6%），均于第2、3天自行消失。结论 eswl目前仍是输尿管结石的第一线治疗，结石的大小是再治疗率高的主要因素。结石的位置有影响，上段输尿管结石可随呼吸移动，有效震波次数减少，再治疗率比下段输尿管结石高。eswl前注重病例筛选可降低再治疗率。

Whenever the NAI generator was turned on or turned off, the coefficient of concentration decay of 30 nm particulate is larger than 300 nm particulate ; the ECR of 30 nm particulate is also larger than 300 nm particulate. With regard to different species particulate, when the NAI

在不同粒径微粒方面，不论是关闭或是开启空气负离子，30 nm 微粒之浓度衰减系数比300 nm 大；30 nm 微粒之有效清净速率(effectivecleaning rate， ECR )亦比300 nm 微粒大。

Whiter Shade of Pale 歌词: We skipped the light Fandango And turned cartwheels across the floor I was feeling kind of seasick But the crowd called out for more The room was humming harder As the ceiling flew away When we called out for another drink The waiter brought a tray And so it was that later As the miller told his tale That her face at first just ghostly Turned a whiter shade of pale She said There is no reason...

A Whiter Shade of Pale 苍白的浅影※全球版加收、音乐录影带拍摄中曲词：盖瑞布鲁克＆凯斯瑞德这首1967年横扫全球流行乐坛（在英美的各流行榜都荣获冠军）的抒情摇滚经典，至今已有为数相当的翻唱版本，原唱团体有个怪异的名字：Procul Harum（引自古罗马的诗作，大意为&这些事物之外&）。

Back of flat-bed rickshaw +则+ avoid too late + directly/immediately + hit and turned over by the Toyota, the young man driving the rickshaw was hit after the electric pole on the roadside + hit and turned over + on the ground.

刘先生说，紧随摩的后的平板三轮则躲闪不及直接被丰田撞翻，骑三轮的小伙子正好撞在路旁的电线杆上后翻倒在地。

In our most trivial walks, we are constantly,though unconsciously, steering like pilots by certain well-known beacons and headlands, and if we go beyond our usual course we still carry in our minds the bearing of some neighboring cape; and not till we are completely lost, or turned round —— for a man needs only to be turned round once with his eyes shut in this world to be lost—— do we appreciate the vastness and strangeness of nature.

在我们的日常散步中，我们经常地，虽然是不知不觉地，像领港的人一样，依据着某某灯塔，或依据某某海角，向前行进，如果我们不在走惯的航线上，我们依然在脑中有着邻近的一些海角的印象；除非我们完全迷了路，或者转了一次身，在森林中你只要闭上眼睛，转一次身，你就迷路了，——到那时候，我们才发现了大自然的浩瀚与奇异。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失