查询词典 tunica intima

The aortic tunica intima was intact, the number of foam cells was decreased, and inflammatory cells infiltrated into the med-intima smooth muscle of the n-3 PUFA group. However, with no such changes were observed in control and n-3 PUFAs groups. Little or no expression of NF-κB, ICAM-1 and MCP-1, and a high expression level of IκBα were detected in aortic tunica intima of the n-3 PUFA and control groups, while high expression levels of NF-κB, ICAM-1 and MCP-1, and little expression of IκBα were detected in aortic tunica intima of the high fat-fed group.

结果 n-3脂肪酸组大鼠体重第1~11周均明显降低，空腹血糖、血清胰岛素、TG、TC、LDL-C、总FFA和内脏脂肪占体重百分比均明显低于HF组，HDL-C则明显高于HF组，与对照组无明显差别；n-3脂肪酸组大鼠主动脉主动脉内膜完整无内皮细胞脱落现象，内膜下泡沫细胞及炎细胞浸润减少，内膜的NF-κB呈弱阳性表达，IκBα呈阳性表达，ICAM-1和MCP-1均呈阴性或弱阳性表达。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

Hybridization of cDNA probe and gene chip was carried out, gene chip was scanned with Scan Array3000, and results were analyzed with ImaGene 3. 0. Result: 1 Toluidine blue staining of semithin section showed: compared with control group, the boundary of tunica intima, tunica media and tunica adventitia was not distinct, tunica intima and internal elastic membrane was thickened and multilaminar.

将标记了荧光素的cDNA与细胞周期相关基因表达谱芯片杂交，扫描并分析杂交结果。cy5/cy3 ratio值在0.5～2.O之外且一对Double基因表达趋势一致的基因为表达有差异基因，ratio值＞2.O表明DM组该基因上调，ratio值＜0.5表明DM组该基因下调。

Results①The tunica intima and tunica media of the BVs were thin, the tunica adventitia was thick. No complete layer of smooth muscle was found in the tunica intima, the SMC with single elliptical or rod-shape nuclear, fusiform in shape and different in length, ran longitudinally and distributed unequally in the wall of BVs, intercrossed with each other, endothenial cell wasn't covered fully sometimes.

中膜未见完整平滑肌层，SMC呈梭形，大多呈纵切面，有的呈斜切面，不均匀地分布于管壁中；平滑肌纤维长短不一，相互交错排列，有时并不完全覆盖内皮细胞，细胞核单个，椭圆形或长杆状。

Pulmonary vein walls of dogs were composed of 3 layers: the tunica intima, tunica media and tunica adventitia.

P样细胞可能是引发房颤的异位兴奋的形态基础。

Results The body weight, visceral fat and body weight ration, as well as the levels of blood glucose, insulin, triglyceride, total cholesterol, LDL, and total FFA, were significantly lower in high fat-fed group than in control group (P.01). The aortic tunica intima was intact, the number of foam cells was decreased, and inflammatory cells infiltrated into the med-intima smooth muscle of the n-3 PUFA group. However, with no such changes were observed in control and n-3 PUFAs groups.

结果 n-3脂肪酸组大鼠体重第1~11周均明显降低，空腹血糖、血清胰岛素、TG、TC、LDL-C、总FFA和内脏脂肪占体重百分比均明显低于HF组，HDL-C则明显高于HF组，与对照组无明显差别；n-3脂肪酸组大鼠主动脉主动脉内膜完整无内皮细胞脱落现象，内膜下泡沫细胞及炎细胞浸润减少，内膜的NF-κB呈弱阳性表达，IκBα呈阳性表达，ICAM-1和MCP-1均呈阴性或弱阳性表达。

SIS was obtained by firstly removing the tunica mucosa, serosa and tunica muscularis through mechanical erasion.

首先通过机械刮除方法去除粘膜层、肌层和浆膜层，初步得到SIS。

RESULTS:6 of 148 cases were found testis tumor of seminoma;2 testis cyst ; 5 testis inflammation ; 5 testis traumaincluding 3 laceration of testis,2 testis hematoma ; 4 testis torsion ;25 epididymal masses (including 19 epididymal cyst,5 epididymal inflammatory nodules and 1 epididymal tuberculosis ;44 cases were hydrocele of tunica vaginalis( including 31 hydrocele of testis tunica vaginalis,13 funicular hydrocele); 26 cases were cryptorchidism ; 31 cases were varicocele.

结果：148例中阴囊、睾丸附睾疾病包括：睾丸肿瘤6例；睾丸囊肿2例；睾丸炎5例；睾丸损伤5例（睾丸裂伤3例、睾丸血肿2例）；睾丸扭转4例；附睾肿块25例（附睾囊肿19例、附睾炎5例、附睾结核1例）；鞘膜积液44例（睾丸鞘膜积液31例、精索鞘膜积液13例）；隐睾26例；精索静脉曲张31例。

The expression of PDGF receptor α was rather weak, expression in tunica was 2～3 fold higher than in tunica media at 2 w.

PDGFRα表达较弱，2周时内膜表达是中膜的2～3倍，术后2小时～2周表达强度无明显变化，实验组与对照组无差异。

There was no expression of CTGF protein in the pulmonary arteriole of the normal group, whereas, it was highly expressed in the tunica adventitia, slightly expressed in the endangium and rarely expressed in the tunica media of pulmonary arteriole in the hypoxemic group.

正常对照组大鼠肺小动脉壁CTGF蛋白未表达；低氧组大鼠肺小动脉壁外膜CTGF明显表达，内膜略有表达，中膜几乎无表达。

The witness also told the jury at the Royal Courts of Justice in London that he saw a paparazzo fighting with a member of the public who was trying to stop him taking pictures in the minutes before the emergency services arrived.

他还告诉在伦敦皇家法庭的陪审团，在急救服务到来之前，他当时看见一个狗仔队正和一群阻止他拍照的人打架。

The entire N／C program on a tape is made up of an accumulation of these successive data blocks.

纸带上的整个数控程序由这些连续数据单元连接而成。