查询词典 translocates

It is postulated that IP induces the release of endogenous protective molecules that interact with cognate receptors to activate PLC through mediation of the chincough virus sensitive proteins. PLC hydrolyzes membrane phospholipid and produces diacylglyccerol,that,by working together with calcium hydronium,translocates PKC from cytoplasm to cell membrane and activates PKC.

推测缺血预处理细胞保护作用机制是：缺血预处理引起内源性保护物质释放，作用于细胞膜上的相应受体，通过百日咳病毒敏感性G蛋白的介导而激活磷脂酶，磷脂酶水解膜磷脂，产生二酰基甘油(diacylglyccerol，DAG)，DAG和Ca2+协同作用于PKC，使其从胞浆转位到细胞膜并且被活化，PKC在膜上使底物蛋白磷酸化，引发一系列相关信号转导通路的激活，调控保护性基因的表达，从而提高细胞对缺血再灌注损伤的耐受性。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase II detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白-1 (Kelch-like ECH-associated protein-1， Keap1)可将Nrf2与肌动蛋白细胞骨架一起收集在细胞质内，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1脱离，进入细胞核并与ARE结合，从而激活多种抗氧化基因和II相解毒基因的转录。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase Ⅱ detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白－1(Kelch-like ECH-associated protein-1， Keap1)与Nrf2耦联，并与肌动蛋白细胞骨架结合被锚定于胞浆，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1解耦联，进入细胞核并与ARE结合，从而激活多种抗氧化基因和Ⅱ相解毒酶基因的转录。

At last activated ERK translocates into the nuclear and initiates gene transcription.

过量或者不适当的FGF信号会导致某些癌症的发生以及发育过程的紊乱。

There may be other proteins acting like GLUT4, that is, translocates in and out of lipid microdomains in response to stimulation.

它代表了一类与脂质筏和质膜微囊相关的，受胰岛素影响定位发生改变的蛋白质。

After phosphorylation by CG, ERK1/2 translocates to the nucleus in a time-dependent manner.

由CG磷酸化后，ERK1/2以时间依赖性方式向细胞核转移。

NuSAP is localized in the nucleus in interphase, and translocates to the spindle during mitosis phase.

这表明NuSAP是一种重要的微管调控分子，因而可能参与有丝分裂期调控。

The subunit translocates to the nucleus, where it activates transcription.

胞外结构的二聚体化引起跨膜结构域在膜内进行横向扩散，并启动与胞质结构域的接触。

It is known that AICD interacts with some proteins, and AICD translocates into the nucleus and binds with some transcription factors. But the function of AICD is still not clear.

目前发现AICD会与一些蛋白质产生交互作用，且发现AICD会进入细胞核中，与一些转录因子结合，但目前对於AICD之生理功能仍不清楚。

Despite recent progress in the study of Bax during apoptosis , it remains unclear how Bax translocates to mitochondria and then induces the release of cytochrome c and other substances.

虽然关于Bax蛋白的研究已经取得了很大进展，但是Bax蛋白是如何转位到线粒体以及如何引起细胞色C释放等许多问题尚未十分清楚。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。