查询词典 transcriptional

Based on these data, we proposed a hypothetical model for the involvement of reversible histone acetylation in transcriptional regulation of the p16INK4a gene.

基于这些实验结果，我们推测出可逆的组蛋白乙酰化参与p16INK4a基因的转录调控的模型。

Experiments show that Ang Ⅱ activates JNK mediated by AT〓, and JNK increases transcription activity of c-Jun by phosphorylating c-Jun amido-terminal, and induces expression of c-Fos gene. c-Jun and c-Fos form transcriptional factor activated protein-1 complex. AP-1 may stimulates genes which correlate with cardiovascular remodeling expression, such as transforming growth factor, collagen type Ⅰ and Ⅲ, skeletal muscle α-actin,β-MHC, atrial natriuretic factor.

实验表明，在心肌和血管平滑肌细胞Ang Ⅱ通过AT〓介导激活JNK；JNK通过磷酸化c-Jun氨基末端增加c-Jun的转录活性并诱导c-Fos基因表达，c-Jun和c-Fos蛋白形成转录因子复合物激活蛋白-1(AP-1)，并刺激各种心血管重塑相关基因如转化生长因子-β1(TGF-β1)、Ⅰ，Ⅲ型胶原、骨骼肌α-actin、β-MHC(β-myosin heavy chain，β-肌球蛋白重链)、心钠素的表达。

Moreover, Id1 can antagonize the Ets2-mediated transcriptional activation of target genes.

该家族的Id1还可拮抗Ets2的转录激活作用。

Inhibitory effect of arsenious acid on expression of HIF-1α. in human hepatocellular carcinoma HepG2 cells were through post-transcriptional mechanisms.

亚砷酸抑制人肝癌细胞HepG2中HIF-1α蛋白表达是通过转录后机制。

This study was aimed to find single nucleotide polymorphism in the promotor region of asparagine synthetase gene and to determine if these SNPs have influence on the transcriptional activity of AS promotor.

本研究旨在通过筛查发现AS启动子区的单核苷酸多态性位点，研究它们对AS基因表达量的影响及寻找对Lasp治疗反应具有影响的个体遗传因素。

in order to establish a rapid, sensitive and specific detection method for identification of four kinds of food-borne pathogenic bacteria including salmonellla spp, listeria monocytogenes, staphylococcus aureus and bacillus cereus by using multiplex pcr, according to invasion protein a geneof salmonellla spp, transcriptional regulatory protein gene of listeria monocytogenes, autolysin gene ofstaphylococcus aureus and gyrase b subunit gene of bacillus cereus, four pairs of specific primers were designed for multiplex pcr amplification.

小 摘要：为建立一种利用多重pcr技术检测和鉴定沙门氏菌、单核细胞增生李斯特菌、金黄色葡萄球菌和蜡样芽孢杆菌的方法，根据沙门氏菌侵袭力蛋白a基因、单核细胞增生李斯特菌蛋白转录调控基因、金黄色葡萄球菌自溶素基因、蜡样芽孢杆菌的促旋酶b亚单位基因设计引物，进行多重pcr扩增，并对多重pcr反应体系进行优化。

This indicates that the expression of GS in sugar beet is regulated at transcriptional and translatable levels.

说明甜菜GS的表达可能在转录水平和翻译水平上均受到调控。

Transcriptional regulation is one of main machnisms of the expression of COX-2, which is regulated by transcriptional factors.

转录水平的调节是COX-2基因表达调节的主要机制之一。

Auxin-dependent TIR1 activity leads to ubiquitination-based degradation of transcriptional repressors and complex transcriptional reprogramming.

依赖于生长素的TIR1活动导致转录抑制子和复合体转录重新编程的泛素化基础的退化。

Reporter gene assays showed that ZNF325 and ANKZF1b both are transcriptional repressors because overexpression of ZNF325 and ANKZF1b in the COS-7 cells inhibit the transcriptional activities of AP-1 and SRE.

ZNF325转录活性的拆片分析和RNAi分析进一步证明C2H2锌指区域对报告基因AP-1和SRE起着重要的抑制作用。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。