查询词典 transcriptional

Bioinformatics methods were used to analyze the transcriptional patters and promoter of defensins gene family in Anopheles gambiae .

运用生物信息学方法分析冈比亚按蚊中防御素基因家族的表达模式和启动子保守区。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase II detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白-1 (Kelch-like ECH-associated protein-1， Keap1)可将Nrf2与肌动蛋白细胞骨架一起收集在细胞质内，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1脱离，进入细胞核并与ARE结合，从而激活多种抗氧化基因和II相解毒基因的转录。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase Ⅱ detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白－1(Kelch-like ECH-associated protein-1， Keap1)与Nrf2耦联，并与肌动蛋白细胞骨架结合被锚定于胞浆，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1解耦联，进入细胞核并与ARE结合，从而激活多种抗氧化基因和Ⅱ相解毒酶基因的转录。

In response to extracellular stimuli, ERK1/2 translocates to nucleus, phosphorylates transcription factors,such as Elk1,ATF2,Sap-1α,c-myc,STAT, and so on, co-regulators and chromatin proteins to initiate transcriptional changes.

斑点杂交研究发现Ngb mRNA在大脑皮层、海马和丘脑等部位表达，缺血缺氧可使Ngb mRNA表达上调，其表达上调程度与相应区域对缺血缺氧的耐受性呈正相关。

The less of E-cadherin in leukemia cells may result in β-catenin translocating to the nu-clear and transcriptional activation of its target genes.

白血病细胞中E-cadherin表达降低或缺失可引起β'-catenin从细胞膜释放并进入细胞核，最终可能会引起β-catenin靶基因的转录。

Transcriptional feedback loops constitute the molecular circuitry of the plant circadian clock.

转录反馈回路构成了植物生物钟的分子线路。

As it features high conservation, the DREB transcriptional factors and the signal pathway are significant in improving crop drought tolerance and understanding the cross talk of signal pathways.

由于DREB转录因子以及这一信号途径在各种植物中具有很高的保守性，研究这一信号途径对于改良作物的耐旱性以及了解植物抵御干旱的信号交叉联系具有重要意义。

After three months, gained blood from cardinal vein and detected the level of serum E2; put all rats to death and got femur bone tissue with asepsis condition. Detected the transcriptional level of PTHR1 gene with RT-PCR. And detected the expression level of PTHR1 protein with Western blot. Results: In ovariectomized groupthe level of serum E2 was 13.80±1.10 pmol/L, the E2 of model control group was 23.51±1.20 pmol/L.

术后3个月腹主静脉取血，测定各组大鼠血清E2水平；分别用小动物骨骼强度测定仪和双能X线骨密度仪检测右股骨生物学力学和骨密度；从左股骨中提取总RAN和总蛋白，分别检测PTHR1在转录和翻译水平上的变化。

Taken together, these observations suggest that one or more CREB-like transcriptional activators are required for long-term facilitation.

总之，这些发现表明长期促进作用依赖一个或多个类似CREB的转录激活因子。

CEAS helps the adoption of ChIP-chip in mammalian systems and provides insights towards a more comprehensive understanding of transcriptional regulatory mechanisms.

CEAS帮助在哺乳动物系统中采用ChIP-chip并提供了对转录调控机制的一个更全面的理解。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐