查询词典 transcription

Dysfunctions of transcription factors, which are key elements in the regulation pathways, are involved in numerous pathologies.

调控通路中关键因素----转录因子的功能失调涉及到很多疾病。

Here, using a strategy of re-expressing key developmental regulators in vivo, we identify a specific combination of three transcription factors Ngn3 (also known as Neurog3 Pdx1 and Mafa that reprograms differentiated pancreatic exocrine cells in adult mice into cells that closely resemble beta-cells.

这里，在体内通过一种策略将生长发育中关键的调控因子进行再表达，我们鉴定出了一系列3个转录因子（Ngn3 (亦称 Neurog3)，Pdx1 和 Mafa），将它们重组入成年小鼠的胰腺外分泌细胞，相应的细胞可分化成类似于β细胞的细胞。

As RNA polymerase moves along the DNA template, it unwinds the duplex at the front of the bubble, and rewinds the DNA at the back. The length of the transcription

当RNA聚合酶沿DNA模板移动时，它打开泡前的DNA双螺旋，并在复链点使DNA复原，转录泡的长度随增长反应阶段而异，在12-20bp之间，但其中的RNA-DNA杂交体区域比这个长度要短。

They were randomly scarified at 3, 6 and 9 weeks after injection of CCl4 respectively. Their liver tissues were analyzed for histopathological changes. Gene expression of p38MAPK was measured by reverse transcription-PCR and immunohistochemistry was used to detect the protein expression and localization.

取其肝脏观察HF形成过程中不同时间段各组大鼠肝组织病理变化，用RT-PCR技术检测p38MAPK mRNA在造模过程中肝组织中的表达变化，免疫组化方法检测p38MAPK在造模过程中肝组织中蛋白表达量的变化，及其在肝组织中的表达分布情况。

Thirty two male SD rats (weight 250~300g) were randomly scarified 1, 4 and 8 weeks after injection of CCl4 respectively, and their liver tissues were used for examining CTGF by immunohistochemistry stain, reverse transcription polymerase chain reaction and western blot.

雄性SD大鼠32只，体重250~300g，皮下注射四氯化碳(CCl4)制备大鼠肝纤维化模型，分别于注射后1、4、8周处理动物，采用免疫组化、RT-PCR、Western blot等方法对肝组织中CTGF的表达进行检测。

Transcription, and analyzes Wangs inheritance, reproduction and development of Chinese ethical folk music. She also makes transverse comparisons between the musical forms of piano works by composers of both China and abroad, and illustrates that Wang uses for inference but not copies the western musical forms, that he attaches importance but not stickles to the framework of traditional Chinese music, and also that he demonstrates a characteristic of not sticking to one pattern. She makes contrastive comparisons as well of the melodies and harmonies of piano works by composers of both China and abroad, and indicates that in inquiries into the folk style of counterpoint, Wang is flexible and creative in harmonies by inheriting the character of a clear melody and the method of multi-voice in Chinese traditional music and also by absorbing the character of emphasizing the layers of texture in western piano music.

拿民族民间音乐与钢琴改编曲作纵向比较，分析其对中国民族民间音乐的继承再现与发展；拿中外钢琴作品的曲式原则作横向比较，说明他借鉴但不照搬西方音乐曲式规范，重视但不拘泥于传统中国音乐结构方法，在作品的结构上，呈现出不拘一格的特点；拿中外钢琴作品在旋律、和声等方面作相异比较，指出了在探索多声部音乐的民族风格过程中，王建中一方面继承了传统音乐中旋律线条十分突出的特点，另一方面又吸收了西方钢琴音乐注重织体的网状结构的特点，有意识地运用了我国民间多声手法，在和声的运用方面表现出灵活多样而又富于创新的特点。

In this thesis, based on a recent genome-scale dataset of DNA methylation in human brain tissues, we developed a classifier for predicting methylation status of CpG islands using a Support Vector Machine. Nucleotide sequence contents, transcription factor binding sties and Alu repeats are used as features for the classification. The method achieves accuracy of ~85% on the brain data.

本文的主要工作就是基于人脑测得的DNA甲基化数据，挖掘DNA序列特征，用支持向量机的方法实现了预测CpG岛甲基化的目标，得到了85%的预测正确率，同时还验证了所选的三类特征对于CpG岛甲基化的指导作用，它们分别是DNA序列组合、转录因子结合位点TFBS和短重复序列Alu。

At first one tends to assume that a transcription of a tape-recorded interview of an eyewitness would be a very accurate record of an event.

首先，（0）人们都倾向于假设，（对一个目击者的采访录音的抄写本），应该是一个事件的非常准确的记录。

The DNA sequences corresponding to the 3'terminuses of HCV genotype 1a, 1b and 2a negative RNA strand were cloned to the transcription plasmid pGEM3Zf.

以1a型负链3'末端RNA为模板，NS5B1和NS5B2为聚合酶，进行体外的RNA合成反应，斑点杂交和RT-PCR检测产物，确定纯化的蛋白具有RdRp活性。

The 3'terminuses of negative RNA strand from 1a, 1b and 2a were prepared via in vitro transcription, using these RNA as temlates and the two purified NS5B proteins as polymerase respectively we conducted the RdRp assay in vitro.

分别以体外转录的HCV 1a、1b和2a型负链3'末端RNA作为模板RNA，NS5B1和NS5B2为聚合酶进行体外RdRp反应，Northern blot检测产物合成情况。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。