查询词典 transcription

Histone acetyltransferase CBP/p300 remodels chromatin by acetylating histones resulting in open structure of chromatin and active transcription.

转录辅因子CBP／p300本身具有组蛋白乙酰转移酶活性，参与许多基因的转录调控过程。

Methods After treated with a specific demethylating agent,Aza and acetylating agent, TSA, the status of 5'CpC island methylation of ING1b gene in HT29 human colon cancer cell line was analyzed using methylation specific polymerase chain reaction,and the level of histone acetylation was analyzed by chromatin immunoprecipitation,and reverse transcription polymerase chain reactionwas used to examine ING1b mRNA expression.

应用特异性DNA甲基转移酶抑制剂5-氮-2'-脱氧胞苷（5-Aza-2'-dc，以下简称Aza）及组蛋白去乙酰化酶抑制剂曲古抑菌素A作用人结肠癌细胞株HT29后，用甲基化特异性PCR检测该ING1b基因核心启动子区域CpG岛甲基化情况，用染色质免疫沉淀检测其乙酰化组蛋白绑定的DNA情况，并用逆转录聚合酶链反应检测ING1bmRNA表达。

In summary, the BRD7 gene acted as a candidate of tumor suppressor gene with NPC. The overexpression of BRD7 can partly reverse malignant phenotype of NPC cell line. The suppression effect of BRD7 on NPC tumorigenesis my be achieved by recognizing acetylated histone peptide through their motif-bromodomain, then modulating gene transcription by taking part in histone acetylating and chromosome remodeling, finally influencing signal-transduction pathways.

综上所述，BRD7基因作为一个重要的鼻咽癌抑瘤基因侯选者，在鼻咽癌细胞中的过表达后，可导致鼻咽癌细胞 HNE蛋白质表达谱发生改变，逆转其恶性表型，其作用机理可能是：BRD7基因通过其功能域彭聪硕士学位论文10Bromodomain与乙酚化的组蛋白特异性结合，参于染色体的乙酚化，染色质的组装，从而影响基因转录的调控，最终影响细胞内的信号传导通路并实现对细胞周期的调控，从而发挥抑制鼻咽癌细胞生长的作用。

Ulcer index and serum cortisol level were used to evaluate the protective effect of acupuncturing at the acupoint ST 36; reverse transcription-polymerase chain reaction was used to detect the expression of SP and POMC in hypothalamus and adrenal, and the images were analyzed with semi-quantitative method.

胃黏膜溃疡指数和RT-PCR法研究针刺足三里对大鼠的冷应激性溃疡的保护作用和下丘脑、肾上腺的SP、POMC的表达，经图像分析系统照相并进行半定量。

The essence of differential display method is to use for reverse transcription an anchored oligo-dT primer which anneals to the beginning of a subpopulation of the poly tails of mRNAs.

该差异显示方法的本质是使用为反转录一锚定寡脱氧胸苷引物的退火的一个聚尾巴 mRNA的。

Systematically identifying and annotating transcription factors can greatly aid further understanding their functions and mechanisms.

系统性的识别和注释转录因子能够极大的促进进一步理解它们的功能和机制。

Citadel. Guzbah wanted a transcription of the epic poem of Aegwynn. Lady Delth declared that sherecognized none of the titles he sent her-could he send them again, this time with the first paragraph ofeach, so she knew what they were? And Alonda was adamant that there had to be a fifth breed of troll,and that Khadgar had obviously not found the proper bestiaries. The young mage was delighted to leave

信中是对他上一次报告的回复：贾兹巴希望他能给他寄去一份艾格文史诗的抄本，戴尔斯女士在信中说她根本不了解那些书在讲什么，并询问卡德加可否在每个书目下摘抄一段文字再给她邮去，奥蓉达则坚信世界上存在第五种巨魔，认为卡德加没仔细看完所有的怪物手册。

The services provides transcription services, translation and captioning services for everyone, from individuals needing one-time services to the world's largest companies.

我们为小到个人的单次服务到大公司的誊写服务，翻译服务和字幕翻译服务。

A polymerase that catalyzes the formation of RNA from a DNA template in the process of transcription.

在提炼油页岩的过程中回收的硫酸氨液比过去多了。

A polymerase that catalyzes the formation of RNA from a DNA template in the process of transcription.

一种催化rna模板上的dna形成的聚合酶，尤其在逆转录酶病毒中发现。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。