查询词典 transcription

As we know, SWI/SNF is a global, untargeted chromatin remodeler which influence transcription, it perform gene-specific regulation by interacting with some selective activators. On the other hand, no known DNA-binding domain is found in BEX1. So we come to a conclusion that BEX1 may mediate activators interact with hSNF5, and this result in the transcription of specific sets of genes that control the cell cycle.

由于BEX1本身并未发现能与DNA直接结合，而hSNF5所在的染色质重塑复合体单独存在时作用没有特异性，我们推测，BEX1可能作为接头分子，介导了其它蛋白与hSNF5的作用，导致控制细胞周期相关基因的转录激活或抑制。

In the feedback regulation system of choles-terol metabolism, SCAP together with membrane-bound transcription factors - sterol regulatory element-binding proteins control transcription of the genes encoding enzymes of choles-terol and fatty acid biosynthesis.

在胆固醇代谢的反馈调节系统中，SCAP与膜结合转录因子胆固醇调节元件结合蛋白(sterol regulatory element binding proteins；SREBPs)等调节因子，共同控制一系列酶编码基因的转录过程，包括胆固醇和脂肪酸生物合成过程中所需的酶。

Results: As the concentration of cobaltous chloride increased, the LDH and the promoter transcription activity were also increased. Furthermore, there was a tendency that the transcription activity increased as time lasted.

结果：氯化钴刺激下HUVEC-12细胞培养上清的LDH含量随氯化钴作用浓度增加而提高；氯化钴刺激后转染细胞的eNOS启动子活性呈现随氯化钴剂量增加而升高的趋势，随作用时间的延长而上升的趋势。

The embryonic analysis results indicated that the disruption of oxt gene would lead to the disruption of wg transcription and the expression of engrailed gene, as the wg transcription is dependant on the Engrailed.

进一步结合运用FLP-FRT系统，用缺损GFP蛋白的表达来标记纯合的oxt突变基因克隆，针对眼睛成虫盘的克隆分析结果表明，在oxt突变克隆中，Hh下游的Ci蛋白的表达区域完全消失。

However, with the development and the application of new techniques, the reliability of the methods used in the research of the transcription site of RNA polymerase I was doubted; and also, some indirect results indicated that the transcription of RNA polymerase Ⅲ might occur in the nucleoli.

但随着新的研究技术的发展和应用，人们对RNA聚合酶Ⅰ转录位点的早期的研究方法的可靠性提出质疑；同时，根据一系列间接的实验推论RIgA聚合酶Ⅲ的转录可能发生在核仁中。

To minimize cellular variations, we generated stable cell lines for firefly luciferase reporters, and used Renilla luciferase-fused transcription factor to measure the quantity of individual transcription factor.

为了将细胞的变化值减到最小，我们设计了带有firefly luciferase reporters稳定细胞株的建立，并且利用fusion protein(同时带有Renilla luciferase与转录因子构筑融合蛋白)去计算出单独转录因子的数量。

The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser CTCF, and kruppel-like zinc finger protein; two members of the ADAMs (a disintegrin and metalloprotease domain) family; two members of integrin family; several proteins involved in the signal transduction, cell-cycle control, chromatin remodeling and transcription repression; and also some proteins of cell skeleton and some with unknown functions.

鉴定出 的蛋白包括多个与转录调控相关的锌指蛋白，如锌指蛋白198、263、14、224、zf6、转录抑制因子cTcF样蛋白、幻肚pple样锌指蛋白等：两个含金属蛋白酶结构域和整合素结合结构域的家族成员ADAM28和ADAM17；两个整合素家族成员pZ整合素和含十个EGF样结构域的整合素；与细胞信号转导通路有关的蛋白；与细胞周期调控有关的蛋白；与染色体重塑和基因转录抑制有关的蛋白；细胞骨架蛋白以及其他功能未明的蛋白等。

To determine the regulating role of mtlR in transcription of mannitol PTS operon in V.cholerae,and whether it plays a role in the ferment difference of the toxigenic and non-toxigenic strains,the mtlR deletion mutants from the mannitol rapid-ferment strain(non-toxigenic strain) and slow-ferment strain were constructed.Comparisons of the growth in M9 containing 0.2% mannitol as the sole carbon source and pH change in mannitol fermentation media of these wild strains and their mutants,indicated that mtlR is a repressor.Its repression in mtlCBA transcription was further verified with the analyses of quantitative reverse-transcriptional PCR.

通过比较快发酵菌株和慢发酵菌株mtlR缺失突变株与野生株在含0.2%甘露醇的M9培养液及甘露醇发酵液中生长、产酸等的变化，定性地证明了mtlR基因的抑制作用；另外通过定量RT-PCR进一步验证了MtlR蛋白在mtlCBA转录水平发挥负调控作用。

TaYAB1 and TaCRC may play important roles in transcription and transcription regulation during the establishment of abaxial-adaxial polarity in wheat.KeywordsWheat;YABBY gene family;TaYAB1;TaCRC;Bioinformatics

本研究以TaYAB1与TaCRC为研究对象，利用生物信息学方法，对这2个基因编码的蛋白结构与功能进行预测，同时构建其同源基因的系统进化树，从而为揭示小麦侧生器官背腹极性建立的分子机理提供重要资料。

The histone octamer may protect the wrapped DNA from interacting with other environmental factors such as transcription regulating proteins, thus the positioning of nucleosomes along DNA may play important roles in multiple cellular processes including DNA replication, transcription and damage-repair.

由于核小体结构中的DNA缠绕在组蛋白八聚体上，可能影响这些DNA与细胞内的其他蛋白相互作用，从而影响到DNA复制、转录等生物学过程，因此，核小体在基因组上的位置分布可能对基因组功能具有重要的调控作用。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。