查询词典 transcription

It is reported that KAP-1 related transcription regulation complexes exert functions essen-tial for spermiogenesis and early embryo development. This regulation is one pattern of epigenetic regulations.

KAP-1参与形成的复合体在精细胞发育、胚胎早期发育等生理过程中发挥重要的调控作用，这种调控属于表观遗传调控范畴。

Most of the imprinted genesthat have been studied are regulatory: transcription factors, alternative splicer, tumorsuppressors, growth factors, or are involved in complex signal pathways.

基于印记基因在生长和发育中的重要调控作用，预测这些基因可能对猪等家畜动物的生产性状产生较大的影响。

The first part of this paper is to set up a novel mathematical model describing expression and regulation of trp operon, in which not only the effects of repression and attenuation on transcription are taken into consideration, but the interaction between repression gene and structural gene as well as the transportation of tryptophan across cell membrane are also considered.

论文第一部分主要在已有的色氨酸操纵子模型基础上，建立了一个新的用于描述色氨酸操纵子动态行为的数学模型，它不仅考虑了阻遏、弱化以及反馈抑制作用对转录的影响，而且考虑了表达阻遏蛋白的基因和表达关键酶的基因之间的相互作用和影响，以及色氨酸外排的影响。

The objective of this study is to picture the signal tranduction pathway of apoptosis induced by MC so as to further investigate the impact of MC on transcription, expression and regulation of apoptosis gene and the related biological effects; illustrate the toxicological mechanism of MC; as well as discover the new biomarkers invovled.

本研究工作的目的是通过功能基因组分析的技术平台，探讨微囊藻毒素诱导肝组织细胞凋亡的信号转导通路，以便在此基础上，进一步深入研究该毒素对凋亡功能基因在转录、表达、调控水平上的影响，及由此引发的生物学效应；揭示微囊藻毒素的凋亡毒理机制，同时发现新的生物标记物。

Transferred the NP-1 gene into C. ellipsoidea by electroporation with high efficiency expression vector pBinUΩNP1. PCR, Southern blot and Northern dot blot analysis of the G418resistant alga strains indicated the stable integration and correct transcription of NP-1 in C. ellipsoidea genome. In vitro antagonistic assays showed the proper expression of defense gene in C. ellipsoidea. Transgenic C. ellipsoidea is antagonistic to gram negative bacteria—Bacillus subtonic, gram positive bacteria—Escherichiacoli and fungi—Fusarium oxysporum to some extent.

以椭圆小球藻完整细胞为受体，采用电激转化法将连接在高效表达载体pBinUΩNP1上的兔防御素NP-1基因导入小球藻，通过PCR、Southern杂交、Northern点杂交对转基因小球藻进行了分子检测，同时通过体外离体抑菌实验检测了兔防御素NP-1基因表达产物的活性，结果表明NP-1基因已稳定整合到小球藻基因组中，并进行了正确转录和表达。

Ritossa the first to discover super-normal temperature environment can cause the phenomenon of chromosome fluffy with gene transcription activity, known as heat shock phenomenon.

急求！！英语高人帮忙翻译下这篇分子生物学的文章啊1962年，Ritossa首先发现超常温环境可引起染色体发生蓬松现象并具有基因转录活性，称之为热休克现象。

WRKY is a superfamily of transcription factors in the high plant, and there are many genes in it.

WRKY转录因子在高等植物中形成一个庞大的基因家族，基因数量众多。

The regulation of gene expression is to have relations to the assembly of the DNA binding proteins which bind to DNA to initiate the transcription. Some of these proteins have the ability to promote bending or looping of DNA. The FIS protein regulates gene expression in Escherichia coli by this property of bending DNA. There are many researches to discover the mechanism of FIS protein binds to DNA. However the experiment data only show the supposititious results and figure out the model of FIS-DNA complex structure. This research uses molecular dynamics simulation to compute the detail of the interaction between FIS and DNA. We observed FIS prominently affects the DNA bending by the type of local bending. Analyzing the DNA structure properties, roll and slide, also demonstrates the local bending type and region. The hydrogen bonds between FIS and DNA are analyzed to compare with the experiment data. Finally we compute the binding free energy between FIS and DNA to estimate the result of simulation and compare with the value of λ-repressor-DNA complex.

基因的表现与结合於DNA促使DNA转录作用起始的DNA结合蛋白组装有关，一些这类的蛋白质具有促使DNA扭曲或将DNA形成环状的能力，FIS蛋白质即是藉由扭曲DNA的特性调控大肠杆菌基因的表现，目前已有很多的研究发现FIS与DNA结合的机转，然而这些实验的数据仅能显示推测性的结果，进而利用这些结果推论出FIS与DNA聚合体结构的模型，本研究利用分子动态模拟的方式计算FIS与DNA交互作用的细节，我们观察到FIS主要影响DNA的扭曲方式为DNA区域扭曲的类型，并且分析DNA结构特性roll与slide也指出扭曲方式为区域扭曲与其扭曲的区域，我们也分析FIS与DNA之间的氢键，并且与实验的资料作比较，最后我们计算FIS与DNA之间的结合自由能评估模拟的结果，并且计算出的值和λ-repressor与DNA聚合体结构的实验值作比较。

Abstract］objective: effects of a single period of mechanical strain on gene expression patterns of two osteogenic transcription factors, ets1 and cbfa1, in rat calvarial sutural osteoblast-like cells were studied in this study to elucidate the molecular mechanism of suture distraction.

摘要］ 目的：探讨大鼠颅骨缝成骨细胞在张应力作用下ets1和cbfa1基因表达的变化，以揭示骨缝牵张成骨的分子机制。

Objective: Effects of a single period of mechanical strain on gene expression patterns of two osteogenic transcription factors, Ets1 and Cbfa1, in rat calvarial sutural osteoblast-like cells were studied in this study to elucidate the molecular mechanism of suture distraction.

结果：Ets1和Cbfa1的mRNA水平分别在机械张应力作用后6 h及12 h内显著增高，随后，mRNA水平逐渐恢复到对照组水平，Ets1先于Cbfa1表达，在加力后表达立即升高，并在0.5h达到最高水平，而Cbfa1则首先经历一个短暂的潜伏期，后表达逐渐升高，在6 h达到最高水平，Cbfa1的最高表达水平约为Ets1的2.58倍。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。