查询词典 transcription

Besides, HIF-1 can quickly induce a lot of expressions and the adjustment of anoxia-induced genes, so as to enhance the hypoxia-induced genetic transcription and increase the expressions, and engender physiological effects, such as adjusting the transcription of EPO genes to increase their production, thereby the red blood cells quantity is enlarged, which strengthens the ability of oxygen transportation and mitigates anoxia; adjusting VEGF genetic transcription to engender more blood capillaries, consequently the transportation and supply of oxygen and substance of energy source are strengthened; adjusting the glycolytic enzyme to enhance glycolysis ability under anoxemia condition and increase energy supply; functioning on HO-1 genes in vascular smooth muscle cells to produce HO-1, which can engender NO and CO as pneumatic signal molecules to activate the guanylate cyclases, thus CGMP level is improved to make the vascular smooth muscles chalasia, to restrain platelet agglutination, so that theblood flow and vascular permeability are increased, and the anoxic tissues obtain ample oxygen supply, etc..

在低氧环境中，HIF-1可以被很快诱导大量表达并介导低氧诱导基因的调控，使低氧诱导基因转录增强，表达产物增多，产生生理效应。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

However, plastids only have a semi-autonomous transcription and translation machinery. The transcription of endogenous plastid genes is largely dependent on nuclear-encoded transcription factors.

然而， 质体仅具有半自主性转录和翻译机制，其内源基因的转录要依赖于核基因编码的转录因子。

In fish and amphibia, the transition from maternal gene transcription to zygotic transcription happens during the time of midblastula formation, this stage is named by midblastula transition, at this period, embryo cell cycle composition changes, it is the first time to G1 time appearance, the cell cycle timelimit lengthens and the cell division synchronism loses, the large quantities of zygotic gene transcription starts.

鱼类和两栖类由母型调控向合子型调控过渡发生在中囊胚形成阶段，称为中囊胚过渡(midblastula transition，MBT)，胚胎细胞周期时相的组成在此期间发生变化，首次出现G1期，周期时限延长，细胞分裂的同步性丧失，大批合子型基因活化转录也在此时开始。

Since acetylated histones are associated with activation of gene transcription, we further investigated the transcription factor levels by transcription factor array.

因为乙酰化组蛋白与基因转录的活化有关联，我们进一步进行了转录因子水平的研究。

Based on establishment of the human macrophage-derived foam cell model, the expression of Kv1.3 channel was investigated by immunocytochemical staining, reverse transcription-polymerase chain raction and Western blot. Furthermore, the effects of rMargatoxin, a Kv 1.3 channel-specific inhibitor, on cholesterol metabolism in macrophages incepting oxidized low density lipoprotein were studied.

在建立人巨噬细胞源性泡沫细胞模型的基础上，采用免疫细胞化学染色法、逆转录聚合酶链反应(transcription-polymerase chain raction，RT-PCR)及Western blot，研究Kv1.3通道的表达，并观察其特异性阻断剂--rMargatoxin对摄取氧化修饰低密度脂蛋白的巨噬细胞胆固醇代谢的影响。

OBJECTIVE: To explore the expression and significance of signal transducers and activators of transcription 3(STAT3) in laryngeal squamous cell cancer.

目的： 研究信号转导与转录活化因子3(signal transducers and activators of transcription 3， STAT3)在人喉鳞状细胞癌组织中的表达，探讨其在喉癌发生发展中的作用。

Orthographic representation of speech sounds –broad and narrow transcriptions 语音的书写形式-宽式和窄式音标 IPA-International Phonetic Alphabet 国际音标 There are two ways to transcribe speech sounds. One is the transcription with letter-symbols only, called broad transcription. The other is the transcription with letter-symbols together with the diacritics, called narrow transcription

窄式音标。实例：对 pit/spit 中 p 音的比较： pit 中的 p 是送气音，在窄式音标中标为上标，写作： spit 中的 p 是不送气音，在宽式音标中不作标示，写作：对 leaf/feel/build/health 中 l 音的比较： Leaf 中 l 在元音前，叫清晰音，在宽式音标中不作标示，写作： Feel 中 l 出现在单词结尾，叫模糊音，在窄式音标中加变音符号 Build 中 l 出现在另一个辅音前，也叫模糊音，在窄式音标中也加变音符号 Health 中 l 出现在齿音前，受其影响叫齿音，在窄式音标中加变音符号 5。

The results showed that the ZNF191fu and ZNF434fu functioned as transcription repressors while the ZNF396fu can only weakly suppress the transcription activity of the reporter, and the ZNF397fu and ZNF447fu showed no signanificant capability of transcription regulation.

而转录因子发挥作用需要进入到细胞核中，因此，我们进一步分析了这些基因的不同剪接本在细胞内定位的情况，结果显示我们所检测的5个成员的nf剪接本都能被相应的fu剪接本带入细胞核内，并且这种作用是通过SCAN结构域所介导的。

The principal level for controlling gene expression is at transcription and the regulators of transcription are often DNA binding proteins that activate transcription at particular promotors or other regulator...

基因表达的调节主要在转录水平上进行，并且转录调控子多是一类DNA结合蛋白，通过其与受控基因启动子或其他调控元件的结合来调节目标基因的表达。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。