查询词典 trail

TRAIL interacts with an unusually complex receptor system of two DRs and three decoys at tumor cell membrane.

和TNF家族的其他成员不同的是，TRAIL在体内仅以膜结合型存在。

It is one of the key pathogeneses of postmenapausal osteoporosis that estrogen deficiency leads to the decrease of OPG、TGFβ expression and the increasing expression of some bone-resorbing cytokines as OPGL、M-CSF and TRAIL, then stimulates osteoclast differentiation and activity, which potentiates bone resorption and bone loss:(2) ICI182780 shows partial transactivating function in osteoblasts, so it should belong to a kind of selective estrogen receptor modulators .

雌激素缺乏可能导致HOB中OPG、TGFβ的表达减少，而解除了对OPGL、M-CSF和TRAIL等刺激OC生成和活化的细胞因子的抑制作用，OC的数量和活性增加，导致骨吸收增强和骨量丢失，这是导致绝经后骨质疏松症的一个重要的发病机制；ICI182780在成骨细胞内表现出促转录活性，因此它并非纯ER拮抗剂，而应属于选择性雌激素受体调节剂(selective estrogen receptor modulator，SERM)。

Our previous study and others reports shoed that, the sensitivity of tumor cells to TRAIL may be related with endogenous NF-κB expression.

根据其他文献与本实验室先前的研究结果显示，癌细胞株NF-κB蛋白的活性高低与TRAIL抗药性的表现有密切的关联。

Methods The Fas, FasL and DR4, DR5, TRAIL were assessed in 45 normal cervices, 52 cervical intraepithelial neoplasia gradeⅢ and 51 cervical cancers by immunohistochemical method. The number of apoptotic cells was determined by morphological criteria and the number of proliferating cells by counting Ki-67-positive cells. Results Proliferation and apoptosis percentage was markedly increased with increasing severity of neoplasia.

应用免疫组织化学法检测45例正常宫颈组织、52例宫颈上皮内瘤变Ⅲ级(cervical interaepithelial neoplasia Ⅲ， CINⅢ)和51例宫颈鳞状上皮细胞癌组织中Fas、FasL、DR4、DR5、TRAIL的表达，并以显微镜定位表达位置，以Ki-67阳性细胞记数增生细胞数。

Methods: The level of TRAIL, the proliferation index and apoptosis rate were detected by flow cytometer analysis in 23 case of hemangioma at proliferating phase, 20 cases of hemangioma at involuting phase, and 15 eases of normal skin.

应用流式细胞术检测23例增生期、20例消退期血管瘤和15例正常皮肤组织中TRAIL蛋白的相对含量，细胞增殖指数和细胞凋亡率。

Results: In hemangioma at proliferating phase, hemangioma at involuting phase, and normal skin, the expressions of TRAIL were 1.26±0.56, l.74±0.68, and 1.00±0.23, PI was (40.98±12.02)%,(20.05±3.67)% and (15.64±4.01)%, AR was (11.96±4.02)%,(20.29±3.53)% and (6.61±1.29)%, respectively. There were significant differences among the 3 groups in the 3 parameters.

结果：增生期血管瘤、消退期血管瘤和正常皮肤组织中TRAIL蛋白的表达分别为1.26±0.56，1.74±0.68，l.00±0.23，PI分别为(40.98±12.02)%，(20.05±3.67)%，(15.64±4.01)%，AR分别为(11.96±402)%，(20.29±3.53)%，(6.61±1.29)%。3组间以上3指标两两比较，差异均有统计学意义。

The Company manages a portfolio of outdoor brands including Columbia Sportswear, Mountain Hardwear, Sorel, Montrail and Pacific Trail.

该公司经营的户外品牌包括Columbia Sportswear、Mountain Hardwear、Sorel、Montrail以及Pacific Trail。

Compared with the first quarter of 2007, first quarter 2008 outerwear net sales increased 16% to $69.6 million and accessories and equipment net sales increased 12% to $15.4 million. These increases were partially offset by a decrease of 1% in sportswear net sales to $161.1 million and a decrease in footwear net sales of 3% to $51.3 million.Compared with the first quarter of 2007, first quarter 2008 Columbia brand net sales increased 2% to $267.2 million, Mountain Hardwear brand net sales increased 23% to $21.8 million, and Sorel brand net sales increased 6% to $3.7 million. These increases were partially offset by a 20% decline in Montrail brand net sales to $3.9 million. Net sales of Pacific Trail brand products were insignificant during the first quarter of both years.

与2007年相比，2008年第一季度的服装净销售额为6960万美元，同期相比增长了16%；装备和配件为1540万美元，同期相比增长了12%；而运动服装为1.611亿美元，同期相比下降了1%；鞋类净销售额为5130万美元，下降了3%；Columbia 品牌的净销售额为2.672亿美元，同期相比增长了2%；Mountain Hardwear品牌的净销售额为2180万美元，增长了23%；Sorel的净销售额为370万美元，增长了6%；而Montrail的销售额为390万美元，同期相比下降了20%；Pacific Trail净销售额的增长情况在2007和2008年不是很显著。

Oncolytic adenoviral vector carrying human TRAIL gene holds great promising in cancer therapy.

携带人TRAIL基因的肿瘤特异性增殖型腺病毒在肿瘤治疗方面有着非常广阔的应用前景。

Make Chex Mix without the sugar, take the raisins out of the trail mix since your kid doesn't eat them, etc.

比如，你可以做不含糖的Chex Mix玉米片，还能把Trail Mix什锦杂果里的葡萄干都挑出来，反正你的孩子也不喜欢吃…。。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了