查询词典 torsade

While only a relatively moderate increase in the QT interval actually occurs with ziprasidone, because of the possibility of additive effects with some other drugs (and the attendant risk of torsade de pointes), to be on the safe side the makers of ziprasidone contraindicate its use with other drugs which can prolong the QT interval.

虽然真正由齐拉西酮引起的仅是相对适度的QT间期的延长，但因为有其他药物能引起累积效应的可能性(并有伴发扭转形室性心动过速的危险)，为了保障安全性，齐拉西酮的制造者们禁止将其与其他可延长QT间期的药物一起使用。

Objective To evaluate the effects of W-7, a calmodulin inhibiter, on transmural dispersion of repolarization, early afterdepolarization and torsade de pointes induction after administration of d-sotalol in isolated rabbit heart.

目的观察钙调蛋白拮抗剂W-7对离体兔心实验性尖端扭转型室性心动过速的影响，并探讨其机制。

Methods The data of 24 patients with LQTS and Torsade de pointed were summarized, the clinical manifestations and ECG characteristics were analyzed. Results Of 24 patients, 22 were females, 2 were males, the youngest was 9 years old.

回顾分析24例已确立诊断为长QT综合征和尖端扭转性室性心动过速的临床病例，对其临床和心电图特点进行分析。

The onset of torsade de pointes may differ among LQTS patients, being pause dependent in some but not all.

LQTS患者尖端扭转室速的发生可能各不相同，一些LQTS患者中存在间歇依赖性，但并不是全部LQTS患者。

The adverse side effects of drug may induce polymorphic ventricular tachycardia or torsade de pointes, which can increase mortality of the cardiovascular diseases.

从90年代CAST和CASTII试验结果公布以来，人们开始重视抗心律失常药物治疗的收益与风险评估。

Levofloxacin prolongs cardiac repolarization, a factor that is known to predispose to Torsade de Pointe, much more than moxifloxacin.

左氧氟沙星延长心脏的复极化，事实是都知道它可以预先用来治疗变异室性心动过速，要好过莫西沙星很多。

Part Ⅱ Effects of sex hormones on action potential and I〓、I〓 current in rat ventricular myocytes Objective To investigate effects of estrogen and androgen replacement on action potential and I〓, I〓 current in rat ventricular myocytes, from which to elucidate the ion mechanism of gender difference in torsade de pointes.

雌雄大鼠发生TdP的性别差异性与性别本身无关，关键在于性激素的差异，雌激素可通过使心肌细胞在复极延长的基础上EAD发生增加，导致触发活动，从而发生TdP；雄激素的作用则相反。

Background Long QT syndrome is a cardiovascular disease that causes syncope, seizure, and sudden death from cardiac arrhythmias, such as torsade de pointes, and ventricular fibrillation.

实验背景及目的 QT间期延长综合征患者可因严重的室性心律失常，如尖端扭转型室速、室颤而出现晕厥、抽搐。。。

Torsade de pointes is a kind of polymorphic ventricular tachycardia due to repolarization prolongation, it could induce cardiac sudden death, and set us an ever-increasing appreciation.

尖端扭转型室性心动过速(torsade de pointes，TdP)是一类与复极延长有关的多形性室性心动过速，可导致心源性猝死，正越来越引起重视。

Background Slowly activating delayed rectifier potassium currentI_(Ks is important in therepolarization of human cardiomyocyte action potential,especially in forming andmaintaining plateau of action potential. I_ channel is combined byαandβsubunits,which are coded by KCNQ1 and KCNE1 respectively. Mutations ofhKCNQ1/hKCNE1 genes,chronic myocardial hypertrophy and chronic heartfailure will lead to dysfunction of I_ and ingenital or acquired LQTS which areimportant factor in hazardous ventricular arrhythmia such as Torsade depoints.

实验背景缓慢激活延迟整流钾电流I_(Ks是参与人心肌细胞动作电位复极，特别是平台期形成与维持的重要外向离子流。I_通道由KCNQ1基因编码的α亚单位及KCNE1基因编码的β亚单位组成。hKCNQ1/hKCNE1基因突变或慢性心肌肥厚、慢性心力衰竭等病理过程均可导致I_功能异常，引起遗传性或获得性长QT综合征，LQTS易引起尖端扭转型室性心动过速等心律失常，从而危及病人生命。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐