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In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Zai is original in very Bacchic bazaar, if the advertisement sound that separates numerous medium is too big, can guide send aggravation of the environment that buy thing to cause client allergy thereby, if ad volume is too minor, effect of advertisement of You short of, which go is the person that bazaar buys thing dull to run to liquid crystal screen to fall to see ad?

在本来就很喧闹的商场里，分众传媒的广告声音如果太大，就会导致购物环境恶化从而引起顾客反感，如果广告音量太小小，又达不到广告效果，哪个去商场购物的人会无聊到跑到液晶屏下去看广告？

The relations of the ratio of density to the ratio of vertical height of the two kinds of particles are calculated, which shows that the main factor of granular oscillation is not the "Brazil nut effect" or "reverse Brazile nut effect".

通过计算在垂直方向上两种颗粒高度之比随颗粒密度的变化关系，说明决定颗粒振荡与否的主要因素并不是"巴西坚果效应"或"反巴西坚果效应"。

It was illuminated that the width of the centre bright fringe decreased along with the increasing width of the rectangular aperture when the effect of the aperture on the beam couldn't be ignored,however,the width of centre bright fringe step changed with increase of the size of the aperture when the effect could be ignorable,the width of the half maximum intensity of the centre bright fringe decreased along with the accretion of the width of the aperture and then it tends to a constant.

结果表明，当光阑对光束的衍射影响明显时，光束衍射场的中央亮条纹的宽度随着光阑边长的增大而减小；当光阑对光束的衍射影响极小时，中央亮条纹的宽度随着光阑边长的增加而阶跃变化，中央亮条纹强度的半最大值宽度随着光阑边长的增大而减小；当光阑对光束衍射影响极小时，中央亮条纹半最大值宽度趋近于一定值。

What we offer is the service that the car hires not just, combine travel market of the whole nation and look of the service that rent however, make from go vacationing, the complete travel that hotel, airline ticket rents maintenance to serve to car serves a system, provide the service of unifinication for consumer, the car on our net rented a service to had done near 2 years, dimensions of the platform that rent had reached countrywide each district source of carfare of home of many 60 illicit, if we rise these resource and travel market union, will form linkage effect.

我们提供的不仅仅是汽车租赁的服务，而是将全国的旅游市场和租赁服务相结合，打造一个从度假、酒店、机票到车辆租赁维修服务的完整的旅游服务体系，为消费者提供一体化的服务，我们的网上汽车租赁服务已经做了将近2年，租赁平台规模已经达到了全国各地60多万部私家车资源，假如我们将这些资源和旅游市场结合起来，将会形成联动效应。

Based on the the formal characteristics of "Lihe word"(another special disyllabic VO type structure in Mandarin),we found another important effect of nuclear stress,that is NS has the effect on syntactic structure to separate or conglutinate the combination of words within the NS domain, resulting the NS domain a expanding trend inside.

以该统计结果为基础，发现决定嵌偶词分布的条件是嵌偶词能否与邻近单音成分进行嵌偶，而制约嵌偶的规则有二：一是嵌偶的两个单音成分在句法结构上越近则越容易嵌偶；二是有"核心重音黏合力量"作用的两个成分容易嵌偶。

The analysis results show that the stability of long span curve continuous rigid frame is actually the ultimate load carry capacity considering the yield strength of material and the effect of the geometric nonlinear effect to structure can not be ignored.

结果表明：弯连续刚构桥梁的稳定问题已经转化为考虑结构材料屈服强度的极限承载力问题，同时几何非线性对稳定的影响亦不能忽略。

TG-DSC results revealed that the decomposition of magnetic CoAl HTLcs proceeded in two stages. The first large endothermic effect below 220℃involves the loss of physically absorbed and interlayer water and the second endothermal effect, between 220℃and 402℃, corresponds to the decomposition of the hydroxide layers and the removal of anions in the brucite-like layers. The S_ and pore diameter information of magnetic CoAl HTLcs were tested by N_2 adsorption-desorption analysis.

TG-DSC结果表明磁性CoAl水滑石有两个过程，在220℃以下的第一个失重过程是由于物理吸附水的移除造成的，在220℃至402℃之间的主要失重过程是由于材料脱除结构水，碳酸根离子和部分羟基造成，并伴随着层板结构的塌陷。N_2 adsorption-desorption测试分析了磁性钴铝水滑石的比表面积、孔径等信息。

A series of internal documents from the late 1970s and early 1980s shows that BAT at least thought about applying this knowledge to cigarette design. A research report from 1979 puts it thus: There are three major design features which can be used either individuallyorin combination to manipulate delivery levels; filtration, paper permeability, and filter－tip ventilation. A conference paper from 1983 says, The challenge would be to reduce the mainstream nicotine determined by standard smoking－machine measurement while increasing the amount that would actually be absorbed by the smoker. Another conference paper, from 1984, says:（5）We should strive to achieve this effect without appearing to have a cigarette that cheats the league table. Ideally it should appear to be no different from a normal cigarette...

英美公司上世纪70年代末、80年代初的一系列内部文献表明，该公司至少曾考虑过将这一知识用于卷烟设计。1979年的一份研究报告上这样说道：可分别或联合应用与设计有关的三个要素，即过滤、烟卷包装纸的通透性以及过滤嘴的通气效果，来控制焦油和尼古丁的释放水平。1983年一份会议论文也提到，关键在于，要在提高吸烟者尼古丁实际吸收量的同时，减少可被标准检测方法测定到的含量。1984年另一份会议论文说：我们应当努力达到这一效果并能在检测中蒙混过关。

Furfur. At the same time, selected the culture supernatant. Used the whole-fat-cow"s-milk plate method, the Folin-phenol method and the QuantiCleave proteinase Assay Kit to test the proteinase activity of mycelial phase and yeast phase of M. furfur. The effect of temperature and pH on this assay was also evaluated.Result:①The whole-fat-cow"s-milk plate method: Seven days after inoculation, the proteinase activity of the mycelial phase supernatant (12.5 ± 1.2mm) is higher than that of the yeast phase (9.25±0.71mm)(p.05); With the passage of the inoculation time, the proteinase activity of the mycelial phase is rising; the temperature has no obvious effect on the proteinase

结果：①全脂牛奶平板法：培养第7天菌丝相上清液蛋白酶活性(12.5±1.2mm)高于酵母相(9.25±0.71mm)(p＜0.05)；菌丝相上清液蛋白酶活性随培养天数延长而增大；25℃和37℃两种温度对上清液蛋白酶活性无明显影响(P＞0.05)；②Folin-酚法：上清液蛋白酶活性随培养天数、菌落计数、菌丝诱导率增加而增大，培养液pH值呈下降趋势；同一天的菌丝相上清液蛋白酶活性明显高于酵母相(p＜0.05)；三种温度(25℃、37℃、49℃)及三种pH值(3.8、5.6、7.4)对上清液蛋白酶活性无明显影响；温度37℃、pH5.6时菌丝相上清液蛋白酶活性最高；③QuantiCleave蛋白酶试剂盒：菌丝相及酵母相上清液中均含有蛋白酶且

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。