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Results: The growth of NB4 cells was inhibited significantly after treated with berbamine at different concentrations for different time points, the IC50 value was 3.860μg/ml at 48 hours. Morphology analysis showed the characteristics of apoptosis, and the DNA agarose electrophoresis showed the typical DNA ladder. The apoptosis rate increased from 2.83% to 58.44% after treated with berbamine at 12μg/ml for 18 hours. The expression of PML-RARα mRNA presented no significant changes, however, Survivin mRNA was decreased dramatically.

结果：经不同浓度小檗胺处理不同时间后，NB4细胞生长出现明显的抑制，并呈现明显的时间剂量依赖性，48h IC50为3.860μg/ml；细胞形态学观察可见细胞凋亡现象，DNA琼脂糖电泳显示典型的凋亡梯形图：流式细胞仪检测发现细胞凋亡率明显增加，经48h作用后，凋亡率从2.83%增至12μg/ml时的58.44%；虽未发现药物作用后PML/RARα基因表达量的改变，但检测到NB4细胞经药物作用后Survivin基因表达量的减少和Caspase3表达的增加，Caspse3阳性率从对照组的2.06%增至12μg/ml时的70.89%。

Results:!. General observation: The epithelization time of the wounds is in 15-20 days, 20 days after epithelization , the high of excess dermal scarring is as 3 times high as original ventol skin, color is pink, the blood vessel is abundant ; The scars begin to soften in about 60 days, the excess scarring can last nearly 100 days; The color and luster of scar after treating in Endostatin become light , the thickness is reduced, and become smooth.

结果：1。大体观察：瘢痕上皮化时间为15～20天，上皮化后20天瘢痕增生高度约为皮肤厚度的3倍，瘢痕约在60天开始自行退变软化，瘢痕增生维持状态最多持续时间达100天；经Endostatin干预后的瘢痕色泽变淡，厚度降低，瘢痕持续时间缩短，同期瘢痕面积小于对照组(P＜0.01)。2。

After heat treatment for 25h and 50h in air, the r phase showed an anisotropy on XRD pattern. The molar fraction of the r " phase formed at the interface between the substrate and the bond coat was calculated and the profile of composition of all elements was modeled after considering the change of heat treatment temperature and time.

多元合金的基体和热障涂层的扩散和界面反应，用相平衡热力学Thermo一ca1C和相变动力学D工CTRA软件对基体/底层界面Y'相的摩尔分数以及整个试样中各元素的成份分布随温度和时间的变化进行计算，计算结果与实验结果有很好的吻合。

Methods According to the 4×4 Latin Square design,lytic efficacy was assessed in UK dose[(10 000 U/ml,20 000 U/ml,30 000 U/ml or 40 000 U/ml)]and the timing of Uk infusion(2,4,8,16 h after blood sample taken)and UK lytic time(2,4,8,16 h after UK infusion)in vitro.15 rabbits were subjected to the intracerebral hematoma model for analysing the effect of 2 differents UK dose(10 000 U vs 30 000 U)on brain tissue around hematoma cavity.

目的 探讨尿激酶溶解血凝块的最佳用药剂量、用药时机及药物最佳作用时间，为临床一次性清除血肿提供实验依据。方法采用2个(4×4)拉丁方设计，分析UK剂量[(1万U/ml、2万U/ml、3万U/ml、4万U/ml)]、用药时机(抽血后2、4、8、16 h)和药物作用时间(加UK后2、4、8、16 h)对溶凝效果的影响。

If after being born, a brown-colored something was the first time you saw after opening your eyes, highly possible you'll like brown color in the future life.

如果出生时，你一睁眼正好看见咖啡色的东西，也许你就对咖啡色比较偏爱。

In 1 irrigation time and 2 irrigation times treatments, soil salt content decreased by 11.7%, and soil salt content increased by 12.6% in 3-4 irrigation times treatments. 2 After irrigation, the mean reduction of soil bulk density was 6.5%, and the mean increment of soil total porosity was 18.1%. With the irrigation frequency increasing, soil density was decreased and soil total porosity was increased. 3 Soil infiltration course of reed field irrigated by wastewater fitted Horton infiltration model well. After wastewater irrigation, the first infiltration rate decreased, but the stable infiltration rate promoted with the wastewater irrigation frequency increasing. 4 Soil water-holding capacity was increased by wastewater irrigation. The maximum water-holding capacity in capillary was 90.15 mm in the treatment of irrigation 3 irrigations, and the maximum water-holding capacity in non-capillary was 4.15 mm in treatment of 4 irrigations.

废水灌溉后，土壤pH均值降低6.0%；废水灌溉1～2次，土壤含盐率降低11.7%，废水灌溉3～4次后，增壤含盐率增加12.6%。2）废水灌溉后土壤体积质量均值减小6.5%，总孔隙度均值增大18.1%；随着废水灌溉次数的增多，土壤体积质量和总孔隙度分别有减小和增大的趋势。3）Horton模型比较适合描述废水灌溉后芦苇群落的土壤入渗过程，废水灌溉降低了初渗率，但随着废水灌溉次数的增多，稳渗率增加明显。4）废水灌溉增强了土壤贮蓄水分的能力，废水灌溉3次吸持贮水量达到最高（90.15 mm），灌水4次滞留贮水量达到最高（4.51 mm）。

Zhang asked the teacher's family driver, sent a large 100/car, sending the bridge 80/vehicle; there are going to be great comrades bearing in mind that the attention of ferry time, you can call the ferry, he told us 5:30 also said that, while the Teacher of the house and we say too late, not 4:30, and we want to live in it After dinner under the path along the cliff, no need to please tour guide, the tour guide told you what a tiger jump Stone money to take photographs and the like, but in fact it does not have to go after!

张询问教师的家庭司机，发出了一个大型100/car ，发送的桥梁80/vehicle ；将有很大的同志铭记注意的渡轮时，您可以调用的渡轮，他告诉我们5： 30日也说，虽然教师的房子和我们说为时已晚，而不是4：30 ，我们希望生活在它）晚餐后的路径下沿悬崖，没有必要请导游，导游告诉你什么虎跳石钱拍照等，但实际上它并没有去后！

Water should, however, not be taken immediately after taking coconut water. It may be taken after some time has passed, if necessary.

水应，不过，并非立即采取上台后椰子水，它可能会采取一段时间后已经过去了，如果必要的。

Methods With surgery method treatment collar bone bone fracture 160 examples, in Cleveland needle steel wire fixed 134 examples, reconstructs the steel plate or in the collar bone steel plate the fixed 11 examples, the bolt after the collar bone and the processus coracoideus fixed 12 examples, in the collar bone hook steel plate the fixed 3 examples, after the technique, makes a follow-up visit the review analysis four in fixed methods the adaptation card, the bone fracture cicatrization time and the complication formation rate.

用手术方法治疗锁骨骨折160例，其中克氏针钢丝内固定134例，重建钢板或锁骨钢板内固定11例，螺钉经锁骨与喙突固定12例，锁骨钩钢板内固定3例，术后随访回顾性分析四种内固定方法的适应证、骨折愈合时间及并发症的发生率。

The maxillofacial and brain injuries were examined. Craniptomy was done to animals of impact injury 6 hours after damage, however it was done to animals of explosive injury in different time point (1 hour, 24 hours, 72 hours, 7 days, 14 days after damage). The pathological characteristics of corelative tissues were examined in detail under light and electron microscopes. The content of LPO, SOD, NO in soft tissue, brain, blood, and cerebral water content were measured, compared with control. The distribution and tissue location of NOS were studied by histochemistical and immunohistochemistic methods. Their relationship was studied to assess the pathological and physiological characteristics of maxillofacial injuries and brain damage associated.

撞击伤各组动物于伤后6h、爆炸伤各组动物于伤后不同时期（1h、24h、72h、7d、14d）开颅检查颅脑损伤情况，切取伤区肌组织、左侧脑组织、脑干标本行光镜、电镜观察；测定伤后肌组织、脑组织与血中LPO、SOD、NO含量及脑水含量变化；并使用组织化学和免疫组织化学的方法，观察伤后脑组织中NOS的分布和组织定位，研究伤后机体的病理及病理生理学改变特点，以及颅脑损伤与机体自由基反应、NO含量改变之间的关系，证实其病理作用。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失