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thymus相关的网络例句

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The study of mechanism of its anti-inflammationThis experiment shows that NTL can inhibit the edema of hind paw induced by fresh egg white in adrenalectomized rat, reduce the weight of thymus in rat, increase the content of hepatic glycogen ,but decrease eosinophil of mice through experimentalstudy of effect of NTL on edema of hind paw induced by fresh eggwhite in adrenalectomized rat, weight of thymus in rat, content ofhepatic glycogen and eosinophil of mice. The results indicate that NTL has the analogous function to cortin.

抗炎机理研究通过虎斑游蛇对去肾上腺大鼠蛋清性足跖肿胀、对大鼠胸腺重量和对小鼠肝糖原含量及对小鼠嗜酸性粒细胞数量影响的实验研究,表明虎斑游蛇能够抑制去肾上腺大鼠蛋清性足跖肿胀,使小鼠胸腺的重量减轻,增加小鼠肝糖原的含量而减少嗜酸性粒细胞的数量,提示虎斑游蛇具有肾上腺皮质激素样作用。

The studies on the capacities of immune responses of lymphocytes in peripheral blood and immune organs of Grass Carp (Ctenpharyngoden idellus Cuvier et Valencinnes) to PHA and SPA with incorporation of 〓H-TdR and active reaction of Acid α-Naphthyl Acetate Esterase indicated that there were T and B lymphocytes in peripheral blood of grass carp, but only T lymphocyte and no B lymphocyte in the thymus of grass carp. It was justified that the T lymphocytes in peripheral blood was originated from the thymus, and B lymphocyte could be from the spleen and anterior kidney of grass carp.

运用〓H-TdR掺入法和酸性醋酸萘酯酶活性检测法分别研究了草鱼外周血以及免疫器官中的淋巴细胞对PHA和SPA的免疫应答以及化学标志特征,发现草鱼外周血中存在着类似于哺乳动物的T、B两类不同的淋巴细胞亚群;同时也发现胸腺中只有T淋巴细胞,而无B淋巴细胞,提示了胸腺中淋巴细胞可能是外周血中T细胞的来源,而B淋巴细胞可能来自脾脏或前肾。

The thymus is located on the edge of the gill cover close to the opercular cavity, triangle, is distributed symmetrically. Lobules of thymus are more evident along with increasing age.

观察到鳜胸腺位于鳃盖与背的联合处,呈三角形,对称分布;胸腺实质随年龄增长分叶逐渐明显,大体可分三个区,外区、中区和内区,中区和内区分别相当于哺乳动物的皮质区和髓质区。

Apoptosis of lymphocytes in bone marrow, spleen, thymus and bursa was detected by light microscope, electron microscope and terminal- deoxynucleotidyl transferase UIP nick end labeling. The results showed ALV-J could induce incoordinate apoptosis of lymphocytes in thymus, bursa and spleen, which was mainly found in early time. And the apoptosis was much more obvious in thymus than in other immune organs.

以电镜观察和HE染色、原位末端标记染色光镜观察对ALV-J感染和混合感染鸡的骨髓、脾脏、胸腺、法氏囊等免疫器官中淋巴细胞的凋亡进行了形态学研究,首次发现ALV-J可诱导胸腺、法氏囊和脾脏中不同程度的淋巴细胞凋亡,凋亡主要见于早期,ALV-J与REV混合感染时淋巴细胞凋亡尤为显著,以胸腺中最为明显。

At the first day after injection, 3H-TdR was distributed mostly in spleen, thymus , femur , liver and small intestine according to their activity; 3H-TdR was distributed mostly in blood, kidney, liver, lung, sperma, brain, spleen , small intestine , muscle , thymus and femur in turn on the basis of their absorbed dose.

注后1天,按单位组织的放射性活度计,~3H-TdR主要分布于脾脏、胸腺、股骨、肝脏和小肠;按组织器官的吸收剂量计,依次为外周血、肾脏、肝脏、肺、睾丸、脑、心脏、脾脏、小肠、肌肉、胸腺和股骨。

Among them VLP- 1 100 mg / kg d acts best, the transition rate of achroacyte reach 65.5013%, each VLP -1 dosage has apparent effects to the live weight gain of normal rats' immunization organic, VLP-1 50 mg / kg d and 100 mg / kg d have sorely significantly live weight gain function to thymus and milt, when VLP-1 is 25 mg / kg d, the thymus weight increase sorely significantly while milt increase not too much.

各VLP一1剂量对正常小鼠免疫器官的增重均有明显作用,其中VLP一1在50 mg/kg.d、100 mg/kg·d剂量下对胸腺、脾脏有极显著地增重作用,在25mg/kg 。d 剂量下极显著地增加胸腺重量,而对脾脏增重无影响;粗多糖仅在100mg/kg·d 剂量下对脾脏增重有明显作用外,其余各剂量对正常小鼠胸腺、脾脏增重无影响。

Thymus and autoimmunity: production of CD4+CD25+ naturally anergic and suppressive T cell as a key funtion of the thymus in maintaining immunologic selftolerance.

在人、大鼠和小鼠中有大约3%-10%的CD4+CD8-单阳性胸腺细胞共表达CD25表面分子,这些细胞能够阻止包括自身免疫性胃炎、自身免疫性小肠炎和自身免疫性糖尿病等在内的多种自身免疫性疾病的形成和发展[8-10]。

Compared with control,①the mean tumor weight of H22 of SXKA Granules three dose groups were decreased significantly(P.01,P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 30%;②the mean tumor weight of S180 of SXKA Granules three dose groups were decreased significantly(P.01),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;③the mean tumor weight of EAC of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20 g/kg dose groups were above 38%;④the mean tumor weight of Lewis carcinoma of SXKA Granules three dose groups were decreased significantly(P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10、5 g/kg dose groups were above 36%;⑤the mean tumor weight of W256 of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;⑵Compared with control,SXKA Granules 20、10 g/kg dose groups had extended the survial time of the P388-bearing mice respectively(P.01),and the mean prolong rates of SXKA Granules 20、10 g/kg dose groups were above 50%;⑶Compared with S180-bearing group, SXKA Granules 20、10 g/kg dose groups could increase the weight of thymus and spleen, Spleen index and thymus index were increased, SXKA Granules 5 g/kg dose group could increase thymus index(P.05);⑷As Compared with control group, SXKA Granules 20、10 g/kg dose groups could improve mouse serum half hemolysis value depressed by transplanted tumor dramatically(P.01), which revealed the SXKA granules could improve the mouse humoral immunity system;⑸SXKA Granules 20 g/kg dose group could increase of englobe indexαon S180-bearing mice remarkably(P.01), which indicated the SXKA Granules could improve their cellular immunity system.

对荷W256大鼠,生兴克癌冲剂20、10、5 g / kg三组的平均瘤重明显低于对照组(P.01,P.05),生兴克癌冲剂20、10 g / kg组的平均肿瘤抑制率均大于32 %;⑵与空白对照组相比,生兴克癌冲剂20、10 g/ kg能显著地延长移植小鼠白血病P388小鼠的存活天数(P.01),生兴克癌冲剂20、10 g/ kg对荷白血病P388小鼠生命延长率均在50%以上;⑶与S180荷瘤组相比,生兴克癌冲剂对荷瘤鼠的免疫器官重量、胸腺指数和脾指数有一定的提高趋势,其中生兴克癌冲剂5 g / kg组对荷瘤小鼠的胸腺指数有一定的提高作用(P.05);⑷与S180荷瘤组相比,生兴克癌冲剂20、10 g /kg组可提高由荷瘤引起的小鼠血清半数溶血素值的降低(P.01),表明其可提高荷瘤小鼠体液免疫功能;⑸与对照组相比,生兴克癌冲剂20 g /kg组可提高荷S180肉瘤小鼠的免疫吞噬系数α值(P.01),表明其可提高荷瘤小鼠细胞免疫功能。

The inoculation of MDV in general indued to decrease the production of IL-2、 IFN-γ-Th〓 cytokines in vitro, and there are differences between spleen and Thymus lymphocyte on the production of IL-2 in vitro, only thymus lymphocyte IL-2 prodution increased transient in early time. The cytotoxity TNF induced in thymus and spleen lymphocyte and bone marrow macrophage shown a simillar curve of"V"shape. MDV infection cause cell-mediated immune declines.

MDV接种总体上降低IL-2和IFN-γ-Th〓细胞因子体外诱生,其中IL-2体外诱生在胸腺细胞和脾淋巴细胞有差别,前者有早期短暂增强作用;而对TNF在上述两种细胞和骨髓巨噬细胞的诱生作用呈现类似规律,即呈现&V&形曲线,在接种后早期(1~5天)和25天升高,而在10天开始下降,至第20天降至低谷,MDV感染导致雏鸡细胞免疫水平下降,促进MD发病。

The thymuses, spleens, sera and anticoagulant blood were collected after the rats were killed, to carry out these works:(1) Zinc concentrations were analyzed by atomic absorption spectrophotometry;(2) Body weight and the weight of thymuses and spleens were measured, the organ index were calculated;(3) Changes in pathology of thymus and spleen were observed;(4) Using TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) method, the apoptosis of thmocytes and spleen lymphocytes was checked;(5) The expression of bcl-2、bax mRNA in thymus and spleen were detected by RT-PCR (reverse transcription polymerase chain reaction);(6) The expression of p56〓, a signal transduction protein in thymus and spleen were detected by immunohistochemistry;(7) Two-color cytofluorometric analysis was used to assess the expression of CD4, CD8, CD45RA and CD45RC in peripheral blood lymphocytes.

动物处死后留组织、抗凝血及血清,进行以下检测:(1)原子吸收法测血清锌浓度;(2)测胸腺、脾脏脏器重量并与大鼠体重比较,计算脏器指数;(3)HE染色对胸腺、脾脏进行病理观察;(4)原位末端标记法测胸腺、脾脏中淋巴细胞的自发凋亡,并通过图像分析进行比较;(5)逆转录聚合酶链式反应检测凋亡调控基因bcl-2、bax mRNA在免疫器官中的表达;(6)免疫组化方法检测信号转导蛋白p56〓在免疫器官中的表达;(7)流式细胞术分析外周血淋巴细胞中CD4+、CD8+、CD45RA+及CD45RC+CD4+、CD45RC-CD4+细胞的数量和比例。

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