查询词典 thioridazine

Methods Male Sprague-Dawley rats were injected intraperitoneally with thioridazine of 10 mg·kg-1·d-1 for 2 weeks in order to suppress cognition by inhibition of dopamine, acetylcholine and 5-hydroxytryptamine receptors.

方法20只大鼠随机分为对照组和甲硫哒嗪组，连续2wk分别腹腔注射生理盐水和治疗剂量的甲硫哒嗪(10mg·kg-1)。

The fluorescence intensity measured was linear proportional with the concentration of free thioridazine hydrochloride in mixed solution over the range from 1×10-5 to 2×10-4 mol/L with the detection limit of 6×10-6 mol/L.

利用流动注射在线氧化结合在线透析采样技术建立了荧光法测定血浆中游离盐酸硫利达嗪的新方法，并将其应用于盐酸硫利达嗪与牛血清白蛋白作用机制的研究。

Thioridazine ; cognitive function ;β-amyloid ;β-amyloid precursor protein ; Alzheimers disease

甲硫哒嗪；认知功能；β-淀粉样蛋白；β-淀粉样前体蛋白；阿尔采末病

And we also proposed new methods to the study of thioridazine hydrochloride-BSA binding and methotrexate in dissolution testing based on dialysis sampling and flow injection on-line filtration, dilution techniques.

将方法应用于片剂中盐酸硫利达嗪含量的分析，测定结果与药典法一致。结果表明该方法具有检出限低、线性范围宽、精密度好以及分析速度快等特点。

In this thesis, we used this principle coupled with flow injection solid phase reactor on-line oxidation, solid phase extract and dialysis separation technology to establish the on-line oxidizing fluorometric method for determination thioridazine hydrochloride and methotrexate in table and plasma samples, respectively.

第二章：研究报告一、流动注射在线氧化荧光法盐酸硫利达嗪分析体系研究流动注射在线氧化荧光法测定药物中盐酸硫利达嗪含量本方法根据盐酸硫利达嗪的氧化产物具有强荧光这一性质，在磷酸介质中利用二氧化铅固相反应器在线氧化盐酸硫利达嗪并通过乙醇对其的增敏作用，建立了流动注射在线氧化荧光法测定盐酸硫利达嗪含量的新方法。

According to the fluorescence measurement results from mixed solution, the association constant estimated for thioridazine hydrochloride-BSA binding and the number of the binding site with Scatchard analysis were 1.2×104 L/mol and 0.98, respectively.

将盐酸硫利达嗪与牛血清白蛋白以不同比例混合并在37 ℃下培养，以流动注射透析采样技术从混合液中分离出游离盐酸硫利达嗪，在线氧化为强荧光化合物后测定其浓度；应用Scrathard方程分析所测数据，求得盐酸硫利达嗪和牛血清白蛋白的结合常数为1.2×104 L/mol，结合位点数为0.98；根据热力学参数推断，盐酸硫利达嗪与牛血清白蛋白之间以疏水作用力为主；进一步基于荧光猝灭现象和Fster非辐射能量转移理论，得到盐酸硫利达嗪小分子与牛血清白蛋白之间的能量转移效率( E =0.497)和结合距离( r 0=3.27 nm)。

The man, who also had polysubstance dependence and dementia secondary to lead poisoning , had been treated with chlorpromazine, thioridazine, loxapine and haloperidol.

1例男性患者使用氯丙嗪、甲硫达嗪、洛沙平和氟派啶醇治疗，发生多重药物依赖，并导致中毒。

MATERIALS AND METHODS: Using Clinical Laboratory Standard Institute method, antifungal activity of fluconazole was determined alone and in combination with 16 chemosensitizers that included verapamil, reserpine, quinine, quinidine, gemfibrozil, lansoprazole, tamoxifen, diltiazem, desipramine, nicardipine, cyclosporine, chlorpromazine, prochlorperazine, promethazine, thioridazine, and trifluoperazine.

材料与方法：采用临床实验室标准制定的方法，氟康唑抗真菌活性的测定分为单独用氟康唑和氟康唑结合异博定、利血平、喹宁、喹纳定、吉非罗奇、地尔硫卓……等的测定。

Hanna: That's over now, isn't it?

都结束了，对吗

You must be ill. You look so pale.

你一定是病了，你的脸色苍白。