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It is typically used to treat liver cirrhosis, chronic hepatitis, toxin-induced liver damage including the prevention of severe liver damage from Amanita phalloides (death cap mushroom poisoning, and gallbladder disorders.

它通常用于治疗肝硬化,慢性肝炎,毒素诱导的肝,包括从毒鹅膏蘑菇中毒),胆囊疾病和严重肝损害的预防损害。

Results The change on morphous,size,liver lobe proportion,parenchyma density and portal vein in decompensation phase of liver cirrhosis was often observed,while splenectasis,collateral circulation construction,abnormality perfuse,ascitic fluid and pleural fluid also found in spiral CT scanning of liver cirrhosis.

结果 肝硬化在失代偿期CT表现有明显异常,肝脏有不同程度的形态、大小及肝叶比例改变,肝脏表面的实质密度、门静脉也有改变,并且常伴有侧支循环的建立、肝脏异常灌注、脾增大、胸腹水等。

ALT, AST, serum albumin, globulin in serum and SOD, MDA in liver and liver histological changes were measured to confirm the ability of protecting liver of Danxiongfang.

结果:丹芎方和各组分均可抑制CCl4损伤后血浆中ALT和AST的异常增高,提高血清和肝脏中SOD活性,减少MDA形成,升高血浆中总蛋白、白蛋白水平,减轻肝脏疏松化及脂肪变性。

Liver tissue inflammation and collagen deposition were observed with HE staining and sirus red staining;Liver function,Liver tissue hydroxyproline content were determined biochemically.Results:Compared to that of normal rats,The serum ALT、AST activity of model group elevates significantly,Alb and TP lower markedly.

观察模型大鼠体重、肝脾体重等变化,HE染色及天狼猩红染色观察肝组织炎症与胶原沉积病理改变,检测血清肝功能及肝组织羟脯氨酸(Hydroxyproline,Hyp)含量。

Results compared with model control group,dongbao gantai group, the level of body weight,liver index, tc ,tg, alt,ast in serum in tiaozhi hugan decoction group were lower significantly .the level of hld-c was higher.,the level of mda in tiaozhi hugan decoction was lower significantly, the level of sod was higher significantly(in all group p<0.01)conclusion it suggests that the pharmacodynamics mechanisms of tiaozhi hugan decoction to fatty liver induced by high fatty diet are lowering body weight and liver index, adjusting lipometabolism, improving liver function and having anti-lipid peroxidation effects.

结果 与病理模型组、东宝甘泰组比较调脂护肝方组大鼠体重、肝指数血清tc值、tg值均降低,hld-c值增高,血清alt、ast、mda值均较低,sod值较高(各组比较p.01)。结论调脂护肝方干预非酒精性脂肪肝的药效机制为:降低体重与肝指数,调整脂质代谢,改善肝功能,抗脂质过氧化。

The elimination half-life t(subscript β1/2 was 161.10h, 333.21 h and 611.26h, respectively, and the total body clearance was 27.4mL/, 16.8g/ and 18.0g/, respectively. The metabolite ciprofloxacin concentration-time profiles of the plasma, muscle and liver presented similar trend. The multi- peak phenomenon were observed in the plasma, muscle and liver, but the first peak time was 24h, 24h and 12h, respectively. The peak residue of metabolite ciprofloxacin was in liver, muscle and plasma, ordinally. The eliminating rate of ciprofloxacin from muscle and liver was very low.

代谢物环丙沙星在鳗鲡血浆、肌肉和肝脏中药物水平的变化趋势与恩诺沙星基本相似,呈现出多峰现象,但3种组织中环丙沙星出现第一个药峰时间分别为给药后第24小时、24小时和12小时,3种组织中环丙沙星峰值水平肝脏中最高、肌肉中次之、血浆中最低,环丙沙星在肌肉和肝脏中的消除速率比较缓慢。

The faciform ligament is an important sign of laparoscopic liver surgery and a way of collateral circulation of liver. The superior liver artery found and named in this research can be an important sign to judge the position of hepatic vein. The operation pathway by cutting down the perihepatic ligament next to the superior border of liver is a quick way with little blood. It is difficult to hurt diaphragm and hepatic vein, and the secundum porta hepatic can be showed clearly. As a rule, we break the hepatic vein in the hepatic parenchyma on laparoscopic hepatectomy. But in some situation, extrahepatic treatment was used.

镰状韧带是腹腔镜肝脏外科入路的重要标志,是肝脏侧枝循环的重要途径;本文所发现并命名的肝上动脉可以作为判定肝静脉位置的重要标志;紧贴肝上缘打开肝周韧带,不易损伤膈肌和肝静脉,出血少、速度快,可以使第二肝门获得良好的手术显露;腹腔镜肝切除时一般在肝实质内切断肝静脉,在个别情况也可以预先在第二肝门结扎切断肝静脉。

This experimental study, based on the ischemia-reperfusion injury model of the isolated rabbit liver, was to investigate hepatocellular apoptosis and its mechanism during cold preservation-reperfusion of donor liver and assess the structural and functional damages of the reperfusing donor liver subsequent to rewarm ischemia. In addition, the expression and effects of ICAM-1 mRNA were mainly observed during rewarm ischemia-reperfusion of donor livers. Our experiment included three parts: The first was establishment of the isolated liver ischemia-reperfusion injury model in rabbits.

本实验在建立离体供肝缺血-再灌注损伤模型的基础上,研究供肝低温保存-再灌注过程中肝细胞凋亡现象及其相关机制;探讨作为临床肝移植中供肝的另一缺血阶段—复温缺血对再灌注后供肝结构及功能的损伤作用,并着重观察供肝复温缺血-再灌注期间组织细胞内细胞间粘附分子-1 mRNA的表达规律及其作用。

Methods Liver function Child A level group were 15 examples,liver function Child B level group were 20 examples,liver function Child C level group were 25 examples,CT surveyed 3 groups of portal veins,the stomach coronary vein diameter,the fundus ventriculi - spleen gate area in vein blood vessel section of total area,carried on the analysis with the clinical liver cirrhosis Child graduation.

肝功能Child A级组15例,肝功能Child B级组20例,肝功能Child C级组25例,CT测量3组的门静脉、胃冠状静脉直径,胃底-脾门区静脉血管截面总面积,与临床肝硬化Child分级进行分析。

Result 3.1 Ultrasound result We amended the criterrion little which Hitachicommpany offered. According as the criterion, it is 1 score if liver tissues have notdifference of elasticity and there are green in the region of interest. It is 2 score ifliver tissues have not significance difference of elasticity and there are blue in greenin the region of interest. It is 3 score if liver tissues have difference of elasticity andthere are green in the region of interest of normal liver tissues and blue in the region of interest of abnormal liver tissues. After examination, we anatomised rats and gotliver tissues for pathologic checkout.

结果 3.1超声检查情况根据日立公司提供的评分标准,稍做修改,将肝组织弹性无差异,取样框内颜色均为绿色,评为1分;肝组织弹性无明显差异,取样框中颜色为绿色中微微带点蓝色,评为2分;肝组织弹性有差异,取样框内正常肝组织弹性变化为绿色,病变肝组织弹性变化为蓝色,评为3分。

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