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Excessive aggradation of extracellular matrix in the liver is the pathologic characteristic of hepatic fibrosis.The development of liver fibrosis is a dynamical process which is mainly due to the activation of the hepatic stellate cells, including not only excessive synthesis of ECM, but also its deficient degradation.

肝纤维化以细胞外基质在肝脏弥漫性过度沉积为病理特征,其形成主要由于肝星状细胞活化,ECM过度生成,降解相对不足,在肝内大量沉积所致。

In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响,结果表明SY-801和SY-640体内连续给药3天,可诱导小鼠肝微粒体细胞色素P-450含量明显增加,同时氨基比林脱甲基酶活性亦明显增加;给药1次2小时内二者均可抑制氨基比林脱甲基酶活性,而对肝微粒体细胞色素P-450含量则无明显影响。

The aims of this study were:(1) to find methods to analyze 7-tocopherol and its metabolites;(2) to study the kinetics of 7-tocopherol metabolized in the S9 of male SD-rat liver in vitro;(3) to compare the differences of 7-tocopherol metabolized in the liver S9 of male SD-rat, male Brazil turtle and male cobia, respectively.

研究内容主要是:(1)γ-生育酚代谢物的分析方法;(2)γ-生育酚在雄性SD-大鼠肝S9的体外代谢动力学;(3)比较γ-生育酚在不同代谢水平动物的肝S9中代谢的差异。

METHODS: Total 60 male Wistar rats were randomly divided into 6 groups, i.e., normal control group , DMN model group , large dose treatment group , middle dose treatment group, small dose treatment group and Dongbao gantai treatment group. The liver fibrotic model was induced by i.p. dimethylnitrosamine for 4wk. The relative herbs were given after model establishment in each treatment group and the administration lasted for 6 weeks. Decollate to get the blood and The serum hepatofibrosis indexes, hyaluronic acid, collagen IV, pro-collagen type III and laminin were measuredwith radioimmunoassay. SOD and MDA were measured with biochemistry method. The liver pathological changes were observed in each group of rats.

将60只雄性Wistar大鼠随即机分正常对照组、模型对照组、实验大剂量组(20ml/kg/d)、实验中剂量组(10ml/kg/d)、实验小剂量组(5ml/kg/d)及东宝肝泰药物对照组;腹腔注射二甲基亚硝胺制备大鼠肝纤维化模型,连续灌胃6周,断头取血,生化检测血清SOD、MDA;放射免疫法测定血清HA、LN、PCIII及IV-C;取肝左叶做HE染色和Mallory胶原染色,观察肝病理组织学改变。

Furthermore, the liver could get the second hit by mechanical, immuneological, bio-barrier demolishment and endocrine function inbalance of the small bowel, which results in the liver function deteriorated.

肠道是应激反应的中心器官,由于肠道机械、免疫、内分泌、生物屏障的破坏等因素,肝脏受到"二次打击"的序惯性损伤。

At the same time of the fat denaturalization ,the liver lipid , blood lipid and the liver function enzymes increased .

肝脏细胞发生脂肪变性的同时肝脏脂质、血脂和肝功能酶类升高,血脂与肝脂的变化呈正相关,肝功能酶类变化也呈正相关。

Modeling in the 1~3 weeks-the liver department district expanded proliferative fibrosis, fatty degeneration of liver cells.

建模第1~3周,肝脏的汇管区扩大,出现纤维性增生,肝细胞发生脂肪变性。

DMSA is stressful to the liver. ALA is helpful to the liver.

DMSA 会对肝产生影响的而 ALA 对肝是有益的。

Methods Physiological and biochemical parameters of the blood were determined to detect liver function. Membrane protein and nuclear protein were isolated from the liver tissue of BDL rats.

胆总管结扎术法制备大鼠梗阻性黄疸模型,检测肝功能;提取大鼠肝细胞膜蛋白与核蛋白,测定提取液蛋白浓度;采用Western blot技术检测MRP3和Lrh-1蛋白表达。

Methods Physiological and biochemical parameters of the blood were determined to detect liver function. membrane protein and nuclear protein were isolated from the liver tissue of BDL rats. The protein expressions of MRP2 and FXR were determined by Western blot.

用胆总管结扎术方法制备大鼠梗阻性黄疸模型,检测肝功能;提取大鼠肝细胞膜蛋白与核蛋白,测定提取液蛋白浓度;采用Western blot技术检测MRP2和FXR蛋白表达。

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相关中文对照歌词
Take Me To The Liver
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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?