the 1

Now my courtyard in January 2006, the cataract of gimmick small cut that undertook in January 2008 excises combination artificial crystalline lens appears to low eyesight patient has case study and be adopted after embedded operation nurse accordingly, obtain favorable result, report as follows now. 1 clinical data 1.1 average data in January 2006, the operation treated a patient in January 2008 562 (594), male 304, female 290; age 6 years old of ~89 year old, senile sex cataract 482 (504), traumatic sex cataract 26 (26), complication cataract 50 (60), congenital cataract 4 (4), light of the eyesight before art feels - 0.3, there is the person that force of backsight of art of apparent diagnostic effect restores 26 times before art, among them diabetic retinal pathological changes 10, pathological changes of senile sex yellow spot 8, glaucoma optic nerve is damaged 7 times, corneal blaze 1. Standard of 1.2 low eyesight diagnoses watch of eyesight of standard of standard application international to undertake checking according to our country low eyesight, optimal and correctional eyesight is in 3 months after art 0.05 above, but in 0.3 it is low eyesight standard below. 1.3 results 594 art hind are inchoate...

现将我院2006年1月—2008年1月进行的手法小切口白内障摘除联合人工晶状体植入手术后出现低视力病人进行原因分析并采取相应护理，取得良好效果，现报告如下。1临床资料1.1一般资料2006年1月—2008年1月手术治疗病人562例(594眼)，男304眼，女290眼；年龄6岁~89岁，老年性白内障482例(504眼)，外伤性白内障26例(26眼)，并发症白内障50例(60眼)，先天性白内障4例(4眼)，术前视力光感-0.3，术前有明显诊断影响术后视力恢复者26眼，其中糖尿病视网膜病变10眼，老年性黄斑病变8眼，青光眼视神经损害7眼，角膜白斑1眼。1.2低视力标准根据我国低视力诊断标准应用国际标准视力表进行检查，术后3个月最佳矫正视力在0.05以上，但在0.3以下为低视力标准。1.3结果594眼术后早期。。。

METHODS:The 12～14 months old rats which sexual circle being disorder were chosed;the groups were Yanfuchun 5.0 g.kg-1,Yanfuchun 10 g.kg-1,Gengnianan 1.1 g.kg-1,model group and young controls;the rats were administered in continuousness orally Yanfuchun 5.0,10.0 g.kg-1,Gengnianan 1.1 g.kg-1 and the same volume of water for 22 days respectively.

选用12～14月龄动情周期紊乱的雌性大鼠进行实验，实验分延妇春5.0、10 g.kg-1；更年安1.1 g.kg－1，模型组及青年对照组；分别给大鼠连续灌胃延妇春5.0 g.kg－1。延妇春10 g.kg－1；更年安1.1 g.kg－1及等量蒸馏水22天。

Two ferrocenyl and trimethylsilyl substituted cyanohydrin ethers have been prepared by the addition of trimethysilyl cyanide to two acetyl-substituted ferrocenes: 1-(1-cyano-1-trimethylsilyloxyethyl)-ferrocene (1) and 1, 1'-bis(l-cyano-1-trimethylsilyloxyethyl)ferrocene (2). The structures of these two compounds were characterized by elemental analysis, IR, 1H NMR and X-ray crystallography.

通过两种取代的乙酰基二茂铁与三甲基氰硅烷的加成反应，得到两种取代二茂铁基三甲基硅烷基氰醇醚的晶体：1-（1-氰基－1-三甲基硅烷氧基乙烷基）二茂铁(1)，1，1-二（1-氰基－1-三甲基硅烷氧基乙烷基）二茂铁(2)，用X射线单晶衍射、元素分析、红外光谱和核磁共振氢谱对分子结构进行了表征。

Types of the combination were as follows: ASD and VSD, 2 cases; ASD and PS, 2 cases; ASD and MS, 1 case; ASD and coronary artery stenosis, which needed interventional treatment, 1 case; VSD and PDA, 3 cases; ASD and anomalous inferior vein cava drainage, 1 case; PDA and B-preexcitation syndrome, 1 case; PDA and dextrocardia, anomalous inferior vein cava drainage, 1 case.

复合类型为：房间隔缺损合并室间隔缺损2例，ASD合并肺动脉瓣狭窄2例，ASD合并二尖瓣狭窄1例，ASD合并冠脉狭窄需介入治疗1例，ASD合并右位心1例，VSD合并动脉导管未闭3例，PDA合并B型预激综合征1例，PDA右位心、下腔静脉肝段缺如1例，VSD合并下腔静脉肝段缺如1例。

In this paper,the Raman spectrum were used to study sapphire,dichroite,aquamarinl,topaz and kyanite,it is found that the characteristic Raman translocations of sapphire which are caused by Al-O vibration are 413cm-1,640cm-1 and 668cm-1,the characteristic Raman translocations of dichroite which are caused by Si-O vibration are 550cm-1,662cm-1,964cm-1and 1176cm-1,the characteris.

本文通过对蓝宝石、堇青石、蓝色托帕石、海蓝宝石和蓝晶石的拉曼光谱进行测试与研究，得到蓝宝石具有由Al-O振动引起的特征拉曼位移413cm-1，640cm-1和668cm-1；堇青石具有由Si-O振动引起的特征拉曼位移550cm-1，662cm-1，964cm-1和1176cm-1；海蓝宝石具有由Si-O振动引起的特征拉曼位移678cm-1，1064cm-1，1232cm-1；蓝色托帕石具有由Si-O振动引起的特征拉曼位移844cm-1和924cm-1；蓝晶石具有由Si-O引起的特征拉曼位移933cm-1和1133cm-1。

Results:①The doses of 0.8 g·kg-1, 1.2 g·kg-1, 1.6g·kg-1 and 2.0g·kg-1 of AMJ could delay the time of fatigue in nerve centre, neuromuscular junction and muscle of mice, but in hoptoad, only the doses of 0.8 g·kg-1 and 1.2g·kg-1 have the same effect,the dose of 1.6g·kg-1 and larger doses could accelerate the fatigue.

结果：① 0.8g·kg-1、1.2g·kg-1、1.6g·kg-1和2.0g·kg-1剂量的黄芪注射液均能延缓小鼠中枢、神经-肌接头和肌的疲劳，蟾蜍仅有0.8 g·kg-1和1.2 g·kg-1有此作用，1.6g·kg-1及以上剂量的黄芪注射液对蟾蜍有加速上述部位疲劳的作用。

This invention provides compounds of Formula; wherein: R is a moiety selected from the group: and n is an integer of 1 or 2; R is selected from hydrogen, amino,-NRR, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, alkynyl of 2 to 12 carbon atoms optionally substituted, halogen, and a 5 to 10 membered heteroaryl ring optionally substituted, having 1 to 4 heteroatoms independently selected from N, O and S; R is selected from hydrogen, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, vinyl, alkynyl of 2 to 12 carbon atoms optionally substituted and halogen; R is H, alkyl of 1 to 12 carbon atoms optionally substituted, cycloalkyl of 3 to 8 carbon atoms, bicycloalkyl of 5 to 10 carbon atoms or aralkyl optionally substituted; R is OH or -OH; R and R are each independently H or alkyl of 1 to 12 carbon atoms or when optionally taken together with the nitrogen atom to which each is attached form a 3 to 8 membered saturated heterocyclyl ring; R is alkyl of 1 to 12 carbon atoms optionally substituted; or a tautomer or pharmaceutically acceptable salts thereof.

本发明提供式的化合物；其中：R 1 为选自基团和的部分；n为整数1或2；R 2 选自氢、氨基、-NR 6 R 7 、具有1到12个碳原子的视情况经取代的烷基、具有6个、10个或14个碳原子的视情况经取代的芳基、具有2到12个碳原子的视情况经取代的烯基、具有2到12个碳原子的视情况经取代的炔基、卤素和具有1到4个独立地选自N、O和S的杂原子的视情况经取代的5元到10元杂芳基环；R 3 选自氢、具有1到12个碳原子的视情况经取代的烷基、具有6个、10个或14个碳原子的视情况经取代的芳基、具有2到12个碳原子的视情况经取代的烯基、乙烯基、具有2到12个碳原子的视情况经取代的炔基和卤素；R 4 为H、具有1到12个碳原子的视情况经取代的烷基、具有3到8个碳原子的环烷基、具有5到10个碳原子的双环烷基或视情况经取代的芳烷基；R 5 为OH或-OH 8 ；R 6 和R 7 各自独立地为H或具有1到12个碳原子的烷基，或当视情况与其所连接的氮原子连接在一起时形成3元到8元饱和杂环基环；R 8 为具有1到12个碳原子的视情况经取代的烷基；或其互变异构体或医药学上可接受的盐。

METHODS: A randomized comparative study was carried out for 28 patients of quetiapine group which were treated with quetiapine (130±s 60)mgd^(-1), 25-400mgd^(-1), individually; and 23 patients of haloperidol group receivid haloperidol (4.8±1.4)mgd^(-1), 2-20mgd^(-1), individually; with a course of 12 wk. BEHAVE-AD was used for the pathogenesis analysis of denmentia before and after treatment.

采用随机对照研究，喹硫平组28例，剂量(130±60)mgd^(-1)， 25~400mgd^(-1)，氟哌唆醇组23例，剂量(4.8±1.4)mgd^(-1)， 2~20mgd^(-1)，疗程12wk，治疗前后采用痴呆病理分析评定量表和治疗时出现的症状量表评定疗效和不良反应。

A brief review of preparation of three 1,1'binaphthyls with nonidentical groups in 2, 2'positions: 2amino2'hydroxy1,1'binaphthyl, 2hydroxy2'mercapto1,1'binaphthyl and 2amino2' mercapto1,1'binaphthyl was prespented, and the progress on their application in the asymmetrical synthesis was outlined.

概述了 2 ，2'位置上带有不同取代基的 1，1'联萘化合物，如 2氨基 2'羟基 1，1'联萘、2羟基 2'巯基 1，1'联萘和 2氨基 2'巯基 1，1'联萘的制备及在不对称合成中的应用研究进展。

AIM To investigate the effect of methyl pentyl 1,4 dihydro 2,6 dimethyl 4 (3 nitrophenyl) 3,5 pyridinedicarboxylate (MN9202),a dihydropyridine calcium antagonist, on cardiac indexes,ultrastructure, superoxide dismatase,glutathione peroxidase activity and malondialdehyde concentration in cardiac hypertrophy induced by L thyroxine in rats.

连续 12 d ip L- Thy0 。5 mg·kg- 1 · d- 1 复制大鼠心肌肥厚模型，实验组 ip MN92 0 2 0 。4mg· kg- 1· d- 1 ，2 mg·kg- 1· d- 1 ，10 mg· kg- 1· d- 1 ，阳性对照组 ip卡托普利 2 5 mg· kg- 1 · d- 1 ，模型组、对照组给予等量溶剂，于给药后的第 13日处死大鼠，检测心脏指数，电镜观察心肌组织的超微结构变化，化学比色法测定心肌匀浆中 SOD、GSH- PX活性和 MDA含量。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。