查询词典 tetanus toxin

Several antigens of pathogenic microorganisms, such as C subunit of tetanus toxin and the Brucella abortus ribosomal protein L7/L12, were successfully expressed in Lactococcus lactis.

破伤风毒素片段C、布氏杆菌L7／L12蛋白等多种病原微生物抗原已成功在乳酸乳球菌中表达，并已证明部分重组乳酸乳球菌作为黏膜免疫疫苗可以同时刺激局部黏膜免疫应答和系统免疫应答。

Objective To analyze the immunogenicity of tetanus toxin fragment C expressed in E.

目的 分析大肠杆菌表达的破伤风毒素C片段的免疫原性。

Objective To obtain highly purified tetanus toxin fragment C with good immunogenicity.

目的获得高纯度、高免疫原性的破伤风毒素C片段蛋白。

Methods Express tetanus toxin fragment C in E.

均获得高纯度的破伤风毒素。

Purification of tetanus toxin was carried out by chromatography procedures.

用疏水层析和离子交换层析纯化破伤风毒素。

Will control the synthesis of tetanus toxin gene implanted in mice nerve cells, by regulating the toxin activity, the development of free mice brain circuit switching technology.

将控制破伤风毒素合成的基因植入实验鼠神经细胞，通过调节毒素活动，开发出可自由开关实验鼠脑神经回路的技术。

DNA vaccines with sin2 gle2chain Fv fused to fragment C of tetanus toxin induce protectiveimmunity against lymphoma and myeloma.

蛋白疫苗实验表明，在BCL1 小鼠模型中蛋白疫苗诱导出的抗独特型抗体主要作用在免疫球蛋白重链可变区 [13 ] 。

The invention provides a human McAb to tetanus toxin, being a human antibody, which consists of an antibody variable region and an antibody constant region or not, having the ability of neutralizing the tetanus toxin, with the variable region gene and protein sequence indicated as the sequence table 1. The invention is characterized in that the antibody can not induce obvious allergic reaction, has higher titer and longer effect without any animal virus pollution, and can be produced in an unlimited quantity, which also provides the relating biological functions, the testing methods, the manufacturing method and the application.

A 本发明提供一种人源抗破伤风毒素单克隆抗体，其为人源抗体，包括抗体可变区，该抗体包括或不包括抗体的恒定区，该抗体具有中和破伤风毒素的能力，抗体可变区的基因和蛋白质序列如序列表1所示；其具有不会诱发明显的过敏反应，有较高的效价且长效，产品无动物病毒污染，可以无限量地生产；本发明还提供了其生物功能、测定方法、生产制造方法及其应用。

Interference with presynaptic vesicle fusion by exposure to tetanus toxin reverted functional to silent transmission, implicating SNARE-mediated fusion as a determinant of the ratio of NMDA:AMPA receptor activation.

以破伤风毒素干扰前突触链胞分泌，影响了无讯号传导，并显示以SNARE造成的分泌，决定NMDA受体与AMPA受体的激发的比率。

Now, research replaces the option of index in the various disease appraisement of curative effect to discuss , if with blood plasma 羟 hydrogen can appraise when ketone density is replacing index A flat kind ease pain medicine Kong Shi dose relieve pain effect , is taking ATT( aim at the antibody effect of tetanus toxin) as replacing index to appraise the immunity inhibition researchs of? single clone antibody 5c 8 of the CD 154 in monkey body to get better effect.

目前，已有研究就多种疾病疗效评价中替代指标的选择进行了探讨，如以血浆羟氢可待酮浓度作为替代指标评价阿片类镇痛药控释剂的止痛效果、以 ATT(针对破伤风毒素的抗体效应)作为替代指标评价猴体内 CD154的单克隆抗体5c 8的免疫抑制作用等研究都取得了较好的效果。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。