查询词典 targeted

In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文题名反义与反基因寡核苷酸及其萘二酰亚胺偶联物对靶基因表达的抑制作用研究副题名外文题名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 论文作者李军生导师张元兴魏东芝教授学科专业生物化工研究领域\研究方向生物化学与分子生物学学位级别博士学位授予单位华东理工大学学位授予日期2001 论文页码总数106页关键词基因表达基因治疗反义寡核苷酸反基因寡核苷酸核酸馆藏号BSLW /2001 /Q78 /264 针对人表皮癌抗阿霉素细胞株（KB-A-1）的多药抗药性问题，本文从反义核酸和反基因核酸角度，通过MTT法检测细胞生长情况，ELISA法检测基因表达产物P-gp表达水平的变化，对寡核苷酸抑制肿瘤细胞MDR1基因表达的机制进行了探讨。

Methods and Results— We generated a gene-targeted mouse in which the active CathA was replaced with a mutant enzyme carrying a Ser190Ala substitution in the active site.

方法和结果——我们用在活性部位Ser190Ala替代的突变酶取代有活性的CathA，培养了基因定向小鼠。

The resulting CEbus standard, which the industry adopted in 1994 as EIA-600, targeted remote control, remote instrumentation, security systems, energy management, and entertainment coordination with other wiring that carried the entertainment content.

也正是因为噪音，电力线网络技术或者限制信号带宽，比如X10、SmartLab以及通用电力总线等标准和组织所做的尝试，或者采用复杂昂贵的噪音和误差消除技术，比如HomePlug AV标准，这些方案带来的后果就是没法大范围推广。

These pistols targeted for civilian markets where ownership of the firearms chambered in "military" calibers is prohibited, or for those shooters who can't withstand more severe recoil of the "bigger" calibers.

民用市场的发展目标，这些手枪那里的枪支所有权腔的&军事&口径的禁止，或对那些射手谁不能承受更严重的&大反冲力&口径。

METHODS: Patients were randomised in a 1:1 ratio to undergo screening colonoscopy using either chromoscopic endomicroscopy or chromoscopy alone with targeted biopsies.

比较2组检出在上皮内瘤样病变和结肠癌的诊断阳性率上的差异。研究方法：患者随机按1：1的比例分配到结肠镜组和显微内镜组。

Endomicroscopy targeted biopsies increased the diagnostic yield of intraepithelial neoplasia as compared to chromoscopy guided biopsies alone by 2.5-fold.

对上皮内瘤样病变的诊断阳性率，显微内镜辅助下靶向活检是普通结肠镜辅助下活检的2.5倍。

Previous studies have compared the diagnostic yield of endomicroscopy with conventional "white light" endoscopy and hence the overall objective increase of endomicroscopy targeted biopsies as compared to chromoscopy guided alone is not apparent.

以往的研究比较了传统的光学内镜和和显微内镜在诊断阳性率上的差异。因此，较之结肠镜辅助下的染色检查，越来越多的人选用在显微内镜辅助下行靶向活检。

Methods: Retrospective analysis of 1 073 cases since 2004 from the routine of the radical surgery of lung cancer patients,in a targeted operation to take preventive measures,as well as the treatment with the chylothorax after the operation.

回顾性分析自2004年起1 073例行肺癌根治性手术的病人，术中采取有针对性的预防措施，以及术后并发乳糜胸的治疗方法。

Methods RNAi combinant adenovirus vector which targeted 1566 site of NF-κB p65 mRNA was constructed and the effect of p65 gene knockdown in HUVEC was detected by Western blot analysis.

构建针对NF-κBp65 mRNA序列1566位点的重组RNAi腺病毒表达载体，并利用RNAi腺病毒抑制HUVEC p65表达。

Methods: Our Hospital in January 2003 to 2007 a menstrual tubal lipiodol angiography for the diagnosis and laparoscopic bilateral proximal tubal blockage, Ms tubal patency part of the 31 patients targeted to tubal cornual implantation.

我院2003 年1月至2007年1月经输卵管碘油造影及腹腔镜诊断为双侧输卵管近端堵塞，余输卵管部位通畅的31例患者为对象，行输卵管宫角植入术。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。