查询词典 systemic-toxic

Abstract］ objective for the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.methods aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with ph 4, human immunoglobulin and human hepatitis b immunoglobulin for intravenous injection with ph 4/pasteurization,treatment on human fibrinogen and human coagulation factor ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.the mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.results human albumin pasteurization inactivated vsv and sindbis virus,hrig low ph inactivated vsv and sindbis virus,hrig low ph inactivated hiv virus,ivig low ph/pasteurization inactivated hiv virus,ivig low ph inactivated hiv virus,hbig low ph/pasteurization inactivated vsv,sindbis and polio virus.conclusion suggestion about improvement on unreasonable parameter and standard of virus inactivation is made,cultivate target virus directly from final product by appropriate cell or method to monitoring viral safety of blood plasma product is advanced.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参数。方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低ph常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低ph/巴氏消毒法；人纤维蛋白原、人凝血因子ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。结果人血白蛋白巴氏灭活vsv与sindbis病毒，hrig低ph灭活vsv和sindbis病毒，hrig低ph灭活hiv病毒，ivig低ph/巴氏灭活hiv病毒，ivig低ph灭活hiv病毒，hbig低ph/巴氏灭活vsv、sindbis与polio病毒。结论建议改进病毒灭活验证标准与不合理的灭活参数；采用终产品样品通过合适细胞或方法直接培养目标病毒来有效监测血液制品的病毒安全性。

Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.The mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.

系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低pH常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低pH/巴氏消毒法；人纤维蛋白原、人凝血因子Ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。

Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.

系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病(本论文仅供参考，如需转载本文，请务必注明原作者以及转载来源：论文图书馆 www.lwlib.com)作者：魏宪义，魏红，蹇远勇，陈海，刘文芳目的分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参数。

Results A closure of the mitral and tricuspid valves with simultaneous opening of the aortic valve occurred exclusively during chest compression, resulting in forward blood flow in the pulmonary and systemic circulation. Peak forward aortic flow at a velocity of 58.8±11.6?cm/s was recorded during the compression phase.

结果 所有的6例病人，胸按压时，二尖瓣和三尖瓣关闭，同时主动脉瓣开放，前向血流自心室进入体循环和肺循环；发生在胸按压时的主动脉瓣峰值前向血流速度为58.8±11.6？

Systemic numerical tests are implemented to analyze the dynamic response of the pre-stressed anchorages with different rock damping under different blasting condition and the dynamic stress behaviors on the response of single anchorage and group anchorages are obtained, then a safety measures and guideline are suggested for design and construction.

4针对不同岩体阻尼条件与布设距离不同爆破荷载条件下预应力锚索的动态响应规律进行了系统的数值试验研究，得到了岩质高边坡预应力群锚的爆破动应力变化规律，提出了安全预应力锚索在爆破条件下的安全施工措施与指标。

A recent letter sent to Treasury Secretary Henry Paulson, and signed by a dozen real-estate trade groups, painted a bleak scenario:'Right now, we believe there is insufficient systemic capacity to refinance expiring, performing commercial real-estate loans,' said the letter.

10多家地产交易机构近期向美国财政部长鲍尔森联名致函，描述了一幅惨淡图景：他们在信上表示，我们认为现在的信贷体系能力不足于为即将到期的良好商业地产贷款提供再融资。

Therefore, there have the important practicatol of city transportation plan in our country, but metropolis circle rail transit plan research then just started, although has carried on the Yangtze River delta area rail transit plan, the Zhujiang Delta rail transit plan, also has yielded many results, but still has not formed the systemic theory and method.

我国在城市交通规划及城市轨道交通规划研究中已经积累了丰富的理论与方法，但是对于都市圈交通规划研究则刚刚起步，虽然我国也进行了长江三角洲地区轨道交通规划、珠江三角洲轨道交通规划，也取得了不少成果，但仍然没有形成系统的理论与方法。

The development and growth of the China\'s real estate market in the context of social transformation,but a wide range of government,urban residents,farmers,real estate developers and banks and other groups in the vital interests of the systemic problems is not simply reflected the problem of the housing prices rose too high or too fast,is also not limited to the local real estate market problem. This is the overall issues related to the healthy operation of the social fabric.

在社会转型大背景下发育与发展的中国房地产市场，绝非简单地表现为住房价格上涨过快或过高的问题，也并非仅限于房地产这一局部市场中存在的问题，而是广泛涉及政府、城镇居民、农民、房地产开发商和银行等群体的切身利益的系统性问题，是事关社会机体如何良性运行的全局性问题。

This indicates a systemic difference in the evaluation of the bilateral trade of these goods.

这表明一个系统性差别的双边贸易的货物。

"In general, the restructuring program will certainly take into account the interests of shareholders of shares outstanding issues, such as the injection of assets given an appropriate level of earnings ratio, more or less guarantee of the outstanding shares of the market value of the shareholders before the suspension can Maintain,"who has been in charge of a listed company's bankruptcy restructuring investment bank said," However, this will certainly need to bring out the systemic risk of loss, for example, we calculate the flow of the market value held by shareholders, will be before the suspension The market point decline from now on the basis of a calculation."

&在一般情况下，重组计划一定会考虑到股份股东的利益，如资产注入悬而未决的问题，给予的市盈率，或多或少的流通股保证适当水平股东的市场价值停牌前能够保持，&谁在上市公司破产重组投资银行负责有人说，&但是，这当然需要带出损失的系统性风险，例如，我们计算由股东占有的市场价值流，将停牌前的市场，即由现在的计算下降。&

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。