查询词典 systemic factor

Many antibodies against pro-inflammatory cytokines and inhibitors of inducible NO synthase have been produced, but most of them are agents targeting one factor and cant efficiently block the development of systemic inflammation.

尽管已经研制出许多抗促炎细胞因子抗体及诱生型NO合酶(inducible NO synthase，iNOS)抑制剂等，但多为单因素抗炎制剂，不能有效地阻断全身性炎症的发展。

BACKGROUND: It has been indicated that neuro-immuno-modulation peptide,α-melanophore-stimulating hormone, can play an effective role in anti-inflammation, antibiosis, defervescence and immunological regulation through inhibiting the release of proinflammatory factor, improving the vigor of lymphocyte and other ways, so that it has a good prospect in the prevention and treatment of systemic inflammatory response syndrome.

背景：研究表明，神经免疫调节肽α-黑素细胞刺激素(α-melanophorestimulating hormone，α-MSH)可通过抑制促炎因子释放、改善淋巴细胞活力等途径发挥其抗炎、抗菌、退热和免疫调节作用，在防治全身炎性反应综合征中可能有良好的应用前景。

The editorialists, nephrologists Drs Barry I Freedman and Thomas D DuBose Jr (Wake Forest Uniersity, Winston-Salem, NC), obsere that the two disorders share risk factors and pathophysiology and note, for example, that urinalysis proides a window into the systemic asculature, since relatiely small increases in urinary protein excretion appear to be surrogate markers for endothelial dysfunction and are an independent risk factor for systemic atherosclerosis.

肾病学专家Barry I Freedman和Thomas D DuBose Jr医生谈论道，这两种疾病享有共同的危险因子和病理生理变化，并举例说明：尿检是分析全身脉管系统的一个窗口，因为尿蛋白相对细微的升高就意味着内皮功能不全，同时也是全身动脉粥样硬化的独立危险因子。

Systemic studies environment temperature how to influence construction control, finds out linear regularity and function formula of the arch rib, selects optimal closure time, then fully meets requirements of closure precision and linear. By testing a lot of data on temperature and strain and adopting least squares collocation, this dissertation deduces the strain calculate formula that is amended by joining temperature factor, then improves accuracy of stresses testing data.

系统地研究外界温度变化对施工监控的影响，找出了拱肋变化的线性规律和函数式，选择出最佳合龙时机，保证了拱肋的合龙精度和线形要求；测试了大量温度与应力对应关系的实验数据，采用最小二乘拟合推估法，推导出温度修正后的应变计算公式，从而提高了应力测试数据的准确性。

Patients with polyarticular course JIA (19 females, three males; mean age 13.9 years; mean disease duration 6.3 years; 15 with polyarticular onset, seven with systemic onset, one with residual systemic activity; eight rheumatoid factor positive; eight with erosive disease) were treated with etanercept for up to 24 months.

22名多关节幼年型类风湿关节炎患者(19 例女性， 3例男性；平均年龄 13.9 年；平均病程 6.3 年； 15例现有多关节症状， 7例有全身症状， 1例有残余的全身症状； 8例RF阳性； 8例有骨关节侵蚀)使用etanercept治疗超过24 个月。

The project implemented a systemic investigation to the pupa period of wild silkworm comparatively, which from Shanxi, Jiangsu, Sichuan, Chongqing, Guizhou provinces and so on. According to the investigation, the pupa dormant characteristic of Shaanxi wild silkworm was found, and the individual, which pupa period was more than two months was selected. Through the hybrid genetic analysis we found that the characteristics for a long period of pupa was controlled by polygene and genetic recessively and strongly influenced by environmental conditions at the same time. To compare the performance of pupa period of the pupa dormant wild mulberry silkworm, we designed different ecological conditions. The result indicating that the temperature is the main factor in the ecological impact, but the pupa period was extended at the same temperature conditions, indicating that the additive effects of the environmental factors.

本项目实施，系统调查比较了陕西、江苏、四川、重庆、贵州等省市的野桑蚕的蛹期经过，发现了陕西野桑蚕的蛹休眠特性，筛选获得了长达2个月以上的蛹期经过个体；通过杂交遗传分析，发现长蛹期特性表现为隐性遗传，受多基因控制，同时受环境条件的强烈影响作用；通过设计不同生态条件比较蛹休眠性野桑蚕蛹期经过的表现，表明温度是主要的生态影响因子，但相同温度的野外型条件下蛹期经过延长，表明受到环境因素的综合作用。

Systemic levels of IL-6, IL-8 and TNF- a increase in patients with acute pancreatitis and correlate with the severity of the disease.A key regulator of cytokine induction is the pleiotropic transcription factor nuclear factor- K B.

核因子-κB(nuclear factor-kappa B，NF-κB)是由Rel蛋白家族成员形成的同源或异源二聚体，它几乎存在所有的细胞，不同的二聚体与不同的DNA序列结合，亲和力和转录激活能力是不一样的。

Finally, the empirical result of the single systemic factor model showed that the common factor Z had periodicity existed; that is to say, if Z was negative in average within the first quarter, then that meant the overall economic situation in that quarter was not good, and affected every enterprises credit ratings declining.

最后，单一因子模型的实证发现，共同因子存在一个周期性，即每年的第一季Z均为负，表示该季总体经济状况不好，使得平均每一家企业的信用评等均下降，每年的二四季Z均为正，表示这三季的总体经济状况良好，使得平均每一家企业的信用评等提升。

Abstract］ Objective For the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.The mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低pH常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低pH/巴氏消毒法；人纤维蛋白原、人凝血因子Ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。

Abstract］ objective for the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.methods aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with ph 4, human immunoglobulin and human hepatitis b immunoglobulin for intravenous injection with ph 4/pasteurization,treatment on human fibrinogen and human coagulation factor ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.the mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.results human albumin pasteurization inactivated vsv and sindbis virus,hrig low ph inactivated vsv and sindbis virus,hrig low ph inactivated hiv virus,ivig low ph/pasteurization inactivated hiv virus,ivig low ph inactivated hiv virus,hbig low ph/pasteurization inactivated vsv,sindbis and polio virus.conclusion suggestion about improvement on unreasonable parameter and standard of virus inactivation is made,cultivate target virus directly from final product by appropriate cell or method to monitoring viral safety of blood plasma product is advanced.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参数。方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低ph常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低ph/巴氏消毒法；人纤维蛋白原、人凝血因子ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。结果人血白蛋白巴氏灭活vsv与sindbis病毒，hrig低ph灭活vsv和sindbis病毒，hrig低ph灭活hiv病毒，ivig低ph/巴氏灭活hiv病毒，ivig低ph灭活hiv病毒，hbig低ph/巴氏灭活vsv、sindbis与polio病毒。结论建议改进病毒灭活验证标准与不合理的灭活参数；采用终产品样品通过合适细胞或方法直接培养目标病毒来有效监测血液制品的病毒安全性。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。