查询词典 synthetase

High expression of cellular asparagine synthetase is a causative factor for the resistance of leukemic cell to Lasparaginase therapy.

细胞内门冬酰胺合成酶（asparagines synthetase， AS）的表达水平与白血病细胞对左旋门冬酰胺酶耐药有关。

The bioactive screening on aldose reductase, nitric oxide synthetase, liver cancer Bel-7402, cavum oris epithelioma KB and colon cancer HCT-8 showed that paeoniflorin inhibited the nitric oxide synthetase by the rate of 83. 4% at the concentration of 5μg/ml, and paeoniflorigenone inhibited the colon cancer HCT-8 cells by the rate of 83. 2% at the concentration of 5μg/ml.

通过醛糖还原酶、NO合酶、肝癌Bel-7402、口腔上皮癌KB以及结肠癌HCT-8五种模型的生物活性筛选表明，在51μg／ml的浓度下，芍药甙对NO合酶的抑制率达83.4％，芍药甙元对结肠癌HCT-8细胞株的抑制率达83.2％，有较好的抑制作用。

Objective: To study the changes in the serum nitric oxide content and the NO synthetase activity and to provide the theoretical basis for the pathogenesis, prevention and treatment of diabetes.

提要 目的：研究实验性糖尿病大鼠血清一氧化氮(nitric oxide， NO)含量和一氧化氮合成酶(NO synthetase， NOS)活力的变化，为糖尿病发生机制的研究提供理论依据。

Gene sequence was highly homologic with a gene encoding aβ- subunit of ATP synthetase and an EST originating from a cDNA in relation to water deficit stress, which both were closely associated with the protein functioning in stress resistance and ion transportation. The results suggested that No. 1 gene sequence was involved in stress resistance of apple rootstock. No. 2 gene sequence had high homology with a gene encoding a serine/ threonine kinase protein, indicating perhaps it was a new gene encoding the serine/ threonine kinase protein in apple rootstock. The gene sequences of A1 and A2 were highly homologic with a gene encoding aβsubunit of ATP synthetase.

对得到的差异片断进行回收、测序，通过BLAST和其它植物比对，发现Ⅰ号序列与一条编码ATP合酶β亚基基因和一条水分亏缺胁迫cDNA克隆基因EST的同源性非常高，该序列编码涉及到了抗性表达、离子转运基因，可能参与了植物抗性表达，说明获得的基因序列应是与苹果砧木抗性相关的基因；Ⅱ序列与一条serine/threonine kinase蛋白激酶的蛋白序列同源性比较高，核酸比对较低，可能是具有丝氨酸/苏氨酸蛋白激酶功能的新基因。A1、A2序列与一条编码ATP合酶β亚基基因的同源性较高。

The DNA sequences around the transposon inserted site were also amplified by inverse PCR and sequenced. Multisequence alignments showed that the mutated genes were highly similar to the malonyl coenzyme A transacylaseg gene, lipopeptide synthetase B gene and sensor histidine kinase gene, respectively.

反向PCR克隆转座插入位点周边序列及测序结果表明，转座突变的基因与编码脂肽类化合物合成和调控相关的malonyl coenzyme A transacylase、lipopeptide synthetase B和sensor histidine kinase蛋白基因具有高度同源性。

Cloning of cytosolic (GS1) cDNA and chloroplast glutamine synthetase (CS2) cDNA from Pisum satium was carried out previously in our laboratory.

谷氨酰胺合成酶(Glutamine synthetase， GS， E。 C。 6。 3。 1。 2)是植物氨同化过程中的关键酶，对植物的氮素吸收和代谢起着至关重要的作用。

Cloning of cytosolic (GS1) cDNA and chloroplast glutamine synthetase (GS2) cDNA from Pisum satium was carried out previously in our laboratory.

谷氨酰胺合成酶(Glutamine synthetase，GS，E.C.6.3.1.2)是植物氨同化过程中的关键酶，对植物的氮素吸收和代谢起着至关重要的作用。

Based on the fact that aminoacyl-tRNA synthetase is a bona fide drug target for several microorganisms, including bacteria and fungi, it is plausible that it may also be effective target of Trypanosoma. In this report, the Trypanosoma brucei Leucyl-tRNA synthetase was cloned , expressed and purified to develop an in vitro enzymatic assay system.

根据亮氨酰tRNA合成酶在微生物中可作为药物靶点的事实，在新型抗锥虫药物筛选中，通过对锥虫的亮氨酰tRNA合成酶的克隆、表达和纯化，以及该酶活性测定的优化，建立了该酶抑制物的筛选系统。

No immunostaining was seen in RPE. Double staining that Kir2. 1 and glutamine synthetase, Kir2. 1 and glutamine synthetase colocalized well. Intense Kir7. 1 immunolabeling was present on the apical surface of all RPE cells and appeared to extend over the length of the apical processes. Na〓, K〓-ATPase expression varied among RPE cells, but in highly expressing cells, it co-localized with Kir7. 1. Immunoreactivity of Kir2. 1、Kir4. 1 and Kir7. 1 acomplished by ABC immunohistochemistry in monkey and human retinae got the nearly same results as bovine.

间接免疫荧光组织化学显示，Kir2.1蛋白主要分布在Müller细胞与神经元相接触的细胞膜区域；与Müller细胞的特异性标记蛋白质抗谷氨酸合成酶抗体双重标记显示其分布特性重叠，在RPE未检测Kir2.1蛋白的免疫活性存在；Kir4.1蛋白集中分布于Müller细胞的内侧突起，与GS蛋白双重标记显示其分布特性重叠，RPE未检测Kir4.1蛋白的免疫活性存在；Kir7.1主要分布于RPE游离面及其突起的全长，与特异性标记RPE突起的Ezrin蛋白完全重叠，Na〓-K〓ATP酶在不同部位的RPE表达不同，Na〓-K〓ATP高表达的RPE细胞与Kir7.1的分布特性重叠。

The ammo acid sequences deduced from the other ESTs are homologous to glutamine synthetase, lipase-like protein, decarboxylase family protein, putative AUXl-like permease, HT-ATP synthetase, Proline-rich protein, RNA transporter binding protein and cation-transporting ATPase, respectively.

摘要其它ESTs的编码产物分别与谷氛酞胺合成酶、类似脂酶、脱数酶家族蛋白、H+- ATP合成酶、激素类渗透酶、阳离子运输ATPa se、RNA运输因子结合蛋白和富含脯氮酸的蛋白等同源。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。