查询词典 synaptic

With the advantage of being highly objective and efficient,the computer-aided analysis system for synaptic numerical density based on the Disector technique,Disector Countor 1.0,would be the developmental direction for synaptic numerical density analysis.

我们开发的基于Disector技术的突触的数密度计算机辅助分析系统——Disector Countor 1.0，具备客观、高效等优点，是突触数目定量分析的发展方向。

NMDA(N-methyl-D-aspartate) receptors are a subtype of excitatory transmitters-glutamate receptor which belong to a heteromeric ligand-gated ionotropic receptors and play an important role in many complex physiological and pathological processes, such as nerve development, neuronal excitatory synaptic transmission, synaptic plasticity, central sensitization and neuronal death.

NMDA(N-methyl-D-aspartate)受体是兴奋性神经递质谷氨酸受体的一种亚型，是一种异聚体配体门控型离子通道，参与体内神经发育、神经元的兴奋性突触传递、突触可塑性、中枢敏化、神经元死亡等多种不同的生理和病理过程。

Based on above results, we conclude that the synaptic depression of thalamic input to the cortex contributes to rapid adaptation in cortical neuron, and both the thalamocortical and intracortical synaptic transmission could then enhance the degree of adaptation.

基于以上结果，我们认为，持续刺激引起的丘脑—皮层突触的抑制对皮层神经元的快速适应有贡献，而丘脑—皮层突触以及皮层—皮层突触的放大机制都可以将这一特性进一步增强。

The result indicates that the intracortical synaptic input was unchanged, but the thalamocortical synaptic input was depressed by sensory stimulation and this depression recovered with a time course that matched that of the recovery of sensory responsiveness.

结果表明，电刺激诱导出的皮层—皮层突触反应不受持续的触须刺激的影响，而电刺激诱导出的丘脑—皮层突触反应则由于持续的触须刺激而减小，而且突触反应的恢复时程与皮层细胞适应恢复的时程类似。

Two kinds changes of neuron plasticity are confirmed being related to GAP-43:(1)synaptic structural change makes GAP-43 increase ;(2) changes of synaptic transduction efficacy that long term potential and long term depression can alter GAP-43 phosphatize state and mRNA expression.

突触素(synaptophysin，P38)系一相对分子质量为38000的膜结构蛋白，存在于突触前囊泡膜，与突触的结构和功能密切相关。P38作为突触前终末特异性标记物，常用来反映突触的密度和分布。

Postsynaptic dense area and the close relationship between synaptic plasticity are essential for the maintenance of synaptic function properly.

突触后致密区与突触可塑性的关系十分密切，对于维持突触发挥正常功能至关重要。

In the presence of L-isoproterenol (through local infusion into area CA1), the theta-pulse stimulation with the parameter of 10 Hz, 150 pulses/train, 1 train, a frequency weakly modifying synaptic strength, induced a robust LTP, and this effect was blocked when DL-propranolol was co-administered. By contrast, the theta-pulse stimulation with the parameter of 5 Hz, 150 pulses/train, 3 train, a frequency strongly modifying synaptic strength, induced a significantly smaller LTP when DL-propranolol was administered into area CA1. Accordingly, DL-propranolol impaired rat's spatial learning in the water maze when infused into area CA1 20min pretraining.

正常情况下对突触传递效能仅有微小调制作用的10Hz的θ节律刺激（每串150个脉冲，1串），在CA1区局部给予L-异丙肾上腺素后，显著地诱导出LTP，这一效应可被DL-心得安所阻断；相反，正常情况下对突触传递强度有显著调制作用的5Hz的θ节律刺激（每串150个脉冲，3串），在CA1区局部给予DL-心得安后，所诱导出的LTP被显著压抑。

So investigating the effect of aluminum exposure on LTP and the biochemical indicators relative to the LTP synaptic mechanism will help to elucidate the mechanism of aluminum damaging the learning and memory on synaptic and proteinic level.

目前虽然铝对LTP损害作用的观察很多，但铝对LTP损害作用的突触机制尚未完全阐明。

They play a pivotal role in the regulation of synaptic transmission and synaptic plasticity in the central nervous system.

NMDA受体是包含谷氨酸和甘氨酸结合位点的配体门控性离子通道，在中枢神经系统的突触传递和突触可塑性调节中起着重要的作用。

To understand the basic properties, underlying mechanisms and functions of the short-term synaptic plasticity of thalamocortical visual pathway, we combined in vivo field potential recording, focal drug application technique and neuron models, to explore the short-tem synaptic plasticity of rat major thalamocortical visual pathway (from lateral geniculate nucleus to primary visual cortex) and extrageniculate pathway (from lateral posterior nucleus to primary visual cortex), as well as the role of short-term depression in the neuronal correlated firing detection.

我们结合在位场电位记录、局部加药和神经模型等方法，对不同刺激模式下大鼠丘脑皮层主要视觉通路（外侧膝状体到初级视皮层）和非主要视觉通路（膝体外通路：丘脑侧后核到初级视皮层）的短时程突触可塑性，以及短时程抑制作用对神经元同步活动检测的作用做了研究，试图了解视觉丘脑皮层突触传递短时程可塑性的基本特性、神经机制和功能。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。