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We aim to screen and identify the key potential trans-factors during hemoglobin switch. We firstly analyzed differential expression of mRNAs in erythroid induction cultures of CD34+ cells derived from normal umbilical cord blood, adult bone marrow, and bone marrow of a heterocellular hereditary persistence of fetal hemoglobin patient. We identified ZF (HCF-binding transcription factor, Zhangfei) and SH3GLB1(SH3-domain GRB2-like endophilin B1) that had differential expression in the above three cultures. Furthermore, we confirmed the different expression of the above two genes by quantitative real-time PCR.

为鉴别影响珠蛋白基因表达和开关的新的重要调节因子，我们首先分析了人脐带血、正常成人骨髓和异细胞型胎儿血红蛋白持续存在综合症患者骨髓细胞红系诱导培养物中基因表达的差异，发现ZF(HCF-binding transcription factor，Zhangfei)和SH3GLB1（SH3-domain GRB2-like endophilin B1）在这三种不同来源的红细胞内具有显著的表达差异，并通过实时定量PCR方法验证了差异的真实性。

The second phase of networking ,which occurred in the 1960s ,included three major milestones:software switching, digital transmission ,and satellite deployment,in 1965 ,american telephone and telegraph introduced the first stored program control local switch ,the 1 ees switching system ,with the ues of software control, a family of custom calling services (speed calling,call waiting ,call forwarding and three way calling ,etc ,) was mande possible, the first software program for the 1ees switching system had approximately 100,000 lines of codes, today switches may contain ten million lines of code.

第二阶段是网络化，其发生在20世纪60年代，包括三大里程碑：软件交换，数字传输，卫星的运用，在1965年，美国电话电报介绍第一个存储程序控制区域交换机，第1 ees交换系统中，软控制运用在家庭式的呼叫服务中（快速呼叫，呼叫等待，呼叫转接和三方呼叫等，成为可能，第一个软件程序，为1ees切换系统大约有 10万行代码今日交换系统可能含有1千万行的代码。

Recent work in Arabidopsis demonstrates the molecular basis of this memory of winter: vernalization causes changes in the chromatin strcture of a flowering repressor gene, FLOWERING LOCUS, that switch this gene into a repressed state that is mitotically stable.

最近对拟南芥的研究显示了植物记忆冬季的分子基础：促进成熟促使一个开花抑制基因（FLOWERING LOCUS C，FLC）的染色质结构的改变，这种改变使这个基因从抑制状态转为有丝分裂稳定。

In this thesis, we focus on the minimization of the switch activity for each 2-to-1 MUXes in the MUX tree.

在此论文里，我们针对在多工器树里面的每一个2对1多工器的交换频率做最小化的处理。

Features in this version:- Very fast - Remember all your translations - Double click a bubble to display in full screen - Great UI, the most intuitive design - Touch header to switch source and target language - Ability to delete all of the translations - Long press a bubble to delete it - Support all Languages Google Translate supports - Easy add or remove Language Pair Mobile Translator supports translating among:- English -日本語- Fran ais - Espa ol - Deutsch - Italiano -中文--Български- Cat - Hrvatski - esky - Dansk - Nederlands - Filipino - Suomi -Ελληνικ--- Indonesia - Latvieu - Lietuvi - Norsk - Polski - Português - Rom n -Русский-Српски- Slovenina - Slovenski - Svenska -Украна- Vit - Version 2.0 is submitted, Free update for existing users!

在这个版本的功能：-非常快-请记住您所有的翻译-双击泡沫中显示全屏-大用户界面，最直观的设计-触摸头切换源和目标语言-能力，以删除所有的翻译-龙记者泡沫将其删除-支持所有语言翻译支持谷歌-轻松添加或删除语言对手机之间的翻译支持翻译：-英语-日本语-法语-西班牙语-德语-意大利语-中文--Български-猫- Hrvatski -捷克-丹麦语-荷兰语-菲律宾-芬兰-Ελληνικ---印尼- Latvieu - Lietuvi -挪威语-波兰语-葡萄牙语- Rom n -Русский-Српски- Slovenina - Slovenski -瑞典-Украна-越南-提交2.0版，免费更新现有用户！

The results indicated that the interspecific competition induced the production of males and the formation of ephippia in D. magna, and high density of males might promote to switch from parthenogenic females to sexual females in D. magna.

实验结果暗示：在较高的温度下，种间竞争刺激了大型溞雄体的产生和卵鞍的形成，高密度的雄体有助于大型溞孤雌生殖雌体向两性生殖雌体的转化。

With the Tengu and Chopper VX, players can switch from ground to air in a split second to either take out enemy forces in the ground or skies.

使用天狗和机甲VX，玩家可以在几秒内从陆地切换到天空状态，干掉地面上或天空中的来犯之敌。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究，我们提出了初步的NodD操纵子激活模型：第一，四聚体是NodD蛋白的功能单位，它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子；第二，小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体，在我们的模型中，NodD四聚体缩小其V形主体的弯折角，进而缩短其DNA结合功能域的间距；第三，小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用，NodD的构象改变由蛋白质经其双铆钉位点传递给DNA；第四，只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物；第五，不排除NodD与RNA聚合酶可能有直接的相互接触位点，不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物，但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

Karatsu take high-speed, and then switch to high-speed Beijing-Tianjin-Tanggu, in Yixing Bu under the high-speed, and then take the Outer Ring Road in Tianjin, more than 10 minutes after taking Tsubo high-speed, it is up!

走唐津高速，然后转京津塘高速，在宜兴埠下高速，然后走天津外环线，十多分钟后，走津保高速，就到了！

As a new-fashioned solid state lighting source, LED has many unique advantages such as nearly no pollution of the product and in the production process; resistance to vibration; easily dimmering from 0 to 100%; operating under safe extra low voltage; continuously operating under the condition of switch-off; having a fixed direction of the light output etc. In recent years, LED's obvious improvement of luminous efficacy and photometric characteristic let it be applied for commercial purpose.

LED作为一种新颖的固体照明光源，具有生产过程以及产品几乎无污染，不怕震动，可轻易实现0~100%的连续调光，能在安全特低电压下工作，可连续工作于开关闪断的工作状态以及其光输出具有定向性等诸多独特的优势，近年来在其光效和光色上的明显进步已使它能进入商业化应用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。