查询词典 suppressor

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

My Name is Sam - 25gp Neutralize 5 terrorists in a row by performing headshots using a Sound Suppressor.

武器在装著灭音器的情况下，以爆头的方式连续击毙5个恐怖分子

The neurofibromatosis type 2 (NF2) tumor suppressor is the only gene known to be frequently involved in early development of meningiomas.

多发性神经纤维瘤2型(NF2)肿瘤抑制基因是已知唯一的经常出现在脑膜瘤早期发展过程中基因。

The carcinogenic mechanism of nitrosamine is that it may cause the changes of tumor related gene and suppressor gene in esophageal epithelisl cells.

其致癌机制研究显示，亚硝胺可引起食管上皮细胞相关癌基因抑癌基因发生改变，大大促进癌变。

Experimental results in systems with the presence and absence of sulfamic acid as a suppressor of nitrous acid are obtained.

对比了加入氨磺酸条件下的实验结果。

Two genes which were differentially expressed before and after ATRA treatment have been partly cloned, and one corresponds to a sequence known gene DPH2L with unknown function, which was first isolated from the critical region of deletion on chromosome 17p13.3 in human ovarian carcinoma, and regarded as a candidate tumor suppressor gene.

它的降调节可能参与了从细胞生长到分化／凋亡的转换过程。另一个克隆RAa7是一个未曾报道的新序列，在ATRA或4HPR反应性细胞中呈上升或下降调节，提示该基因可能也参与了细胞过程转换的调节。

The journal publishes reviews covers the whole field of the biology and biochemistry of cancer, emphasizing oncogenes and tumor suppressor genes, growth-related cell cycle control signalling, carcinogenesis mechanisms, cell transformation, immunologic control mechanisms, genetics of human cancer, control of cell proliferation, genetic and molecular control of organismic development, rational anti-tumor drug design.

该杂志主要发表有关肿瘤生物学和生物化学的综述。其内容包括：致癌基因和肿瘤抑制基因，与生长有关的细胞周期控制的信号转导，致癌机理，细胞转化，免疫控制机理，人类癌症遗传学，细胞增殖的控制，组织发育的遗传和分子控制，合理的抗肿瘤药物设计等。

Objective To develop a method for quantitative determination of biological activity of osteoclast suppressor using osteoclast as a model.

目的 以破骨细胞为模型，建立抑制破骨细胞功能药物的生物活性定量测定方法。

Ransforming growth factor beta TGF-β is a potent growth suppressor of normal epithelial cells. However, many types of invasive cancer cells (e.g. breast cancer frequently overproduce TGF-β to enhance their growth and metastasis. Quite frequently, these cells do not possess a functional type II TGF-β receptor, indicating an aberrant TGF-β signaling is responsible for promoting cell growth.

Transforming growth factor beta 对於正常的上皮细胞是一个很强的生长抑制因子，然而，许多种具有蔓延侵犯性的癌细胞常常是表现大量的 TGF-β来促进细胞生长与转移，这些癌细胞通常不表现具有功能性的第二型 TGF-β receptor，显示有另类的 TGF-β讯息传递可以促进细胞生长。

Objective To assess the role of p53 tumor suppressor gene ( wild-type p53 ) in radiosensitivity of human gastric carcinoma cell lines.

目的 评价野生型抑癌基因p53对人胃癌细胞系放射敏感性的控制作用。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。