查询词典 sulfonamide

To avoid the influence of ammonolysis, alcoholysis and hydrolysis on molecular structure identification, in this paper, derivational estimation is utilized to confirm molecular structures ofβ-naphthol-containing sulfonyl chloride intermediates. Then the structures of corresponding sulfonamide dyes are also confirmed by FTIR,~1H NMR and mass spectrometry.

为了避免磺酰氯化合物发生水解、醇解和胺解等衍生化反应影响磺酰氯化合物分子结构表征，本文采用衍生化反推法证明了β-萘酚结构磺酰氯化合物的分子结构，并利用红外光谱、核磁共振氢谱、质谱表征了含β-萘酚结构磺酰胺染料的分子结构。

This study was designed to investigate the mechanisms of histone deacetylase inhibitors(sulfonamide anilide compound referred as the "Compound") with antitumor activity against human bladder cancer cells. MATERIALS AND METHODS: Treated with different concentrations of the Compound and HCPT for different periods of time, human bladder cancer cell line BIU-87 growthwas measured by MTT assay.

材料与方法：以不同浓度的Compound和羟基喜树碱作用于体外培养的膀胱癌BIU-87细胞株；采用MTT法检测细胞生长抑制率；以流式细胞术测定不同浓度的Compound和HCPT作用前后膀胱癌细胞的调亡情况及细胞周期的变化；应用RT-PCR分析Compound和HCPT作用前后膀胱癌细胞中P21waf/cif1 mRNA表达的变化。

This study was designed to investigate the mechanisms of histone deacetylase inhibitors (sulfonamide anilide compound referred as the Compound') with antitumor activity against human bladder cancer cells. MATERIALS AND METHODS: Treated with different concentrations of the Compound and HCPT for different periods of time, human bladder cancer cell line BIU-87 growthwas measured by MTT assay.

材料与方法：以不同浓度的Compound和羟基喜树碱作用于体外培养的膀胱癌BIU-87细胞株；采用MTT法检测细胞生长抑制率；以流式细胞术测定不同浓度的Compound和HCPT作用前后膀胱癌细胞的调亡情况及细胞周期的变化；应用RT-PCR分析Compound和HCPT作用前后膀胱癌细胞中P21(上标 waf/cif1)mRNA表达的变化。

Sulfonamide anilide compound could inhibit human bladder cancer cell growth in vitro, most likely through induction of P21(superscript waf/cif1) mRNA expression and subsequent arrest of cell cycling at G1 phase.

Compound在体外能有效抑制对传统化疗耐药的人膀胱癌细胞生长，其抗肿瘤生长机制可能是通过上调P21(上标 waf/cif1)mRNA水平从而使细胞阻滞于G1期所致。

Synthesis of novel sulfonamide-prolinols and their application on the asymmetric addition of diethylzinc to benzaldehyde.

三、研究了脯氨酸衍生的新型手性磺酰胺-氨基醇的合成及其催化二乙基锌对苯甲醛的不对称加成反应 1。

Ophenyl phenol,ophenyl phenol sodium salt tetrahydrate,7ADCA,2ethyl phenyl hydrazine hydrochloride,2,3dihydrofuran,7ethyl3(2hydroxy ethyl)indole,methyl ester of etodolac; 1,8diethyl1,3,4,9tetrahydropyrano[3.4b] indole1acetic acid methyl ester,5chloro2methoxy benzoic acid,4(2aminoethyl)benzene sulfonamide,5cyano phthalide,phthalhydrazide,9thioxanthenone,n[(1,4benzodioxane2yl)carboxyl]piperazine HCL,2chloro4amino6,7dimethoxyquinazoline,2chloro benzimidazole,1(4fluorobenzyl)2chlorobenzimidazole,2methylthio4pyrimidone,5amino4imidazole carboxamide HCL,6chloro2hexanone,11oxo6.11hydrodibenzothiepin,6,11dihydrodibenzooxepin11one,10,11dihydrodibenzocyclohepten5one;dibenzosuberone,dibenzo cyclohepten5one;dibenzosuberenone,3,5dihydroxy benzoic acid,3,5dihydroxy benzyl alcohol,2mercapto benzimidazole,3,4dihydroxy benzaldehyde,3,4dihydroxy benzonitrile,2amino5chloro benzonitrile,2(4chlorophenoxy)ethyl chloride,2(4chloro phenoxy)tert,butane,ditrimethylol propane;DTMP,2,2bis(4hydroxyphenyl)butane; bisphenol B,1,1'bis(4hydroxyphenyl)cyclohexane;bisphenol Z,tetrabromobisphenolS,3,5ditertbutyl salicylic acid,3,4,5trihydroxy benzoic acid stearyl ester,1,2,4trimethoxybenzene.

华业公司产品：邻苯基苯酚，邻苯基苯酚钠盐，7氨基3去乙酰氧基头孢烷酸，邻乙基苯肼盐酸盐，2，3二氢呋喃，7乙基色氨醇，依托度酸甲酯，5氯2甲氧基苯甲酸，4(2氨乙基)苯磺酰胺，5氰基苯酞，双酮酞嗪，9噻吨酮，N〔(1，4苯并二恶烷2基)羰基〕哌嗪盐酸盐，2氯4氨基6，7一二甲氧基喹唑啉，2氯苯并咪唑，1(4氟苄基)2氯苯并咪唑，2甲硫基4嘧啶酮，5氨基咪唑4 甲酰胺盐酸盐，6氯2已酮，11氧6.11二氢苯并〔b.c〕虑平，11氧代6，11二氢二苯并氧杂卓，10，11二氢二苯并环庚烯5酮，二苯并环庚烯5酮，3，5二羟基苯甲酸，3，5二羟基苯甲醇，2巯基苯并咪唑，3，4二羟基苯甲醛，3，4二羟基苯腈，2氨基5氯苯腈，2(4氯苯氧基)1氯乙烷，2(4氯苯氧基)叔丁烷，双丙烷，2，2二(4羟基苯基)丁烷；双酚B，1，1'双(4羟基苯基)环己烷；双酚Z，2[3，5二溴4(2，3二溴丙氧基)]苯砜，3，5二叔丁基水杨酸，3，4，5三羟基苯甲酸十八烷基脂，1，2，4三甲基氧基苯。

Amino(9-deoxy)epicinchonine was synthesized from cinchonine through the Mitsunobu reaction and was treated with p-toluenesulfonyl chloride,4-chlorobenzene sulfonyl chloride respectively to give two new chiral sulfonamide s.

以辛可宁为原料，经Mitsunobu反应合成了9-氨基(9-脱氧)表辛可宁，然后分别与对甲苯磺酰氯、对氯苯磺酰氯反应，合成了两个新手性磺酰胺，其结构经红外光谱和核磁共振确证。

The result of the experiment showed that the qualitative medium - speed filter paper can be used as the material of the nitrite - detecting paper: color developing reagent A containing 4 - aminobenzene sulfonamide and N - 1 naphthyl ethylenediamine hydrochloride, and mixtures of 1 : 1 naphthylamine solution and sulfanilic acid solution as color developing reagent.

实验结果表明：定性中速滤纸可以作为亚硝酸根试纸的材料；含有4-氨基苯磺酰胺和N-1-萘基乙二胺盐酸盐的显色剂A及含有1：1的α-萘胺溶液和对氨基苯磺酸溶液的显色剂B，按1：1混合后可以作为显色剂；通过应用实验表明，亚硝酸根试纸具有体积小、便于携带、检测方便、成本低廉等特点。

In a word, sulfonamide dyes exhibit better color fastness properties on three sorts of hydrophobic fabrics, especially for sublimation fastness, in comparison with the dyes without sulfonamide group in their structures.

与结构中不含磺酰胺基的染料相比，磺酰胺染料在三种疏水性织物上具有更好的色牢度，特别是耐升华牢度明显提高。

Then two series of yellow sulfonamide dyes are synthesized by the reaction of the sulfonyl chlorides and ammonia or different fatty amines in the presence of acid-binding reagent. The structures of sulfonyl chloride intermediates and sulfonamide dyes are confirmed by FTIR,~1H NMR and mass spectrometry.

将所合成的磺酰氯化合物在缚酸剂作用下分别与含有不同碳数的饱和脂肪胺发生缩合反应，合成了两个系列黄色偶氮型磺酰胺染料，并利用红外光谱、核磁共振氢谱和质谱表征了磺酰氯中间体和磺酰胺染料的分子结构。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失