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Exogenous E2 alone has no effect on cell viability and apoptosis of H9C2 cells, but it can decrease the sensitivity of H9C2 cells to H_2O_2,hence,protect cells against apoptosis caused by oxidative stress.2Exogenous E_2 has downregulation effect on TβRⅠand TβRⅡof H9c2 cells,blocking ER may delete this effect of estradiol.H9c2 cells express ERβonly,suggests that E_2 may exert modulating effect on TGF-βpathway through ERβ.

外源性E2本身并不能影响H9c2细胞凋亡，但能够降低H9c2细胞对H_2O_2的敏感性，保护细胞抵抗氧化应激引起的凋亡。2外源性E2对H9c2细胞的TβRⅠ以及TβRⅡ具有下调作用，阻断ER可消除E2对TβRⅠ和TβRⅡ的下调作用；E2可进一步通过TGF-β通路降低受体后磷酸化smad2/3的水平；H9c2细胞仅表达ERβ，提示E2可能是通过ERβ发挥其对TGF-β通路的调控作用。

From the perspective of the colonization context and the literary history of the Japanese invaded areas of China, this paper investigates the "Hanjian 汉奸 Literature" and analyzes the differences of "Hanjian Literature" in three different colonization systems. It suggests differentiation principles in five aspects for how to delimitate "Hanjian Literature."

从殖民语境和沦陷区文学研究史角度，对"汉奸文学"加以辨析文章分析了"汉奸文学"在三种不同的殖民体制中的差别，并在如何界定"汉奸文学"的问题上，提出五个方面的区分原则。

The obtained electronic configuration suggests electron delocalization in the compounds.

计算得的化合物的电子结构说明在Cu-Mo-S簇合物中存在电子的离域现象。

If his demeanour suggests his heart does not permanently skip to the joys of spring, it's because that's the way he is.

如果他的行动表明他的心永远不会放弃对快乐的追求，就说明那的确是他的方式。

As such, it rejects not only radiometric and isochron dating of the age of the Earth, arguing that they are based on debatable assumptions, but also approaches such as ice core dating and dendrochronology, which make the barest of assumptions of uniformitarianism, and which hint that the Earth is far older than the Ussher-Lightfoot Calendar suggests.

如同这个，不仅拒绝放射性和等时线地球年代测定方法，争论基于可争论的假定，而且采用这类冰核和树木年代学测定，树木年代学使得均变论假定一览无遗和暗示了地球比Ussher-Lightfoot日历更为古老。

It is hard to gauge whether Mr Bush is as annoyed with Ms Pelosi, or as supportive of Mr Richardson as the official word suggests - after all, guile and deniability are useful political tools, too.

很难评测布什先生是否讨厌Pelosi夫人或者如官方宣称的那样支持Richardson先生。毕竟，政客们狡辩和否认的本事能让他们如鱼得水。

To get a successful grip on organizing documents, bills, and other materials, Denton suggests the following tips.

如何成功地组织文件、账单和其他材料， Denton 提供了如下建议。

This suggests that age is not the main parameter governing Li depletion in our targets.

这表明在我们的样本中，年龄不会成为锂衰减的主要影响因素。

Therefore, this research suggests that teachers should understand pupils' learning styles,train them to be the ones with mathematics proficiencies, build a team of cooperative learning , and depolarize their learning styles to reinforce pupils' performance and happiness in learning mathematics.

因此，本研究建议教学者应培养具有数学熟练性的国小学童、了解学生学习风格、建构一个合作学习的团体及使学童学习风格去极化，期待可以使学生学数学学得更好、更快乐。

These data consistent with results of pharmacological experiments and further suggests that depolymerization of actin filaments is prerequisite to initiate stomatal movement.

结合我们的药理学实验结果，进一步说明微丝解聚是启动气孔运动的前提条件。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。